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This paper explores the reconstruction of a space-dependent parameter in inverse diffusion problems, proposing a shape-optimization-based approach. We consider a Robin boundary condition, physically motivated in diffuse optical tomography…

Numerical Analysis · Mathematics 2026-01-27 Manabu Machida , Hirofumi Notsu , Julius Fergy Tiongson Rabago

Diffusion MRI is a neuroimaging technique measuring the anatomical structure of tissues. Using diffusion MRI to construct the connections of tissues, known as fiber tracking, is one of the most important uses of diffusion MRI. Many…

Methodology · Statistics 2019-06-18 Zhou Lan , Brian J Reich

Although EDM aims to unify the design space of diffusion models, its reliance on fixed Gaussian noise prevents it from explaining emerging flow-based methods that diffuse arbitrary noise. Moreover, our study reveals that EDM's forcible…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Xingyu Qiu , Mengying Yang , Xinghua Ma , Dong Liang , Fanding Li , Gongning Luo , Wei Wang , Kuanquan Wang , Shuo Li

The oscillations observed in many time series, particularly in biomedicine, exhibit morphological variations over time. These morphological variations are caused by intrinsic or extrinsic changes to the state of the generating system,…

Applications · Statistics 2021-03-30 Yu-Ting Lin , John Malik , Hau-Tieng Wu

Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…

Medical Physics · Physics 2024-01-09 Nathan Dermul , Hans Dierckx

Electrocardiogram (ECG) signals are beneficial in diagnosing cardiovascular diseases, which are one of the leading causes of death. However, they are often contaminated by noise artifacts and affect the automatic and manual diagnosis…

Signal Processing · Electrical Eng. & Systems 2022-08-19 Radhika Dua , Jiyoung Lee , Joon-myoung Kwon , Edward Choi

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

Optimization and Control · Mathematics 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

Diffusion probabilistic models have achieved mainstream success in many generative modeling tasks, from image generation to inverse problem solving. A distinct feature of these models is that they correspond to deep hierarchical latent…

Machine Learning · Computer Science 2024-12-30 Yibo Yang , Justus C. Will , Stephan Mandt

Equation-free modeling aims at extracting low-dimensional macroscopic dynamics from complex high-dimensional systems that govern the evolution of microscopic states. This algorithm relies on lifting and restriction operators that map…

Dynamical Systems · Mathematics 2022-01-03 Tracy Chin , Jacob Ruth , Clayton Sanford , Rebecca Santorella , Paul Carter , Bjorn Sandstede

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Computational Engineering, Finance, and Science · Computer Science 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

Inverse problems are prevalent across various disciplines in science and engineering. In the field of computer vision, tasks such as inpainting, deblurring, and super-resolution are commonly formulated as inverse problems. Recently,…

Machine Learning · Computer Science 2025-01-07 Shayan Mohajer Hamidi , En-Hui Yang

Diffusion models generate data by learning to reverse a forward process, where samples are progressively perturbed with Gaussian noise according to a predefined noise schedule. From a geometric perspective, each noise schedule corresponds…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Teng Zhang , Hongxu Jiang , Kuang Gong , Wei Shao

Electroencephalogram (EEG) classification has been widely used in various medical and engineering applications, where it is important for understanding brain function, diagnosing diseases, and assessing mental health conditions. However,…

Signal Processing · Electrical Eng. & Systems 2024-08-20 Mingzhi Chen , Yiyu Gui , Yuqi Su , Yuesheng Zhu , Guibo Luo , Yuchao Yang

In this paper, we apply a recently developed nonparametric modeling approach, the "diffusion forecast", to predict the time-evolution of Fourier modes of turbulent dynamical systems. While the diffusion forecasting method assumes the…

Chaotic Dynamics · Physics 2016-03-23 Tyrus Berry , John Harlim

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

Heart disease remains a significant threat to human health. As a non-invasive diagnostic tool, the electrocardiogram (ECG) is one of the most widely used methods for cardiac screening. However, the scarcity of high-quality ECG data, driven…

Machine Learning · Computer Science 2025-07-22 Yongfan Lai , Jiabo Chen , Deyun Zhang , Yue Wang , Shijia Geng , Hongyan Li , Shenda Hong

While energy-based models (EBMs) exhibit a number of desirable properties, training and sampling on high-dimensional datasets remains challenging. Inspired by recent progress on diffusion probabilistic models, we present a diffusion…

Machine Learning · Computer Science 2021-03-30 Ruiqi Gao , Yang Song , Ben Poole , Ying Nian Wu , Diederik P. Kingma

We study the seismic inverse problem for the recovery of subsurface properties in acoustic media. In order to reduce the ill-posedness of the problem, the heterogeneous wave speed parameter to be recovered is represented using a limited…

Analysis of PDEs · Mathematics 2020-09-10 Florian Faucher , Otmar Scherzer , Hélène Barucq

Score-based diffusion models are a recently developed framework for posterior sampling in Bayesian inverse problems with a state-of-the-art performance for severely ill-posed problems by leveraging a powerful prior distribution learned from…

We consider a time-dependent linear diffusion equation together with a related inverse boundary value problem. The aim of the inverse problem is to determine, based on observations on the boundary, the non-homogeneous diffusion coefficient…

Numerical Analysis · Mathematics 2016-09-21 Lauri Mustonen