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Detecting specific target analytes and differentiating them from interfering background effects is a crucial but challenging task in complex multi-component solutions commonly encountered in environmental, chemical, biological, and medical…
A broadband detection method with coherent laser pulses exciting surface plasmons is investigated. The intensity and phase characteristics of the reflected light in Kretschmann configuration are calculated. It is shown that by mixing…
We show the theoretical and experimental combination of acoustic and optical methods for the in situ quantitative evaluation of the density, the viscosity and the thickness of soft layers adsorbed on chemically tailored metal surfaces. For…
We present results from an instrument combining surface acoustic wave (SAW) propagation and surface plasmon resonance (SPR) measurements. The objective is to use two independent methods, the former based on adsorbed mass change measurements…
Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g.,…
Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that…
In this study, we present a highly sensitive Surface Plasmon Resonance (SPR)-based biosensor integrated with a circular-lattice Photonic Crystal Fiber (PCF) for early-stage cancer detection. The proposed sensor leverages the synergy between…
The measurement of in-plane birefringence ($\Delta{n}$) of ultrathin film is challenging due to a significant deviation of physical properties of materials in ultrathin regime as compared to that in bulk state. Surface plasmon resonance…
This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…
A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with…
Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…
We present a multiscale quantum mechanics/classical (QM/MM) approach for modeling surface-enhanced infrared absorption (SEIRA) spectra of molecules adsorbed on plasmonic nanostructures. The molecular subsystem is described at the density…
We present a simulation guided design for a multilayer surface plasmon resonance (SPR) based biosensor capable of detecting refractive index changes in a target induced by analytes. Surface plasmons are excited using a hybrid Kretschmann…
Sensors based on the phenomenon of surface plasmon resonance have limited sensitivity, up to 123 degree/Refractive Index Unit, which restricts their applicability in detecting subtle changes gin biological media (around 10-5 RIU). To…
The spatial impulse response (SIR) method is a well-known approach to calculate transient acoustic fields of arbitrary-shape transducers. It involves the evaluation of a time-dependent surface integral. Although analytic expressions of the…
We present a numerical study of a divergent-beam Kretschmann surface plasmon resonance (SPR) platform for multiplexed malaria biosensing. A Powell-lens-generated angular fan enables camera-based angular interrogation of spatially separated…
Photonic crystal fiber (PCF)-based plasmonic sensors have gained considerable attention because of their highly sensitive performance and broad range of sensing regimes. In this work, a relatively simple ultra-sensitive PCF-based surface…
Surface Enhanced Infrared Absorption (SEIRA) is an experimental method where trace amount of a compound can be detected with high sensibility. This high detection sensibility is the result of the interaction of the molecules with a…
In this work, we proposed a high resolution D-shaped photonic crystal fiber (PCF) surface plasmon resonance (SPR) sensor based on gold grating. Gold grating is introduced to modulate the resonance wavelength and enhance the refractive index…
By means of the in situ electrokinetic assessment of aqueous particles in conjunction with the addition of anionic adsorbates, we develop and examine a new approach to the scalable characterization of the specific accessible surface area of…