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Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Image reconstruction of low-count positron emission tomography (PET) data is challenging. Kernel methods address the challenge by incorporating image prior information in the forward model of iterative PET image reconstruction. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Siqi Li , Kuang Gong , Ramsey D. Badawi , Edward J. Kim , Jinyi Qi , Guobao Wang

Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 William Whiteley , Vladimir Panin , Chuanyu Zhou , Jorge Cabello , Deepak Bharkhada , Jens Gregor

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Kernelized maximum-likelihood (ML) expectation maximization (EM) methods have recently gained prominence in PET image reconstruction, outperforming many previous state-of-the-art methods. But they are not immune to the problems of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Shiyao Guo , Yuxia Sheng , Shenpeng Li , Li Chai , Jingxin Zhang

This paper presents a robust multi-domain network designed to restore low-quality amyloid PET images acquired in a short period of time. The proposed method is trained on pairs of PET images from short (2 minutes) and standard (20 minutes)…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Hyoung Suk Park , Young Jin Jeong , Kiwan Jeon

In PET, the amount of relative (signal-dependent) noise present in different body regions can be significantly different and is inherently related to the number of counts present in that region. The number of counts in a region depends, in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ye Li , Jianan Cui , Junyu Chen , Guodong Zeng , Scott Wollenweber , Floris Jansen , Se-In Jang , Kyungsang Kim , Kuang Gong , Quanzheng Li

Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Rui Hu , Jianan Cui , Chengjin Yu , Yunmei Chen , Huafeng Liu

Quantitative accuracy and thus diagnostic precision in Emission Tomography is impaired by the inherent random characteristics of the data acquisition leading to statistical image noise. Edge preserving spatial variation regularized…

Medical Physics · Physics 2019-10-02 Andre Salomon , Andriy Andreyev , Andreas Goedicke

The kernel reconstruction is a method that reduces noise in dynamic positron emission tomography (PET) by exploiting spatial correlations in the PET image. Although this method works well for large anatomical regions with relatively slow…

Medical Physics · Physics 2025-07-31 Alan Miranda , Steven Staelens

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Bo Zhou , Yu-Jung Tsai , Jiazhen Zhang , Xueqi Guo , Huidong Xie , Xiongchao Chen , Tianshun Miao , Yihuan Lu , James S. Duncan , Chi Liu

Sparse-view computed tomography (CT) has been adopted as an important technique for speeding up data acquisition and decreasing radiation dose. However, due to the lack of sufficient projection data, the reconstructed CT images often…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Hong Wang , Minghao Zhou , Dong Wei , Yuexiang Li , Yefeng Zheng

Dynamic PET kinetic modeling increasingly demands voxelwise uncertainty quantification and robust model selection. Yet total-body PET (TB-PET) data volumes make conventional Bayesian approaches, such as per-voxel MCMC, computationally…

Applications · Statistics 2026-03-17 Qinlin Gu , Gaelle M. Emvalomenos , Evan D. Morris , Clara Grazian , Steven R. Meikle

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

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