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Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Machine learning (ML) has rapidly advanced in recent years, revolutionizing fields such as finance, medicine, and cybersecurity. In malware detection, ML-based approaches have demonstrated high accuracy; however, their lack of transparency…

Cryptography and Security · Computer Science 2025-04-09 Harikha Manthena , Shaghayegh Shajarian , Jeffrey Kimmell , Mahmoud Abdelsalam , Sajad Khorsandroo , Maanak Gupta

Artificial intelligence holds great promise in medical imaging, especially histopathological imaging. However, artificial intelligence algorithms cannot fully explain the thought processes during decision-making. This situation has brought…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Tuncay Yiğit , Nilgün Şengöz , Özlem Özmen , Jude Hemanth , Ali Hakan Işık

The extensive utilization of biometric authentication systems have emanated attackers / imposters to forge user identity based on morphed images. In this attack, a synthetic image is produced and merged with genuine. Next, the resultant…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Rudresh Dwivedi , Ritesh Kumar , Deepak Chopra , Pranay Kothari , Manjot Singh

Artificial Intelligence techniques can be used to classify a patient's physical activities and predict vital signs for remote patient monitoring. Regression analysis based on non-linear models like deep learning models has limited…

Artificial Intelligence · Computer Science 2024-10-28 Thanveer Shaik , Xiaohui Tao , Haoran Xie , Lin Li , Juan D. Velasquez , Niall Higgins

Analysis of microscopy images is one important tool in many fields of biomedical research, as it allows the quantification of a multitude of parameters at the cellular level. However, manual counting of these images is both tiring and…

Computer Vision and Pattern Recognition · Computer Science 2013-11-13 P. A Nogueira

Artificial intelligence has become pervasive across disciplines and fields, and biomedical image and signal processing is no exception. The growing and widespread interest on the topic has triggered a vast research activity that is…

Machine Learning · Computer Science 2022-07-12 Guang Yang , Arvind Rao , Christine Fernandez-Maloigne , Vince Calhoun , Gloria Menegaz

LangXAI is a framework that integrates Explainable Artificial Intelligence (XAI) with advanced vision models to generate textual explanations for visual recognition tasks. Despite XAI advancements, an understanding gap persists for…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Truong Thanh Hung Nguyen , Tobias Clement , Phuc Truong Loc Nguyen , Nils Kemmerzell , Van Binh Truong , Vo Thanh Khang Nguyen , Mohamed Abdelaal , Hung Cao

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Interpretability in object detection provides crucial confidence support for clinical auxiliary diagnosis. However, in tiny bacteria detection, traditional explanation methods often suffer from blurred foreground boundaries and diffuse…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Wanying Tan , Shuo Yan , Dazhi Huang , Yazheng Liu , Zili Shao , Rufeng Chen , Hechang Chen , Mude Shi , Tianxing Ji , Sihong Xie

Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation…

Machine Learning · Computer Science 2022-12-09 Weina Jin , Xiaoxiao Li , Mostafa Fatehi , Ghassan Hamarneh

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Recently, artificial intelligence and machine learning in general have demonstrated remarkable performances in many tasks, from image processing to natural language processing, especially with the advent of deep learning. Along with…

Machine Learning · Computer Science 2020-10-23 Erico Tjoa , Cuntai Guan

Deep learning is becoming increasingly adopted in business and industry due to its ability to transform large quantities of data into high-performing models. These models, however, are generally regarded as black boxes, which, in spite of…

Machine Learning · Computer Science 2023-02-21 Stefan Druc , Peter Wooldridge , Adarsh Krishnamurthy , Soumik Sarkar , Aditya Balu
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