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Fine-tuning large language models (LLMs) to align with human preferences has driven the success of systems such as Gemini and ChatGPT. However, approaches like Reinforcement Learning from Human Feedback (RLHF) remain computationally…

Machine Learning · Computer Science 2026-05-25 Miria Feng , Mert Pilanci

Enhancing the conformity of large language models (LLMs) to human preferences remains an ongoing research challenge. Recently, offline approaches such as Direct Preference Optimization (DPO) have gained prominence as attractive options due…

Machine Learning · Computer Science 2024-09-05 Kaihui Chen , Hao Yi , Qingyang Li , Tianyu Qi , Yulan Hu , Fuzheng Zhang , Yong Liu

Diffusion models have achieved promising results for Structure-Based Drug Design (SBDD). Nevertheless, high-quality protein subpocket and ligand data are relatively scarce, which hinders the models' generation capabilities. Recently, Direct…

Biomolecules · Quantitative Biology 2026-02-11 Xiwei Cheng , Xiangxin Zhou , Yuwei Yang , Yu Bao , Quanquan Gu

As language models continue to scale, Large Language Models (LLMs) have exhibited emerging capabilities in In-Context Learning (ICL), enabling them to solve language tasks by prefixing a few in-context demonstrations (ICDs) as context.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hongrui Jia , Chaoya Jiang , Haiyang Xu , Wei Ye , Mengfan Dong , Ming Yan , Ji Zhang , Fei Huang , Shikun Zhang

Recent advancements in human preference optimization, originally developed for Large Language Models (LLMs), have shown significant potential in improving text-to-image diffusion models. These methods aim to learn the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Amir Saeidi , Yiran Luo , Agneet Chatterjee , Shamanthak Hegde , Bimsara Pathiraja , Yezhou Yang , Chitta Baral

Reinforcement Learning from Human Feedback (RLHF) is currently the most widely used method to align large language models (LLMs) with human preferences. Existing RLHF methods can be roughly categorized as either reward-based or reward-free.…

Computation and Language · Computer Science 2024-10-11 Shusheng Xu , Wei Fu , Jiaxuan Gao , Wenjie Ye , Weilin Liu , Zhiyu Mei , Guangju Wang , Chao Yu , Yi Wu

Reinforcement Learning from Human Feedback (RLHF) has emerged as a pivotal tool for aligning large language models (LLMs) with human preferences. Direct Preference Optimization (DPO), one of the most popular approaches, formulates RLHF as a…

Machine Learning · Computer Science 2024-10-10 Jiafan He , Huizhuo Yuan , Quanquan Gu

Preference alignment in Large Language Models (LLMs) has significantly improved their ability to adhere to human instructions and intentions. However, existing direct alignment algorithms primarily focus on relative preferences and often…

Machine Learning · Computer Science 2025-05-13 Shenao Zhang , Zhihan Liu , Boyi Liu , Yufeng Zhang , Yingxiang Yang , Yongfei Liu , Liyu Chen , Tao Sun , Zhaoran Wang

The success of Direct Preference Optimization (DPO) in mitigating hallucinations in Vision Language Models (VLMs) critically hinges on the true reward gaps within preference pairs. However, current methods, typically relying on ranking or…

Computation and Language · Computer Science 2025-11-25 Lehan He , Zeren Chen , Zhelun Shi , Tianyu Yu , Jing Shao , Lu Sheng

Direct Preference Optimization (DPO) is successful for alignment in LLMs but still faces challenges in text-to-image generation. Existing studies are confined to denoising diffusion models while overlooking flow-matching, and suffer from an…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Kesong Li , Yixuan Xu , Kuo-kun Tseng , Weiyi Lu , Kan Liu , Tao Lan

Human image generation is a key focus in image synthesis due to its broad applications, but even slight inaccuracies in anatomy, pose, or details can compromise realism. To address these challenges, we explore Direct Preference Optimization…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sanghyeon Na , Yonggyu Kim , Hyunjoon Lee

Direct Preference Optimization (DPO) has been proposed as an effective and efficient alternative to reinforcement learning from human feedback (RLHF). However, neither RLHF nor DPO take into account the fact that learning certain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Florinel-Alin Croitoru , Vlad Hondru , Radu Tudor Ionescu , Nicu Sebe , Mubarak Shah

Direct Preference Optimization (DPO) has become a popular approach for aligning language models using pairwise preferences. However, in practical post-training pipelines, on-policy generation typically yields multiple candidate responses…

Machine Learning · Computer Science 2025-06-23 Taneesh Gupta , Rahul Madhavan , Xuchao Zhang , Nagarajan Natarajan , Chetan Bansal , Saravan Rajmohan

Without using explicit reward, direct preference optimization (DPO) employs paired human preference data to fine-tune generative models, a method that has garnered considerable attention in large language models (LLMs). However, exploration…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yunhong Lu , Qichao Wang , Hengyuan Cao , Xierui Wang , Xiaoyin Xu , Min Zhang

Direct preference optimization (DPO), a widely adopted offline preference optimization algorithm, aims to align large language models (LLMs) with human-desired behaviors using pairwise preference data. However, the generation of the winning…

Computation and Language · Computer Science 2025-02-19 Yuxin Jiang , Bo Huang , Yufei Wang , Xingshan Zeng , Liangyou Li , Yasheng Wang , Xin Jiang , Lifeng Shang , Ruiming Tang , Wei Wang

Diffusion models have achieved remarkable progress in text-to-image generation, yet aligning them with human preference remains challenging due to the presence of multiple, sometimes conflicting, evaluation metrics (e.g., semantic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Dipesh Tamboli , Souradip Chakraborty , Aditya Malusare , Biplab Banerjee , Amrit Singh Bedi , Vaneet Aggarwal

Existing open-source multimodal large language models (MLLMs) generally follow a training process involving pre-training and supervised fine-tuning. However, these models suffer from distribution shifts, which limit their multimodal…

Computation and Language · Computer Science 2025-04-08 Weiyun Wang , Zhe Chen , Wenhai Wang , Yue Cao , Yangzhou Liu , Zhangwei Gao , Jinguo Zhu , Xizhou Zhu , Lewei Lu , Yu Qiao , Jifeng Dai

Direct Preference Optimization (DPO) has recently been applied as a post-training technique for text-to-video diffusion models. To obtain training data, annotators are asked to provide preferences between two videos generated from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Ziyi Wu , Anil Kag , Ivan Skorokhodov , Willi Menapace , Ashkan Mirzaei , Igor Gilitschenski , Sergey Tulyakov , Aliaksandr Siarohin

Fairness in Continual Learning for Large Multimodal Models (LMMs) is an emerging yet underexplored challenge, particularly in the presence of imbalanced data distributions that can lead to biased model updates and suboptimal performance…

Machine Learning · Computer Science 2026-03-31 Thanh-Dat Truong , Huu-Thien Tran , Jackson Cothren , Bhiksha Raj , Khoa Luu

Direct preference optimization (DPO) is a form of reinforcement learning from human feedback (RLHF) where the policy is learned directly from preferential feedback. Although many models of human preferences exist, the critical task of…

Machine Learning · Computer Science 2025-03-04 Branislav Kveton , Xintong Li , Julian McAuley , Ryan Rossi , Jingbo Shang , Junda Wu , Tong Yu
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