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Large Language Models (LLMs) hold significant promise for improving clinical decision support and reducing physician burnout by synthesizing complex, longitudinal cancer Electronic Health Records (EHRs). However, their implementation in…

Computation and Language · Computer Science 2026-01-12 Dongchen Li , Jitao Liang , Wei Li , Xiaoyu Wang , Longbing Cao , Kun Yu

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

The integration of multimodal Electronic Health Records (EHR) data has significantly advanced clinical predictive capabilities. Existing models, which utilize clinical notes and multivariate time-series EHR data, often fall short of…

Computation and Language · Computer Science 2025-02-27 Yinghao Zhu , Changyu Ren , Zixiang Wang , Xiaochen Zheng , Shiyun Xie , Junlan Feng , Xi Zhu , Zhoujun Li , Liantao Ma , Chengwei Pan

Multi-modal language model has made advanced progress in vision and audio, but still faces significant challenges in dealing with complex reasoning tasks in the time series domain. The reasons are twofold. First, labels for multi-modal time…

Machine Learning · Computer Science 2025-03-10 Haochuan Zhang , Chunhua Yang , Jie Han , Liyang Qin , Xiaoli Wang

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

This paper develops the first question answering dataset (DrugEHRQA) containing question-answer pairs from both structured tables and unstructured notes from a publicly available Electronic Health Record (EHR). EHRs contain patient records,…

Artificial Intelligence · Computer Science 2022-05-04 Jayetri Bardhan , Anthony Colas , Kirk Roberts , Daisy Zhe Wang

Selecting an appropriate reasoning method for a given query remains a key challenge in language model generation. Existing approaches typically generate multiple candidate responses and use an aggregation strategy to select the output…

Machine Learning · Computer Science 2025-11-11 Bao Nguyen , Hieu Trung Nguyen , Ruifeng She , Xiaojin Fu , Viet Anh Nguyen

We propose a novel framework for electrolaryngeal speech intelligibility enhancement through the use of robust linguistic encoders. Pretraining and fine-tuning approaches have proven to work well in this task, but in most cases, various…

Emotion recognition is a crucial task for human conversation understanding. It becomes more challenging with the notion of multimodal data, e.g., language, voice, and facial expressions. As a typical solution, the global- and the local…

Computation and Language · Computer Science 2024-01-31 Cam-Van Thi Nguyen , Anh-Tuan Mai , The-Son Le , Hai-Dang Kieu , Duc-Trong Le

In response to the pressing need for advanced clinical problem-solving tools in healthcare, we introduce BooksMed, a novel framework based on a Large Language Model (LLM). BooksMed uniquely emulates human cognitive processes to deliver…

Foundation models trained on patient electronic health records (EHRs) require tokenizing medical data into sequences of discrete vocabulary items. Existing tokenizers treat medical codes from EHRs as isolated textual tokens. However, each…

Computation and Language · Computer Science 2025-07-01 Xiaorui Su , Shvat Messica , Yepeng Huang , Ruth Johnson , Lukas Fesser , Shanghua Gao , Faryad Sahneh , Marinka Zitnik

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

Computation and Language · Computer Science 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

Combinatorial medication recommendation(CMR) is a fundamental task of healthcare, which offers opportunities for clinical physicians to provide more precise prescriptions for patients with intricate health conditions, particularly in the…

Artificial Intelligence · Computer Science 2025-01-14 Jie Tan , Yu Rong , Kangfei Zhao , Tian Bian , Tingyang Xu , Junzhou Huang , Hong Cheng , Helen Meng

Multi-modal multi-hop question answering involves answering a question by reasoning over multiple input sources from different modalities. Existing methods often retrieve evidences separately and then use a language model to generate an…

Computation and Language · Computer Science 2023-08-08 Qian Yang , Qian Chen , Wen Wang , Baotian Hu , Min Zhang

In modern electronic medical records (EMR) much of the clinically important data - signs and symptoms, symptom severity, disease status, etc. - are not provided in structured data fields, but rather are encoded in clinician generated…

Computation and Language · Computer Science 2014-08-10 Son Doan , Mike Conway , Tu Minh Phuong , Lucila Ohno-Machado

Electronic health records (EHRs) are rich clinical data sources but complex repositories of patient data, spanning structured elements (demographics, vitals, lab results, codes), unstructured clinical notes and other modalities of data.…

Artificial Intelligence · Computer Science 2025-08-25 Sonish Sivarajkumar , Hang Zhang , Yuelyu Ji , Maneesh Bilalpur , Xizhi Wu , Chenyu Li , Min Gu Kwak , Shyam Visweswaran , Yanshan Wang