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Related papers: Motif Diversity in Human Liver ChIP-seq Data Using…

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Many time series, particularly health data streams, can be best understood as a sequence of phenomenon or events, which we call \textit{motifs}. A time series motif is a short trace segment which may implicitly capture an underlying…

Machine Learning · Computer Science 2025-05-26 Josephine Lamp , Mark Derdzinski , Christopher Hannemann , Sam Hatfield , Joost van der Linden

Frequent and structurally related subgraphs, also known as network motifs, are valuable features of many graph datasets. However, the high computational complexity of identifying motif sets in arbitrary datasets (motif mining) has limited…

Machine Learning · Computer Science 2022-06-08 Carlos Oliver , Dexiong Chen , Vincent Mallet , Pericles Philippopoulos , Karsten Borgwardt

Heterogeneous Information Networks (HIN) has been widely used in recommender systems (RSs). In previous HIN-based RSs, meta-path is used to compute the similarity between users and items. However, existing meta-path based methods only…

Social and Information Networks · Computer Science 2019-08-27 Huan Zhao , Yingqi Zhou , Yangqiu Song , Dik Lun Lee

Detecting repeating patterns of different lengths in time series, also called variable-length motifs, has received a great amount of attention by researchers and practitioners. Despite the significant progress that has been made in recent…

Machine Learning · Computer Science 2019-11-22 Yifeng Gao , Jessica Lin

The discovery of motifs underlying gene expression is a challenging one. Some of these motifs are known transcription factors, but sequence inspection often provides valuable clues, even discovery of novel motifs with uncharacterized…

Genomics · Quantitative Biology 2007-05-23 Arvind Rao , Alfred O. Hero , David J. States , James Douglas Engel

In mixed-initiative co-creation tasks, wherein a human and a machine jointly create items, it is important to provide multiple relevant suggestions to the designer. Quality-diversity algorithms are commonly used for this purpose, as they…

Neural and Evolutionary Computing · Computer Science 2023-04-18 Roberto Gallotta , Kai Arulkumaran , L. B. Soros

Creatures in the real world constantly encounter new and diverse challenges they have never seen before. They will often need to adapt to some of these tasks and solve them in order to survive. This almost endless world of novel challenges…

Neural and Evolutionary Computing · Computer Science 2023-05-03 Emma Stensby Norstein , Kai Olav Ellefsen , Kyrre Glette

Motif extraction is an important task in motif based molecular representation learning. Previously, machine learning approaches employing either rule-based or string-based techniques to extract motifs. Rule-based approaches may extract…

Quantitative Methods · Quantitative Biology 2023-12-27 Zhaoning Yu , Hongyang Gao

In complex systems, groups of interacting objects may form prevalent and persistent spatiotemporal patterns, which we refer to as motifs. These motifs can exhibit features that reveal how individual objects interact with one another.…

Biological Physics · Physics 2025-12-12 Ying Chen Lim , Rakesh Das , Tetsuya Hiraiwa , N. Duane Loh

Brain-body co-optimization suffers from fragile co-adaptation where brains become over-specialized for particular bodies, hindering their ability to transfer well to others. Evolutionary algorithms tend to discard such low-performing…

Robotics · Computer Science 2025-04-10 Alican Mertan , Nick Cheney

In the last fifteen years, data series motif and discord discovery have emerged as two useful and well-used primitives for data series mining, with applications to many domains, including robotics, entomology, seismology, medicine, and…

Databases · Computer Science 2020-09-01 Michele Linardi , Yan Zhu , Themis Palpanas , Eamonn Keogh

Background: DNA, RNA, and protein sequence motifs can be recognition sites for biological functions such as regulation, DNA base modification, and molecular binding in general. The gain and loss of such motifs can carry important…

Genomics · Quantitative Biology 2022-10-19 Afif Elghraoui , Faramarz Valafar

Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…

Machine Learning · Computer Science 2024-12-31 Anand Karna , Naina Khan , Rahul Rauniyar , Prashant Giridhar Shambharkar

Biological sequences may contain patterns that are signal important biomolecular functions; a classical example is regulation of gene expression by transcription factors that bind to specific patterns in genomic promoter regions. In motif…

Applications · Statistics 2015-06-04 Luis E. Carvalho

Ensuring that generative AI systems align with human values is essential but challenging, especially when considering multiple human values and their potential trade-offs. Since human values can be personalized and dynamically change over…

Artificial Intelligence · Computer Science 2024-10-28 Xinran Wang , Qi Le , Ammar Ahmed , Enmao Diao , Yi Zhou , Nathalie Baracaldo , Jie Ding , Ali Anwar

Network motif provides a way to uncover the basic building blocks of most complex networks. This task usually demands high computer processing, specially for motif with 5 or more vertices. This paper presents an extended methodology with…

Data Structures and Algorithms · Computer Science 2018-04-27 Luis A. A. Meira , Vinícius R. Máximo , Alvaro L. Fazenda , Arlindo F. da Conceição

Mixed Integer Linear Programming (MILP) is essential for modeling complex decision-making problems but faces challenges in computational tractability and requires expert formulation. Current deep learning approaches for MILP focus on…

Machine Learning · Computer Science 2025-02-24 Sirui Li , Janardhan Kulkarni , Ishai Menache , Cathy Wu , Beibin Li

Quality-Diversity has emerged as a powerful family of evolutionary algorithms that generate diverse populations of high-performing solutions by implementing local competition principles inspired by biological evolution. While these…

Neural and Evolutionary Computing · Computer Science 2025-02-05 Maxence Faldor , Robert Tjarko Lange , Antoine Cully

Topological features of gene regulatory networks can be successfully reproduced by a model population evolving under selection for short dynamical attractors. The evolved population of networks exhibit motif statistics, summarized by…

Molecular Networks · Quantitative Biology 2016-08-11 Burçin Danacı , Mehmet Ali Anıl , Ayşe Erzan

The LIPGENE-SU.VI.MAX study, like many others, recorded high dimensional continuous phenotypic data and categorical genotypic data. LIPGENE-SU.VI.MAX focuses on the need to account for both phenotypic and genetic factors when studying the…