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Live-cell imaging (LCI) technology enables the detailed spatio-temporal characterization of living cells at the single-cell level, which is critical for advancing research in the life sciences, from biomedical applications to bioprocessing.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Johannes Seiffarth , Keitaro Kasahara , Michelle Bund , Benita Lückel , Richard D. Paul , Matthias Pesch , Lennart Witting , Michael Bott , Dietrich Kohlheyer , Katharina Nöh

Recent research in the field of computer vision strongly focuses on deep learning architectures to tackle image processing problems. Deep neural networks are often considered in complex image processing scenarios since traditional computer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Marcel P. Schilling , Luca Rettenberger , Friedrich Münke , Haijun Cui , Anna A. Popova , Pavel A. Levkin , Ralf Mikut , Markus Reischl

Over the past decade, machine learning model complexity has grown at an extraordinary rate, as has the scale of the systems training such large models. However there is an alarmingly low hardware utilization (5-20%) in large scale AI…

Hardware Architecture · Computer Science 2022-11-14 Newsha Ardalani , Saptadeep Pal , Puneet Gupta

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Shilpa Choudhary , Sandeep Kumar , Pammi Sri Siddhaarth , Guntu Charitasri

Motivation: Innovative microfluidic systems carry the promise to greatly facilitate spatio-temporal analysis of single cells under well-defined environmental conditions, allowing novel insights into population heterogeneity and opening new…

Machine Learning · Computer Science 2021-05-18 Dominik Stallmann , Jan P. Göpfert , Julian Schmitz , Alexander Grünberger , Barbara Hammer

In pulmonary tracheal segmentation, the scarcity of annotated data is a prevalent issue in medical segmentation. Additionally, Deep Learning (DL) methods face challenges: the opacity of 'black box' models and the need for performance…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Shiyi Wang , Yang Nan , Sheng Zhang , Federico Felder , Xiaodan Xing , Yingying Fang , Javier Del Ser , Simon L F Walsh , Guang Yang

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

Introduction: For supervised deep learning (DL) tasks, researchers need a large annotated dataset. In medical data science, one of the major limitations to develop DL models is the lack of annotated examples in large quantity. This is most…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jonathan Fhima , Jan Van Eijgen , Moti Freiman , Ingeborg Stalmans , Joachim A. Behar

Adaptive medical AI models often face performance drops in dynamic clinical environments due to data drift. We propose an autonomous continuous monitoring and data integration framework that maintains robust performance over time. Focusing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Mohammad Daouk , Jan Ulrich Becker , Neeraja Kambham , Anthony Chang , Chandra Mohan , Hien Van Nguyen

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

The dependence on expert annotation has long constituted the primary rate-limiting step in the application of artificial intelligence to biomedicine. While supervised learning drove the initial wave of clinical algorithms, a paradigm shift…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Soumick Chatterjee

Image segmentation and classification are the two main fundamental steps in pattern recognition. To perform medical image segmentation or classification with deep learning models, it requires training on large image dataset with annotation.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-17 Anandhanarayanan Kamalakannan , Shiva Shankar Ganesan , Govindaraj Rajamanickam

Insects comprise millions of species, many experiencing severe population declines under environmental and habitat changes. High-throughput approaches are crucial for accelerating our understanding of insect diversity, with DNA barcoding…

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

Semantic segmentation is crucial for various biomedical applications, yet its reliance on large annotated datasets presents a bottleneck due to the high cost and specialized expertise required for manual labeling. Active Learning (AL) aims…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Carsten T. Lüth , Jeremias Traub , Kim-Celine Kahl , Till J. Bungert , Lukas Klein , Lars Krämer , Paul F. Jaeger , Fabian Isensee , Klaus Maier-Hein

Deep learning has brought the most profound contribution towards biomedical image segmentation to automate the process of delineation in medical imaging. To accomplish such task, the models are required to be trained using huge amount of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Narinder Singh Punn , Sonali Agarwal

Image annotation is one of the most essential tasks for guaranteeing proper treatment for patients and tracking progress over the course of therapy in the field of medical imaging and disease diagnosis. However, manually annotating a lot of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Md Abdul Kadir , Hasan Md Tusfiqur Alam , Pascale Maul , Hans-Jürgen Profitlich , Moritz Wolf , Daniel Sonntag