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Generation of realistic synthetic data has garnered considerable attention in recent years, particularly in the health research domain due to its utility in, for instance, sharing data while protecting patient privacy or determining optimal…

Other Statistics · Statistics 2025-01-30 Niki Z. Petrakos , Erica E. M. Moodie , Nicolas Savy

Simulation especially real-time simulation have been widely used for the design and testing of real-time systems. The advancement of simulation tools has largely attributed to the evolution of computing technologies. With the reduced cost…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-07 Xi Zheng

Time-series learning is the bread and butter of data-driven *clinical decision support*, and the recent explosion in ML research has demonstrated great potential in various healthcare settings. At the same time, medical time-series problems…

Machine Learning · Computer Science 2023-10-31 Daniel Jarrett , Jinsung Yoon , Ioana Bica , Zhaozhi Qian , Ari Ercole , Mihaela van der Schaar

Electronic health records (EHR) systems contain vast amounts of medical information about patients. These data can be used to train machine learning models that can predict health status, as well as to help prevent future diseases or…

Machine Learning · Computer Science 2019-12-25 Mohamed Baza , Andrew Salazar , Mohamed Mahmoud , Mohamed Abdallah , Kemal Akkaya

The reliability of medical LLM evaluation is critically undermined by data contamination and knowledge obsolescence, leading to inflated scores on static benchmarks. To address these challenges, we introduce LiveClin, a live benchmark…

Machine Learning · Computer Science 2026-02-20 Xidong Wang , Shuqi Guo , Yue Shen , Junying Chen , Jian Wang , Jinjie Gu , Ping Zhang , Lei Liu , Benyou Wang

Understanding the latent processes from Electronic Medical Records could be a game changer in modern healthcare. However, the processes are complex due to the interaction between at least three dynamic components: the illness, the care and…

Machine Learning · Computer Science 2017-11-23 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

The increasing demand for mental health services has outpaced the availability of real training data to develop clinical professionals, leading to limited support for the diagnosis of depression. This shortage has motivated the development…

Computation and Language · Computer Science 2025-08-07 Xi Wang , Anxo Perez , Javier Parapar , Fabio Crestani

Clinical case reports encode temporal patient trajectories that are often underexploited by traditional machine learning methods relying on structured data. In this work, we introduce the forecasting problem from textual time series, where…

Computation and Language · Computer Science 2025-12-30 Shahriar Noroozizadeh , Sayantan Kumar , Jeremy C. Weiss

Faced with the challenges of patient confidentiality and scientific reproducibility, research on machine learning for health is turning towards the conception of synthetic medical databases. This article presents a brief overview of…

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is…

Applications · Statistics 2026-01-01 Xin Gai , Shiyi Jiang , Anru R. Zhang

Foundation models hold significant promise in healthcare, given their capacity to extract meaningful representations independent of downstream tasks. This property has enabled state-of-the-art performance across several clinical…

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

Machine Learning · Computer Science 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Patients often struggle to communicate coherent accounts of their health histories during time-constrained clinical encounters. These accounts, which we refer to as health stories, include both clinical events and lived experiences.…

Human-Computer Interaction · Computer Science 2026-05-21 Ryan Smith , Kyle D. Chin , Tamara Munzner

Dynamic treatment regimes have been proposed to personalize treatment decisions by utilizing historical patient data, but they may not always improve on the current standard of care. It is thus meaningful to integrate the standard of care…

Applications · Statistics 2025-12-11 Johannes Hruza , Arvid Sjölander , Erin Gabriel , Samir Bhatt , Michael Sachs

Modeling policies for sequential clinical decision-making based on observational data is useful for describing treatment practices, standardizing frequent patterns in treatment, and evaluating alternative policies. For each task, it is…

Machine Learning · Computer Science 2024-12-12 Anton Matsson , Lena Stempfle , Yaochen Rao , Zachary R. Margolin , Heather J. Litman , Fredrik D. Johansson