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We derive a set of design requirements that lead to structures suitable for molecular circular dichroism (CD) enhancement. Achirality of the structure and two suitably selected sequentially incident beams of opposite helicity ensures that…

Circular dichroism (CD) is absorption difference of right-hand and left-hand circularly polarized light by components. CD spectroscopy technique is an important tool for detecting molecular chirality, but the molecular circular dichroism…

The near-field interaction of plasmonic nanostructures and chiral molecules induces circular dichroism in achiral nanostructure. The induced circular dichroism (ICD) strength is several orders greater than the molecular inherent CD (MCD),…

Circular dichroism (CD) induced by spin angular momentum of light is vital to investigate the chirality of microscopic objects such as molecules, proteins and metamaterials. However, orbital angular momentum (OAM) of light failed to…

Increasing the sensitivity of chiral spectroscopic techniques such as circular dichroism (CD) spectroscopy is a current aspiration in the research field of nanophotonics. Enhancing CD spectroscopy depends upon of two complementary…

In the close vicinity of a chiral nanostructure, the circular dichroism of a biomolecule could be greatly enhanced, due to the interaction with the local superchiral fields. Modest enhancement of optical activity using a planar…

Investigating chiral light-matter interactions is essential for advancing applications in sensing, imaging, and pharmaceutical development. However, the chiroptical response in natural chiral molecules and subwavelength chiral structures is…

Recently, chiral structured illumination microscopy has been proposed to image fluorescent chiral domains at sub-wavelength resolution. Chiral structured illumination microscopy is based on the combination of structured illumination…

Optics · Physics 2021-07-28 Shiang-Yu Huang , Ankit Kumar Singh , Jer-Shing Huang

Chiral response is of tremendous importance to many fields, such as analytical chemistry, polarization manipulation and biological sensing. Here, a chiral metasurface based on rectangular holes is systematically investigated. The results…

Optics · Physics 2021-12-07 Biyuan Wu , Mingjun Wang , Yasong Sun , Feng Wu , Zhangxing Shi , Xiaohu Wu

The measurement of circular dichroism (CD) has widely been exploited to distinguish the different enantiomers of chiral structures. It has been applied to natural materials (e.g. molecules) as well as to artificial materials (e.g.…

Circular dichroism (CD) is an intriguing chiroptical phenomenon associated with the interaction of chiral structures with circularly polarized lights. Although the CD effect has been extensively studied in optics, it has not yet been…

Applied Physics · Physics 2023-06-21 Qing Tong , Jensen Li , Shubo Wang

The controlled fabrication and chiroptical characterization of microscale chiral structures remain central challenges in photonics, sensing, and metamaterial engineering. Here we demonstrate an accessible, low-cost platform that combines…

Optics · Physics 2026-05-07 Jing Xu , Rik Strobbe , Yovan de Coene , Renaud A. L. Vallée , Koen Clays

We present a rigorous finite element method to calculate circular dichroism (CD) in various systems consisting of nanostructures and oriented chiral molecules with electric quadrupole transitions. The interaction between oriented molecule…

Optics · Physics 2017-12-27 Weixuan Zhang , Tong Wu , Rongyao Wang , Xiangdong Zhang

Circular dichroism, arising from interactions with light fields of opposite spin angular momentum, has become a fundamental tool for molecular characterization. Meanwhile, helical dichroism (HD) - the dichroic response to vortex beams…

Chirality, a fundamental concept describing an object cannot superpose with its mirror image, is crucial in optics and photonics and leads to various exotic phenomena, such as circular dichroism, and optical activity. Recent findings reveal…

Optics · Physics 2025-01-13 Shijie Kang , Haitao Li , Jiayu Fan , Jiusi Yu , Boyang Qu , Peng Chen , Xiaoxiao Wu

Chirality is a structural property of molecules lacking mirror symmetry that has strong implications in diverse fields, ranging from life to materials sciences. Established spectroscopic methods that are sensitive to chirality, such as…

The differential response of chiral molecules to incident left- and right- handed circularly polarized light is used for sensing the handedness of molecules. Currently, significant effort is directed towards enhancing weak differential…

Large optical chirality in the vicinity of achiral high index dielectric nanostructures has been recently demonstrated as useful means of enhancing molecular circular dichroism. We theoretically study the spatial dependence of optical…

Optics · Physics 2022-05-25 Krzysztof M. Czajkowski , Tomasz J. Antosiewicz

The interaction between chiral molecules and circularly polarized light is largely influenced by the local optical chirality density. This interaction prompts substantial demand of the design of nanophotonic platforms capable of enhancing…

Optics · Physics 2025-09-30 Guillermo Serrera , Javier González-Colsa , Pablo Albella

Molecular chirality, a form of stereochemistry most often describing relative spatial arrangements of bonded neighbors around tetrahedral carbon centers, influences the set of 3D conformers accessible to the molecule without changing its 2D…

Machine Learning · Computer Science 2021-10-12 Keir Adams , Lagnajit Pattanaik , Connor W. Coley
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