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Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Medical Physics · Physics 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

In patients with obstructive coronary artery disease, the functional significance of a coronary artery stenosis needs to be determined to guide treatment. This is typically established through fractional flow reserve (FFR) measurement,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Majd Zreik , Robbert W. van Hamersvelt , Nadieh Khalili , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Accurate prediction of rarefied gas dynamics is crucial for optimizing flows through microelectromechanical systems, air filtration devices, and shale gas extraction. Traditional methods, such as discrete velocity and direct simulation…

Computational Physics · Physics 2025-01-24 Jean-Michel Tucny , Marco Lauricella , Mihir Durve , Gianmarco Guglielmo , Andrea Montessori , Sauro Succi

Cardiac diseases are one of the leading mortality factors in modern, industrialized societies, which cause high expenses in public health systems. Due to high costs, developing analytical methods to improve cardiac diagnostics is essential.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-19 Bekir Yavuz Koc , Taner Arsan , Onder Pekcan

Unsupervised pathology detection can be implemented by training a model on healthy data only and measuring the deviation from the training set upon inference, for example with CNN-based feature extraction and one-class classifiers, or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Aissam Djahnine , Alexandre Popoff , Emilien Jupin-Delevaux , Vincent Cottin , Olivier Nempont , Loic Boussel

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

Simulations of coronary hemodynamics have improved non-invasive clinical risk stratification and treatment outcomes for coronary artery disease, compared to relying on anatomical imaging alone. However, simulations typically use empirical…

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

Machine Learning · Computer Science 2026-03-17 Irem Topal , Alexander Cherevko , Yuri Bugay , Maxim Shishlenin , Jean Barbier , Deniz Eroglu , Édgar Roldán , Roman Belousov

Simulating complex physical systems is crucial for understanding and predicting phenomena across diverse fields, such as fluid dynamics and heat transfer, as well as plasma physics and structural mechanics. Traditional approaches rely on…

To decrease patient waiting time for diagnosis of the Coronary Artery Disease, automatic methods are applied to identify its severity using Coronary Computed Tomography Angiography scans or extracted Multiplanar Reconstruction (MPR) images,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Mariia Dobko , Bohdan Petryshak , Oles Dobosevych

Background: Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and dangerous pulmonary diseases in the world. It is forecasted that COPD will be the third deadly disease in the future. Therefore, developing…

Medical Physics · Physics 2016-05-30 Mohammad-Parsa Hosseini , Hamid Soltanian-Zadeh , Shahram Akhlaghpoor

The diagnosis of heart diseases is a difficult task generally addressed by an appropriate examination of patients clinical data. Recently, the use of heart rate variability (HRV) analysis as well as of some machine learning algorithms, has…

Kidney stone disease results in millions of annual visits to emergency departments in the United States. Computed tomography (CT) scans serve as the standard imaging modality for efficient detection of kidney stones. Various approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-08-02 Fangyijie Wang , Guenole Silvestre , Kathleen M. Curran

Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Intracranial hemorrhage (ICH) refers to the leakage or accumulation of blood within the skull, which occurs due to the rupture of blood vessels in or around the brain. If this condition is not diagnosed in a timely manner and appropriately…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Mehdi Hosseini Chagahi , Niloufar Delfan , Behzad Moshiri , Md. Jalil Piran , Jaber Hatam Parikhan

Cardiovascular disease is one of the most challenging diseases in middle-aged and older people, which causes high mortality. Coronary artery disease (CAD) is known as a common cardiovascular disease. A standard clinical tool for diagnosing…

Intracranial pressure (ICP) elevation poses severe threats to cerebral function, thus necessitating monitoring for timely intervention. While lumbar puncture is the gold standard for ICP measurement, its invasiveness and associated risks…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Pengxu Wen , Tingting Yu , Ziwei Nie , Cheng Jiang , Zhenyu Yin , Mingyang He , Bo Liao , Xiaoping Yang

Cardiovascular diseases are among the most important causes of global mortality. Computational Fluid Dynamics (CFD) is a powerful research tool that analyzes the hemodynamics of artery and blood flow patterns. In this study, CFD simulations…

Fluid Dynamics · Physics 2023-09-12 Osman Aycan , Adnan Topuz , Lyes Kadem

This paper studies the problem of detecting and segmenting acute intracranial hemorrhage on head computed tomography (CT) scans. We propose to solve both tasks as a semantic segmentation problem using a patch-based fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Weicheng Kuo , Christian Häne , Esther Yuh , Pratik Mukherjee , Jitendra Malik