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Machine learning applications in protein sciences have ushered in a new era for designing molecules in silico. Antibodies, which currently form the largest group of biologics in clinical use, stand to benefit greatly from this shift.…

The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…

Populations and Evolution · Quantitative Biology 2015-05-11 Connor O. McCoy , Trevor Bedford , Vladimir N. Minin , Philip Bradley , Harlan Robins , Frederick A. Matsen

While contemporary large language models (LLMs) are increasingly capable in isolation, there are still many difficult problems that lie beyond the abilities of a single LLM. For such tasks, there is still uncertainty about how best to take…

Artificial Intelligence · Computer Science 2026-02-27 Ryan Liu , Dilip Arumugam , Cedegao E. Zhang , Sean Escola , Xaq Pitkow , Thomas L. Griffiths

Artificial Intelligence (AI) is revolutionizing emergency medicine by enhancing diagnostic processes and improving patient outcomes. This article provides a review of the current applications of AI in emergency imaging studies, focusing on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Gustavo Correia , Victor Alves , Paulo Novais

Recent advances in diffusion models have shown remarkable potential for antibody design, yet existing approaches apply uniform generation strategies that cannot adapt to each antigen's unique requirements. Inspired by B cell affinity…

Machine Learning · Computer Science 2025-08-19 Hanqi Feng , Peng Qiu , Mengchun Zhang , Yiran Tao , You Fan , Jingtao Xu , Barnabas Poczos

Precision medicine, tailored to individual patients based on their genetics, environment, and lifestyle, shows promise in managing complex diseases like infections. Integrating artificial intelligence (AI) into precision medicine can…

Other Quantitative Biology · Quantitative Biology 2023-07-31 Ghizal fatima , Risala H. Allami , Maitham G. Yousif

Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu

The rapid evolution of Artificial Intelligence (AI) has significantly transformed healthcare, particularly in the domain of Remote Patient Monitoring (RPM). This chapter explores the integration of AI in RPM, highlighting real-life…

Human-Computer Interaction · Computer Science 2024-07-26 Nishargo Nigar

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

Artificial Intelligence (AI) has demonstrated unprecedented performance across various domains, and its application to communication systems is an active area of research. While current methods focus on task-specific solutions, the broader…

Artificial Intelligence · Computer Science 2025-05-21 Davide Buffelli , Sowmen Das , Yu-Wei Lin , Sattar Vakili , Chien-Yi Wang , Masoud Attarifar , Pritthijit Nath , Da-shan Shiu

Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse folding, and biomolecular interaction modeling. However, the…

Machine Learning · Computer Science 2026-03-30 Senura Hansaja Wanasekara , Minh-Duong Nguyen , Xiaochen Liu , Nguyen H. Tran , Ken-Tye Yong

The anticipated integration of large artificial intelligence (AI) models with wireless communications is estimated to usher a transformative wave in the forthcoming information age. As wireless networks grow in complexity, the traditional…

Information Theory · Computer Science 2026-01-13 Chong Huang , Gaojie Chen , Pei Xiao , Zhu Han , Rahim Tafazolli

Applications of artificial intelligence (AI) in drug development continue to increase at a rapid pace. Regulatory authorities have provided increasingly clear perspectives on the use of AI in regulated applications, including recent draft…

Applications · Statistics 2026-05-25 Aaron M. Smith , Tala Fakhouri , Run Zhuang , Jonathan R. Walsh

Lung cancer remains one of the most prevalent and fatal diseases worldwide, demanding accurate and timely diagnosis and treatment. Recent advancements in large AI models have significantly enhanced medical image understanding and clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Jiachen Zhong , Yiting Wang , Di Zhu , Ziwei Wang

Artificial intelligence (AI) systems are becoming critical components of today's IT landscapes. Their resilience against attacks and other environmental influences needs to be ensured just like for other IT assets. Considering the…

As AI adoption expands across human society, the problem of aligning AI models to match human preferences remains a grand challenge. Currently, the AI alignment field is deeply divided between behavioral and representational approaches,…

Computers and Society · Computer Science 2025-08-12 Ben Y. Reis , William La Cava

Artificial Intelligence (AI) and infectious diseases prediction have recently experienced a common development and advancement. Machine learning (ML) apparition, along with deep learning (DL) emergence, extended many approaches against…

Machine Learning · Computer Science 2025-01-29 Selestine Melchane , Youssef Elmir , Farid Kacimi , Larbi Boubchir

The last decade has seen tremendous progress in AI technology and applications. With such widespread adoption, ensuring the reliability of the AI models is crucial. In past, we took the first step of creating a testing framework called…

Artificial Intelligence · Computer Science 2021-10-08 Swagatam Haldar , Deepak Vijaykeerthy , Diptikalyan Saha

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

Artificial Intelligence models are becoming increasingly more powerful and accurate, supporting or even replacing humans' decision making. But with increased power and accuracy also comes higher complexity, making it hard for users to…

Artificial Intelligence · Computer Science 2019-07-10 Vivian S. Silva , André Freitas , Siegfried Handschuh