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Accurate lesion segmentation in histopathology images is essential for diagnostic interpretation and quantitative analysis, yet it remains challenging due to the limited availability of costly pixel-level annotations. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hangbei Cheng , Xiaorong Dong , Xueyu Liu , Jianan Zhang , Xuetao Ma , Mingqiang Wei , Liansheng Wang , Junxin Chen , Yongfei Wu

State Space Models (SSMs), especially Mamba, have shown great promise in medical image segmentation due to their ability to model long-range dependencies with linear computational complexity. However, accurate medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Chaowei Chen , Li Yu , Shiquan Min , Shunfang Wang

High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Anghong Du , Nay Aung , Theodoros N. Arvanitis , Stefan K. Piechnik , Joao A C Lima , Steffen E. Petersen , Le Zhang

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

In data-scarce scenarios, deep learning models often overfit to noise and irrelevant patterns, which limits their ability to generalize to unseen samples. To address these challenges in medical image segmentation, we introduce Diff-UMamba,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Dhruv Jain , Romain Modzelewski , Romain Herault , Clement Chatelain , Eva Torfeh , Sebastien Thureau

Semantic image segmentation is one of fastest growing areas in computer vision with a variety of applications. In many areas, such as robotics and autonomous vehicles, semantic image segmentation is crucial, since it provides the necessary…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Georgios Takos

Medical image segmentation requires balancing local precision for boundary-critical clinical applications, global context for anatomical coherence, and computational efficiency for deployment on limited data and hardware a trilemma that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Md. Sanaullah Chowdhury Lameya Sabrin

Recent advances of semantic image segmentation greatly benefit from deeper and larger Convolutional Neural Network (CNN) models. Compared to image segmentation in the wild, properties of both medical images themselves and of existing…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Xin Chen , Ke Ding

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Medical image segmentation has become an essential technique in clinical and research-oriented applications. Because manual segmentation methods are tedious, and fully automatic segmentation lacks the flexibility of human intervention or…

Image and Video Processing · Electrical Eng. & Systems 2019-04-24 Kevin Karsch , Qing He , Ye Duan

Image segmentation is often performed on medical images for identifying diseases in clinical evaluation. Hence it has become one of the major research areas. Conventional image segmentation techniques are unable to provide satisfactory…

Computer Vision and Pattern Recognition · Computer Science 2017-02-13 Pratik Kalshetti , Manas Bundele , Parag Rahangdale , Dinesh Jangra , Chiranjoy Chattopadhyay , Gaurav Harit , Abhay Elhence

Masked image modeling (MIM) with transformer backbones has recently been exploited as a powerful self-supervised pre-training technique. The existing MIM methods adopt the strategy to mask random patches of the image and reconstruct the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Zhaohu Xing , Lei Zhu , Lequan Yu , Zhiheng Xing , Liang Wan

Recent works have shown that the computational efficiency of 3D medical image (e.g. CT and MRI) segmentation can be impressively improved by dynamic inference based on slice-wise complexity. As a pioneering work, a dynamic architecture…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Haoran Shen , Yifu Zhang , Wenxuan Wang , Chen Chen , Jing Liu , Shanshan Song , Jiangyun Li

Automated medical image segmentation can assist doctors to diagnose faster and more accurate. Deep learning based models for medical image segmentation have made great progress in recent years. However, the existing models fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Lei Shi , Tianyu Gao , Zheng Zhang , Junxing Zhang

Training medical image segmentation models for rare yet clinically important imaging modalities is challenging due to the scarcity of annotated data, and manual mask annotations can be costly and labor-intensive to acquire. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Haoning Wu , Ziheng Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Obtaining pixel-level annotations in the medical domain is both expensive and time-consuming, often requiring close collaboration between clinical experts and developers. Semi-supervised medical image segmentation aims to leverage limited…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Lin Xi , Yingliang Ma , Cheng Wang , Sandra Howell , Aldo Rinaldi , Kawal S. Rhode

Due to the high cost of annotation or the rarity of some diseases, medical image segmentation is often limited by data scarcity and the resulting overfitting problem. Self-supervised learning and semi-supervised learning can mitigate the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Danyang Sun , Fadi Dornaika , Nagore Barrena
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