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Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

Machine Learning · Computer Science 2025-05-01 Erica Chiang , Divya Shanmugam , Ashley N. Beecy , Gabriel Sayer , Deborah Estrin , Nikhil Garg , Emma Pierson

The association between multidimensional exposure patterns and outcomes is commonly investigated by first applying cluster analysis algorithms to derive patterns and then estimating the associations. However, errors in the underlying…

Methodology · Statistics 2023-05-31 Timm Intemann , Iris Pigeot

Motivated by environmental policy questions, we address the challenges of estimation, change point detection, and uncertainty quantification of a causal exposure-response function (CERF). Under a potential outcome framework, the CERF…

Methodology · Statistics 2023-01-27 Boyu Ren , Xiao Wu , Danielle Braun , Natesh Pillai , Francesca Dominici

We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…

Machine Learning · Statistics 2019-02-07 Hao Wang , Chengzhi Mao , Hao He , Mingmin Zhao , Tommi S. Jaakkola , Dina Katabi

Estimating how a treatment affects units individually, known as heterogeneous treatment effect (HTE) estimation, is an essential part of decision-making and policy implementation. The accumulation of large amounts of data in many domains,…

Machine Learning · Computer Science 2022-06-28 Christopher Tran , Elena Zheleva

Bayesian Causal Forests (BCF) is a causal inference machine learning model based on a highly flexible non-parametric regression and classification tool called Bayesian Additive Regression Trees (BART). Motivated by data from the Trends in…

Machine Learning · Statistics 2023-03-10 Nathan McJames , Andrew Parnell , Yong Chen Goh , Ann O'Shea

Estimating risk factors for incidence of a disease is crucial for understanding its etiology. For diseases caused by enteric pathogens, off-the-shelf statistical model-based approaches do not consider the biological mechanisms through which…

Methodology · Statistics 2024-10-25 Daniel K. Sewell , Kelly K. Baker

Data scarcity is a tremendous challenge in causal effect estimation. In this paper, we propose to exploit additional data sources to facilitate estimating causal effects in the target population. Specifically, we leverage additional source…

Machine Learning · Computer Science 2021-06-01 Thanh Vinh Vo , Pengfei Wei , Trong Nghia Hoang , Tze-Yun Leong

Obesity is a major health problem, increasing the risk of various major chronic diseases, such as diabetes, cancer, and stroke. While the role of obesity identified by cross-sectional BMI recordings has been heavily studied, the role of BMI…

Machine Learning · Computer Science 2024-12-03 Md Mozaharul Mottalib , Jessica C Jones-Smith , Bethany Sheridan , Rahmatollah Beheshti

We present an approach to estimate distance-dependent heterogeneous associations between point-referenced exposures to built environment characteristics and health outcomes. By estimating associations that depend non-linearly on distance…

Methodology · Statistics 2021-07-14 Adam Peterson , Emma Sanchez-Vaznaugh , Brisa Sanchez

Built environment features (BEFs) refer to aspects of the human constructed environment, which may in turn support or restrict health related behaviors and thus impact health. In this paper we are interested in understanding whether the…

Applications · Statistics 2020-10-16 Adam Peterson , Veronica Berrocal , Emma Sanchez-Vaznaugh , Brisa Sanchez

In causal estimation problems, the parameter of interest is often only partially identified, implying that the parameter cannot be recovered exactly, even with infinite data. Here, we study Bayesian inference for partially identified…

Methodology · Statistics 2022-04-26 Jiajing Zheng , Alexander D'Amour , Alexander Franks

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Image-based dietary assessment refers to the process of determining what someone eats and how much energy and nutrients are consumed from visual data. Food classification is the first and most crucial step. Existing methods focus on…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Runyu Mao , Jiangpeng He , Luotao Lin , Zeman Shao , Heather A. Eicher-Miller , Fengqing Zhu

Artificially sweetened beverages like Diet Coke are often considered better alternatives to sugary drinks, but the debate over their impact on health, particularly in relation to obesity, continues. Previous research has predominantly used…

Computers and Society · Computer Science 2024-08-20 Yicheng Qi , Ang Li

Obesity, the leading cause of many non-communicable diseases, occurs mainly for eating more than our body requirements and lack of proper activity. So, being healthy requires heathy diet plans, especially for patients with comorbidities.…

Machine Learning · Computer Science 2023-08-08 Mrinmoy Roy , Srabonti Das , Anica Tasnim Protity

Gene-gene and gene-environment interactions are widely believed to play significant roles in explaining the variability of complex traits. While substantial research exists in this area, a comprehensive statistical framework that addresses…

Methodology · Statistics 2026-02-18 Durba Bhattacharya , Sourabh Bhattacharya

In this paper, we propose the use of causal inference techniques for survival function estimation and prediction for subgroups of the data, upto individual units. Tree ensemble methods, specifically random forests were modified for this…

Econometrics · Economics 2018-03-23 Vikas Ramachandra

Environmental health researchers may aim to identify exposure patterns that represent sources, product use, or behaviors that give rise to mixtures of potentially harmful environmental chemical exposures. We present Bayesian non-parametric…

Long-running clinical trials offer a unique opportunity to study disease progression and treatment response over time, enabling questions about how and when interventions alter patient trajectories. However, drawing causal conclusions in…

Applications · Statistics 2025-08-13 Emma Prevot , Dieter A. Häring , Thomas E. Nichols , Chris C. Holmes , Habib Ganjgahi
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