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We present a generic framework for describing interacting, spinning, active polar particles, aimed at modelling dense cell aggregates, where cells are treated as polar, rotating objects that interact mechanically with one another and their…

Soft Condensed Matter · Physics 2024-11-01 Quentin Vagne , Guillaume Salbreux

We predict the conditions under which two oppositely charged membranes show a dynamic, attractive instability. Two layers with unequal charges of opposite sign can repel or be stable when in close proximity. However, dynamic charge density…

Soft Condensed Matter · Physics 2009-11-10 Guy Hed , S. A. Safran

Active matter agents consume internal energy or extract energy from the environment for locomotion and force generation. Already rather generic models, such as ensembles of active Brownian particles, exhibit phenomena, which are absent at…

Soft Condensed Matter · Physics 2020-07-27 Roland G. Winkler , Gerhard Gompper

We investigate theoretically the collective dynamics of soft active particles living in a viscous fluid. We focus on a minimal model for active but non-motile particles consisting of $N>1$ elastic dimers deformed by active stresses and…

Soft Condensed Matter · Physics 2010-04-09 Denis Bartolo , Eric Lauga

Dense, active systems show active turbulence, a state characterised by flow fields that are chaotic, with continually changing velocity jets and swirls. Here we review our current understanding of active turbulence. The development is…

Soft Condensed Matter · Physics 2016-08-03 Sumesh P. Thampi , Julia M. Yeomans

Within the framework of mode-coupling theory, we present a simple model for describing dense assemblies of active (self-propelled) spherical colloidal particles. For isotropic suspensions, we demonstrate that the glass transition is shifted…

Soft Condensed Matter · Physics 2014-03-10 T. F. F. Farage , J. M. Brader

Advances in nanotechnology lead to an increasing interest in how nanoparticles interact with biomembranes. Nanoparticles are wrapped spontaneously by biomembranes if the adhesive interactions between the particles and membranes compensate…

Subcellular Processes · Quantitative Biology 2016-09-16 Michael Raatz , Thomas R. Weikl

Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

Soft Condensed Matter · Physics 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

The purpose of this work is to use active particles to study the effect of facilitation on supercooled liquids. To this end we investigate the behavior of a model supercooled liquid doped with intermittently active and intermittently slowed…

Soft Condensed Matter · Physics 2023-08-11 Victor Teboul

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Active particles driven by colored noise can be approximately mapped onto a system that obeys detailed balance. The effective interactions which can be derived for such a system allow to describe the structure and phase behavior of the…

Soft Condensed Matter · Physics 2017-11-30 René Wittmann , Umberto Marini Bettolo Marconi , Claudio Maggi , Joseph M. Brader

We consider two minimal models of active fluid droplets that exhibit complex dynamics including steady motion, deformation, rotation and oscillating motion. First we consider a droplet with a concentration of active contractile matter…

Soft Condensed Matter · Physics 2016-12-20 Carl A. Whitfield , Rhoda J. Hawkins

We study the interplay of activity, order and flow through a set of coarse-grained equations governing the hydrodynamic velocity, concentration and stress fields in a suspension of active, energy-dissipating particles. We make several…

Soft Condensed Matter · Physics 2009-11-10 Yashodhan Hatwalne , Sriram Ramaswamy , Madan Rao , R. Aditi Simha

The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that…

Soft Condensed Matter · Physics 2023-08-15 Ioannis Hadjifrangiskou , Liam J. Ruske , Julia M. Yeomans

In simulations, particles are traditionally treated as rigid platforms with variable sizes, shapes and interaction parameters. While this representation is applicable for rigid core platforms, particles consisting of soft platforms (e.g.…

Soft Condensed Matter · Physics 2024-08-06 Massimiliano Paesani , Ioana M. Ilie

We explore the pressure of active particles on curved surfaces and its relation to other interfacial properties. We use both direct simulations of the active systems as well as simulations of an equilibrium system with effective (pair)…

Soft Condensed Matter · Physics 2019-05-14 René Wittmann , Frank Smallenburg , Joseph M. Brader

We derive a fully covariant theory of the mechanics of active surfaces. This theory provides a framework for the study of active biological or chemical processes at surfaces, such as the cell cortex, the mechanics of epithelial tissues, or…

Biological Physics · Physics 2017-09-13 Guillaume Salbreux , Frank Jülicher

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

A flexible membrane deforming its shape in time can self-propel in a viscous fluid. Alternatively, if the membrane is anchored, its deformation will lead to fluid transport. Past work in this area focused on situations where the deformation…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Eric Lauga

Soft, amorphous solids such as tissues, foams, and emulsions are composed of deformable particles. However, the effect of single-particle deformability on the collective behavior of soft solids is still poorly understood. We perform…

Soft Condensed Matter · Physics 2021-06-02 John D. Treado , Dong Wang , Arman Boromand , Michael P. Murrell , Mark D. Shattuck , Corey S. O'Hern