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We present the Agentic AI Detection and Response (ADR) system, the first large-scale, production-proven enterprise framework for securing AI agents operating through the Model Context Protocol (MCP). We identify three persistent challenges…

Artificial Intelligence · Computer Science 2026-05-19 Chenning Li , Pan Hu , Justin Xu , Baris Ozbas , Olivia Liu , Caroline Van , Manxue Li , Wei Zhou , Mohammad Alizadeh , Pengyu Zhang , KK Sriramadhesikan , Ming Zhang

We present Portable Agent Memory, an open protocol and reference implementation for transferring persistent memory state across heterogeneous AI agents. Modern AI agents accumulate rich context -- episodic events,semantic knowledge,…

Cryptography and Security · Computer Science 2026-05-13 Santhosh Kumar Ravindran

Agent-based modeling (ABM) provides a powerful framework for exploring how individual behaviors and interactions give rise to collective social dynamics. However, most ABMs rely on handcrafted or parameterized agent rules that are not…

Social and Information Networks · Computer Science 2026-01-21 Abdul Sittar , Miha Cesnovar , Alenka Gucek , Marko Grobelnik

In this paper, we outline a framework for modeling utility-based blockchain-enabled economic systems using Agent Based Modeling (ABM). Our approach is to model the supply dynamics based on metrics of the cryptoeconomy. We then build…

Cryptography and Security · Computer Science 2023-07-31 Kiran Karra , Tom Mellan , Maria Silva , Juan P. Madrigal-Cianci , Axel Cubero Cortes , Zixuan Zhang

An agent-based model (ABM) is a computational model in which the local interactions of autonomous agents with each other and with their environment give rise to global properties within a given domain. As the detail and complexity of these…

Dynamical Systems · Mathematics 2022-12-01 Daniel A. Cruz , Jack Toppen , Eunbi Park , Melissa L. Kemp , Elena S. Dimitrova

This paper presents CPEMH, an agentic framework designed to evaluate prompt-driven behavior in foundation-model systems operating on transcript-based datasets for mental-health screening. CPEMH serves as an engineering methodology for…

Artificial Intelligence · Computer Science 2026-05-13 Giuliano Lorenzoni , Ivens Portugal , Paulo Alencar , Donald Cowan

Background: Many biological systems are modeled qualitatively with discrete models, such as probabilistic Boolean networks, logical models, Petri nets, and agent-based models, with the goal to gain a better understanding of the system. The…

Emerging infectious diseases and climate change are two of the major challenges in 21st century. Although over the past decades, highly-resolved mathematical models have contributed in understanding dynamics of infectious diseases and are…

Populations and Evolution · Quantitative Biology 2025-10-13 Julia Bicker , René Schmieding , Michael Meyer-Hermann , Martin J. Kühn

Autonomous agents are moving from tools into a layer of social infrastructure: they browse, purchase, deploy software, manage systems, and increasingly interact with one another. As these systems scale, the bottleneck shifts away from raw…

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Agent-based models (ABMs) simulate interactions between autonomous agents in constrained environments over time. ABMs are often used for modeling the spread of infectious diseases. In order to simulate disease outbreaks or other phenomena,…

Other Statistics · Statistics 2017-01-11 Shannon Gallagher , Lee Richardson , Samuel L. Ventura , William F. Eddy

While large language model (LLM) multi-agent systems achieve superior reasoning performance through iterative debate, practical deployment is limited by their high computational cost and error propagation. This paper proposes AgentArk, a…

Artificial Intelligence · Computer Science 2026-05-26 Yinyi Luo , Yiqiao Jin , Weichen Yu , Mengqi Zhang , Srijan Kumar , Xiaoxiao Li , Weijie Xu , Xin Chen , Jindong Wang

Agentic workflows in large language model systems integrate retrieval, reasoning, and memory, but existing frameworks suffer from scalability and reproducibility limitations due to fragmented data orchestration, serialization overhead, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-05 Arup Kumar Sarker , Mills Staylor , Aymen Alsaadi , Gregor von Laszewski , Shantenu Jha , Geoffrey Fox

This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

In recent years, dynamic agent-based population models, which model every inhabitant of a country as a statistically representative agent, have been gaining in popularity for decision support. This is mainly due to their high degree of…

Multiagent Systems · Computer Science 2025-11-11 Martin Bicher , Maximilian Viehauser , Daniele Giannandrea , Hannah Kastinger , Dominik Brunmeir , Niki Popper

To observe how individual behavior shapes a larger community's actions, agent-based modeling and simulation (ABMS) has been widely adopted by researchers in social sciences, economics, and epidemiology. While simulations can be run on…

Social and Information Networks · Computer Science 2025-07-16 Ann Nedime Nese Rende , Tolga Yilmaz , Özgür Ulusoy

Agent-based simulators (ABS) are a popular epidemiological modelling tool to study the impact of various non-pharmaceutical interventions in managing an epidemic in a city (or a region). They provide the flexibility to accurately model a…

Physics and Society · Physics 2025-10-13 Daksh Mittal , Sandeep Juneja

Autonomous agents powered by large language models (LLMs) perform complex tasks through long-horizon reasoning and tool interaction, where a fundamental trade-off arises between execution efficiency and reasoning robustness. Models at…

Computation and Language · Computer Science 2026-03-30 Wenbo Gao , Renxi Liu , Xian Wang , Fang Guo , Shuai Yang , Xi Chen , Hui-Ling Zhen , Hanting Chen , Weizhe Lin , Xiaosong Li , Yaoyuan Wang

Artificial intelligence and machine learning systems have demonstrated huge improvements and human-level parity in a range of activities, including speech recognition, face recognition and speaker verification. However, these diverse tasks…

Human-Computer Interaction · Computer Science 2019-09-04 Vidhyasaharan Sethu , Emily Mower Provost , Julien Epps , Carlos Busso , Nicholas Cummins , Shrikanth Narayanan

Multi-Agent Experience Replay (MER) is a key component of off-policy reinforcement learning~(RL) algorithms. By remembering and reusing experiences from the past, experience replay significantly improves the stability of RL algorithms and…

Multiagent Systems · Computer Science 2023-06-02 Kailash Gogineni , Yongsheng Mei , Peng Wei , Tian Lan , Guru Venkataramani
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