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We here examine the nonlinear dynamics of artificial homogeneous DNA chain relying on the plain-base rotator model. It is shown that such dynamics can exhibit kink and antikink solitons of sine-Gordon type. In that respect we propose…

Biological Physics · Physics 2015-06-05 S. Zdravković , M. V. Satarić , M. Daniel

A theory is presented of the longitudinal dispersion of DNA under equilibrium confined in a nanochannel. Orientational fluctuations of the DNA chain build up to give rise to substantial fluctuations of the coil in the longitudinal direction…

Soft Condensed Matter · Physics 2009-11-18 Theo Odijk

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

Soft Condensed Matter · Physics 2008-02-03 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

We describe a simple meanfield variational approach to study a number of properties of intrinsically stiff chains which are appropriate models for a large class of biopolymers. We present the calculation of the distribution of end-to-end…

Soft Condensed Matter · Physics 2008-02-03 D. Thirumalai , B. -Y. Ha

Harnessing the topology of ring polymers as a design motif in functional nanomaterials is becoming a promising direction in the field of soft matter. For example, the ring topology of DNA plasmids prevents the relaxation of excess twist…

Soft Condensed Matter · Physics 2026-04-29 Roman Staňo , Renáta Rusková , Dušan Račko , Jan Smrek

The advent of solid state nanodevices allows for interrogating the physico-chemical properties of a polyelectrolyte chain by electrophoretically driving it through a nanopore. Salient dynamical aspects of the translocation process have been…

Soft Condensed Matter · Physics 2015-06-05 A. Rosa , M. Di Ventra , C. Micheletti

The mechanical properties of molecules are today captured by single molecule manipulation experiments, so that polymer features are tested at a nanometric scale. Yet devising mathematical models to get further insight beyond the commonly…

Far from being a passive information store, the genome is a mechanically dynamic and diverse system in which torsion and tension fluctuate and combine to determine structure and help regulate gene expression. Much of this mechanical…

Biomolecules · Quantitative Biology 2021-09-01 Jack W Shepherd , Mark C Leake

Although the stretching of polymers and biomolecules is important in numerous settings, their response when confined to two-dimensions is relatively poorly-studied. In this paper, we derive closed-form analytical expressions for the…

Soft Condensed Matter · Physics 2013-05-28 Sara Iliafar , Dmitri Vezenov , Anand Jagota

Mechanical properties of DNA, in particular their stretch dependent extension and their loop formation characteristics, have been recognized as an effective probe for understanding the possible biochemical role played by them in a living…

Soft Condensed Matter · Physics 2015-06-04 Kulveer Singh , Surya K. Ghosh , Sanjay Kumar , Anirban Sain

We review statistical-mechanical theories of single-molecule micromanipulation experiments on nucleic acids. First, models for describing polymer elasticity are introduced. We then review how these models are used to interpret…

Soft Condensed Matter · Physics 2007-05-23 S. Cocco , J. F. Marko , R. Monasson

Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome formation. Nucleosome disruption under stretching was also…

Biomolecules · Quantitative Biology 2007-05-23 Wei Li , Shuo-Xing Dou , Peng-Ye Wang

The denaturation transition of circular DNA is studied within a Poland-Scheraga type approach, generalized to account for the fact that the total linking number (LK), which measures the number of windings of one strand around the other, is…

Statistical Mechanics · Physics 2015-06-05 Amir Bar , Alkan Kabakçıoğlu , David Mukamel

Overstretching of B-DNA is currently understood as force-induced melting. Depending on the geometry of the stretching experiment, the force threshold for the overstretching transition is around 65 or 110 pN. Although the mechanisms behind…

Biological Physics · Physics 2019-03-06 Nikos Theodorakopoulos

Within a model that supports stripe spin and charge order coexisting with a d$_{x^2-y^2}$-wave superconducting phase, we study the self-consistently obtained electronic structure and the associated transverse dynamical spin susceptibility.…

Superconductivity · Physics 2009-11-10 Brian M. Andersen , Per Hedegard

The elastic properties of semiflexible polymers are of great importance in biology. There are experiments on biopolymers like double stranded DNA, which twist and stretch single molecules to probe their elastic properties. It is known that…

Soft Condensed Matter · Physics 2010-12-01 Supurna Sinha , Joseph Samuel

The interplay between global constraints and local material properties of chain molecules is a subject of emerging interest. Studies of molecules that are intrinsically chiral, such as double-stranded DNA, is one example. Their properties…

Biological Physics · Physics 2013-11-27 Jakob Bohr , Kasper W. Olsen

Mechanical properties of nucleic acids play an important role in many biological processes which often involve physical deformations of these molecules. At sufficiently long length scales (say above $\sim 20-30$ base pairs) the mechanics of…

Statistical Mechanics · Physics 2022-08-12 Midas Segers , Aderik Voorspoels , Takahiro Sakaue , Enrico Carlon

A theoretical framework for evaluating the approximate energy and dynamic properties associated with the folding of DNA into nucleosomes and chromatin is presented. For this purpose experimentally determined elastic constants of linear DNA…

Biological Physics · Physics 2007-05-23 Thomas C. Bishop , Oleksandr O. Zhmudsky

It is well-established that many physical properties of DNA at sufficiently long length scales can be understood by means of simple polymer models. One of the most widely used elasticity models for DNA is the twistable worm-like chain…

Biomolecules · Quantitative Biology 2017-06-12 Enrico Skoruppa , Michiel Laleman , Stefanos Nomidis , Enrico Carlon