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Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Optical coherence tomography (OCT) and photoacoustic tomography (PAT) are emerging non-invasive biological and medical imaging techniques. It is a recent trend in experimental science to design experiments that perform PAT and OCT imaging…

Analysis of PDEs · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Optical diffraction tomography (ODT) is a powerful technique for quantitative, label-free reconstruction of the three-dimensional refractive index (RI) distribution of biological samples. While ODT is well established for imaging thin,…

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Electron tomography is a technique used in both materials science and structural biology to image features well below optical resolution limit. In this work, we present a new algorithm for reconstructing the three-dimensional(3D)…

Signal Processing · Electrical Eng. & Systems 2018-07-12 David Ren , Michael Chen , Laura Waller , Colin Ophus

In this paper, we demonstrate that atom probe tomography (APT) can be applied to small-molecule organic materials. We show that APT can provide an unprecedented combination of mass resolution of $\lt 1~\mathrm{Da}$, spatial resolution of…

In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter. This is particularly important in medical imaging applications, such as…

Optimization and Control · Mathematics 2024-04-12 Guozhi Dong , Moritz Flaschel , Michael Hintermüller , Kostas Papafitsoros , Clemens Sirotenko , Karsten Tabelow

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

The optical diffraction limit, formulated by Abbe 140 years ago, imposes a bound on imaging resolution in classical optics. Over the last twenty years, many theoretical schemes have been presented for overcoming the diffraction barrier in…

Quantum Physics · Physics 2013-07-12 O. Schwartz , J. M. Levitt , R. Tenne , S. Itzhakov , Z. Deutsch , D. Oron

Electrical Impedance Tomography (EIT) is a non-invasive, low-cost bedside imaging modality with high temporal resolution, making it suitable for bedside monitoring. However, its inherently ill-posed inverse problem poses significant…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Hao Fang , Sihao Teng , Hao Yu , Siyi Yuan , Huaiwu He , Zhe Liu , Yunjie Yang

Forward and backward scattering provide complementary volumetric and interfacial information, yet conventional three-dimensional (3D) imaging typically accesses only one. In this Letter, we present a substrate-enhanced diffraction…

Optics · Physics 2026-03-05 Tongyu Li , Yi Shen , Dashan Dong , Danchen Jia , Jianpeng Ao , Ji-Xin Cheng , Lei Tian

We propose a novel approach to the important fundamental problem of detecting weak optical fields at the few photon level. The ability to detect with high efficiency (>99%), and to distinguish the number of photons in a given time interval…

Quantum Physics · Physics 2009-11-07 Daniel James , Paul Kwiat

We report a computational 3D microscopy technique, termed Fourier ptychographic diffraction tomography (FPDT), that iteratively stitches together numerous variably illuminated, low-resolution images acquired with a low-numerical aperture…

Optics · Physics 2020-02-19 Chao Zuo , Jiasong Sun , Jiaji Li , Anand Asundi , Qian Chen

We present an algorithm for coherent diffractive imaging with phaseless measurements. It treats the forward model as a combination of coherent and incoherent waves. The algorithm reconstructs absorption and phase contrast that quantifies…

Computational Physics · Physics 2022-08-25 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

An arbitrary quantum-optical process (channel) can be completely characterized by probing it with coherent states using the recently developed coherent-state quantum process tomography (QPT) [Lobino et al., Science 322, 563 (2008)]. In…

Quantum Physics · Physics 2013-08-09 Xiang-Bin Wang , Zong-Wen Yu , Jia-Zhong Hu , Adam Miranowicz , Franco Nori

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

Instrumentation and Detectors · Physics 2012-02-03 C. Lang , D. Habs , P. G. Thirolf , A. Zoglauer

Existing super-resolution methods of optical imaging hold a solid place as an application in natural sciences, but many new developments allow for beating the diffraction limit in a more subtle way. One of the recently explored strategies…

Quantum Physics · Physics 2022-02-08 Mateusz Mazelanik , Adam Leszczyński , Michał Parniak

Quaternionic signal processing provides powerful tools for efficiently managing color signals by preserving the intrinsic correlations among signal dimensions through quaternion algebra. In this paper, we address the quaternionic phase…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Ren Hu , Pan Lian

Label-free imaging approaches seek to simplify and augment histopathologic assessment by replacing the current practice of staining by dyes to visualize tissue morphology with quantitative optical measurements. Quantitative phase imaging…