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Dynamic contrast-enhanced (DCE) MRI is essential for breast cancer diagnosis and treatment. However, its reliance on contrast agents introduces safety concerns, contraindications, increased cost, and workflow complexity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Sebastian Ibarra , Javier del Riego , Alessandro Catanese , Julian Cuba , Julian Cardona , Nataly Leon , Jonathan Infante , Karim Lekadir , Oliver Diaz , Richard Osuala

Contrast agents in dynamic contrast enhanced magnetic resonance imaging allow to localize tumors and observe their contrast kinetics, which is essential for cancer characterization and respective treatment decision-making. However, contrast…

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sanuwani Dayarathna , Kh Tohidul Islam , Bohan Zhuang , Guang Yang , Jianfei Cai , Meng Law , Zhaolin Chen

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Multi-contrast MRI protocols increase the level of morphological information available for diagnosis. Yet, the number and quality of contrasts is limited in practice by various factors including scan time and patient motion. Synthesis of…

Image and Video Processing · Electrical Eng. & Systems 2019-09-26 Mahmut Yurt , Salman Ul Hassan Dar , Aykut Erdem , Erkut Erdem , Tolga Çukur

We propose a novel approach to translate unpaired contrast computed tomography (CT) scans to non-contrast CT scans and the other way around. Solving this task has two important applications: (i) to automatically generate contrast CT scans…

Non-contrast computed tomography (NCCT) is commonly acquired for lung cancer screening, assessment of general abdominal pain or suspected renal stones, trauma evaluation, and many other indications. However, the absence of contrast limits…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Ho Hin Lee , Yucheng Tang , Riqiang Gao , Qi Yang , Xin Yu , Shunxing Bao , James G. Terry , J. Jeffrey Carr , Yuankai Huo , Bennett A. Landman

Multi-contrast magnetic resonance imaging (MRI) is widely used in clinical practice as each contrast provides complementary information. However, the availability of each imaging contrast may vary amongst patients, which poses challenges to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-31 Jiang Liu , Srivathsa Pasumarthi , Ben Duffy , Enhao Gong , Keshav Datta , Greg Zaharchuk

Despite its benefits for tumour detection and treatment, the administration of contrast agents in dynamic contrast-enhanced MRI (DCE-MRI) is associated with a range of issues, including their invasiveness, bioaccumulation, and a risk of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-03 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Oliver Diaz , Karim Lekadir

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

Multi-contrast MRI acquisitions of an anatomy enrich the magnitude of information available for diagnosis. Yet, excessive scan times associated with additional contrasts may be a limiting factor. Two mainstream approaches for enhanced scan…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Salman Ul Hassan Dar , Mahmut Yurt , Mohammad Shahdloo , Muhammed Emrullah Ildız , Tolga Çukur

Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Alicia Durrer , Julia Wolleb , Florentin Bieder , Tim Sinnecker , Matthias Weigel , Robin Sandkühler , Cristina Granziera , Özgür Yaldizli , Philippe C. Cattin

Magnetic resonance imaging (MRI) is a remarkably powerful diagnostic technique: it generates wide-ranging information for the non-invasive study of tissue anatomy and physiology. Complementary data is normally obtained in separate…

Image and Video Processing · Electrical Eng. & Systems 2019-01-24 Pedro A. Gómez , Miguel Molina-Romero , Guido Buonincontri , Marion I. Menzel , Bjoern H. Menze

This paper presents a method for virtual contrast enhancement in breast MRI, offering a promising non-invasive alternative to traditional contrast agent-based DCE-MRI acquisition. Using a conditional generative adversarial network, we…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Daniel M. Lang , Julia A. Schnabel , Oliver Diaz , Karim Lekadir

Multi-modal magnetic resonance imaging (MRI) is essential for providing complementary information about brain anatomy and pathology, leading to more accurate diagnoses. However, obtaining high-quality multi-modal MRI in a clinical setting…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Minjoo Lim , Bogyeong Kang , Tae-Eui Kam

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…

Medical Physics · Physics 2021-01-21 Erik Fredenberg , Magnus Hemmendorff , Bjorn Cederstrom , Magnus Aslund , Mats Danielsson

Cross-contrast image translation is an important task for completing missing contrasts in clinical diagnosis. However, most existing methods learn separate translator for each pair of contrasts, which is inefficient due to many possible…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Heran Yang , Jian Sun , Liwei Yang , Zongben Xu

While contrast-enhanced CT (CECT) is standard for assessing abdominal aortic aneurysms (AAA), the required iodinated contrast agents pose significant risks, including nephrotoxicity, patient allergies, and environmental harm. To reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yuxuan Ou , Ning Bi , Jiazhen Pan , Jiancheng Yang , Boliang Yu , Usama Zidan , Regent Lee , Vicente Grau
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