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Training vision-language models (VLMs) for medical report generation is often hindered by the scarcity of high-quality annotated data. This work evaluates the use of a weighted loss function to improve data efficiency. Compared to standard…

Computation and Language · Computer Science 2026-04-24 Alexander Weers , Daniel Rueckert , Martin J. Menten

Language models (LMs) represent an emerging paradigm within artificial intelligence, with applications throughout the medical enterprise. A comprehensive understanding of the clinical task and awareness of the variability in performance…

Machine Learning · Computer Science 2026-03-09 Victor Garcia , Mariia Sidulova , Aldo Badano

Machine Learning (ML) models have gained popularity in medical imaging analysis given their expert level performance in many medical domains. To enhance the trustworthiness, acceptance, and regulatory compliance of medical imaging models…

Human-Computer Interaction · Computer Science 2025-06-06 Mischa Dombrowski , Andrea Prenner , Bernhard Kainz

Natural Language Processing (NLP) is witnessing a remarkable breakthrough driven by the success of Large Language Models (LLMs). LLMs have gained significant attention across academia and industry for their versatile applications in text…

Computation and Language · Computer Science 2024-04-16 Taojun Hu , Xiao-Hua Zhou

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Deployment of machine learning (ML) algorithms in production for extended periods of time has uncovered new challenges such as monitoring and management of real-time prediction quality of a model in the absence of labels. However, such…

There is a vast literature on the determinants of subjective wellbeing. International organisations and statistical offices are now collecting such survey data at scale. However, standard regression models explain surprisingly little of the…

Machine learning (ML) empowers biomedical systems with the capability to optimize their performance through modeling of the available data extremely well, without using strong assumptions about the modeled system. Especially in nano-scale…

Most modern supervised statistical/machine learning (ML) methods are explicitly designed to solve prediction problems very well. Achieving this goal does not imply that these methods automatically deliver good estimators of causal…

Bias in applications of machine learning (ML) to healthcare is usually attributed to unrepresentative or incomplete data, or to underlying health disparities. This article identifies a more pervasive source of bias that affects the clinical…

Machine Learning · Computer Science 2023-08-07 Eran Tal

This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

Computation and Language · Computer Science 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

External validation is often recommended to ensure the generalizability of ML models. However, it neither guarantees generalizability nor equates to a model's clinical usefulness (the ultimate goal of any clinical decision-support tool).…

Machine Learning · Computer Science 2023-05-16 Alex Youssef , Michael Pencina , Anshul Thakur , Tingting Zhu , David Clifton , Nigam H. Shah

In this research we propose a new method for training predictive machine learning models for prescriptive applications. This approach, which we refer to as coupled validation, is based on tweaking the validation step in the standard…

Machine Learning · Computer Science 2021-10-25 Ebrahim Mortaz , Alexander Vinel

This paper considers the use of Machine Learning (ML) in medicine by focusing on the main problem that this computational approach has been aimed at solving or at least minimizing: uncertainty. To this aim, we point out how uncertainty is…

Machine Learning · Computer Science 2018-05-15 Federico Cabitza , Davide Ciucci , Raffaele Rasoini

Medical large language models (LLMs) research often makes bold claims, from encoding clinical knowledge to reasoning like a physician. These claims are usually backed by evaluation on competitive benchmarks; a tradition inherited from…

Computation and Language · Computer Science 2025-03-17 Ahmed Alaa , Thomas Hartvigsen , Niloufar Golchini , Shiladitya Dutta , Frances Dean , Inioluwa Deborah Raji , Travis Zack

Clinician scheduling remains a persistent challenge due to limited clinical resources and fluctuating demands. This complexity is especially acute in large academic anesthesiology departments as physicians balance responsibilities across…

Optimization and Control · Mathematics 2025-10-03 Anjali Jha , Wanqing Chen , Maxim Eckmann , Ian Stockwell , Jianwu Wang , Kai Sun

Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data…

Machine Learning · Computer Science 2021-03-25 Jussi Tohka , Mark van Gils

The rapid adoption of large language models (LLMs) in healthcare has been accompanied by scrutiny of their oversight. Existing monitoring approaches, inherited from traditional machine learning (ML), are task-based and founded on assumed…

Artificial Intelligence · Computer Science 2025-11-06 Katherine C. Kellogg , Bingyang Ye , Yifan Hu , Guergana K. Savova , Byron Wallace , Danielle S. Bitterman

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…