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Despite recent progress on semantic segmentation, there still exist huge challenges in medical ultra-resolution image segmentation. The methods based on multi-branch structure can make a good balance between computational burdens and…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Tong Wu , Yuan Xie , Yanyun Qu , Bicheng Dai , Shuxin Chen

Across many areas, from neural tracking to database entity resolution, manual assessment of clusters by human experts presents a bottleneck in rapid development of scalable and specialized clustering methods. To solve this problem we…

Machine Learning · Statistics 2020-03-20 Hanlin Zhu , Xue Li , Liuyang Sun , Fei He , Zhengtuo Zhao , Lan Luan , Ngoc Mai Tran , Chong Xie

DBSCAN, a well-known density-based clustering algorithm, has gained widespread popularity and usage due to its effectiveness in identifying clusters of arbitrary shapes and handling noisy data. However, it encounters challenges in producing…

Machine Learning · Computer Science 2025-05-09 Hao Peng , Xiang Huang , Shuo Sun , Ruitong Zhang , Philip S. Yu

With the ever-increasing use of web APIs in modern-day applications, it is becoming more important to test the system as a whole. In the last decade, tools and approaches have been proposed to automate the creation of system-level test…

Software Engineering · Computer Science 2021-09-15 Dimitri Stallenberg , Mitchell Olsthoorn , Annibale Panichella

Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Machine Learning · Computer Science 2025-09-29 Hanqun Cao , Xinyi Zhou , Zijun Gao , Chenyu Wang , Xin Gao , Zhi Zhang , Cesar de la Fuente-Nunez , Chunbin Gu , Ge Liu , Pheng-Ann Heng

Nodes localization in Wireless Sensor Networks (WSN) has arisen as a very challenging problem in the research community. Most of the applications for WSN are not useful without a priori known nodes positions. One solution to the problem is…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-27 Biljana Stojkoska , Danco Davcev , Andrea Kulakov

We investigate the adaptation and performance of modularity-based algorithms, designed in the scope of complex networks, to analyze the mesoscopic structure of correlation matrices. Using a multi-resolution analysis we are able to describe…

Data Analysis, Statistics and Probability · Physics 2011-03-31 Clara Granell , Sergio Gomez , Alex Arenas

Summary: With the rapid development of long-read sequencing technologies, the era of individual complete genomes is approaching. We have developed wgatools, a cross-platform, ultrafast toolkit that supports a range of whole genome alignment…

Genomics · Quantitative Biology 2025-04-01 Wenjie Wei , Songtao Gui , Jian Yang , Erik Garrison , Jianbing Yan , Hai-Jun Liu

The time complexity of data clustering has been viewed as fundamentally quadratic, slowing with the number of data items, as each item is compared for similarity to preceding items. Clustering of large data sets has been infeasible without…

Data Structures and Algorithms · Computer Science 2017-02-28 Jonathan A. Marshall , Lawrence C. Rafsky

Gaussian Graphical Models (GGMs) are widely used in high-dimensional data analysis to synthesize the interaction between variables. In many applications, such as genomics or image analysis, graphical models rely on sparsity and clustering…

Machine Learning · Statistics 2026-03-25 Do Edmond Sanou , Christophe Ambroise , Geneviève Robin

Hierarchical clustering is a fundamental task often used to discover meaningful structures in data, such as phylogenetic trees, taxonomies of concepts, subtypes of cancer, and cascades of particle decays in particle physics. Typically…

Data Structures and Algorithms · Computer Science 2020-10-23 Craig S. Greenberg , Sebastian Macaluso , Nicholas Monath , Ji-Ah Lee , Patrick Flaherty , Kyle Cranmer , Andrew McGregor , Andrew McCallum

There has been a surge in the number of large and flat data sets - data sets containing a large number of features and a relatively small number of observations - due to the growing ability to collect and store information in medical…

Machine Learning · Statistics 2017-07-05 Hongyang Zhang , Ruben H. Zamar

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

Multidimensional scaling is an important dimension reduction tool in statistics and machine learning. Yet few theoretical results characterizing its statistical performance exist, not to mention any in high dimensions. By considering a…

Methodology · Statistics 2022-03-30 Xiucai Ding , Qiang Sun

We proposed a probabilistic algorithm to solve the Multiple Sequence Alignment problem. The algorithm is a Simulated Annealing (SA) that exploits the representation of the Multiple Alignment between $D$ sequences as a directed polymer in…

Genomics · Quantitative Biology 2016-08-16 M. Hernández-Guía , R. Mulet , S. Rodríguez-Pérez

In sequence to sequence learning, the self-attention mechanism proves to be highly effective, and achieves significant improvements in many tasks. However, the self-attention mechanism is not without its own flaws. Although self-attention…

Computation and Language · Computer Science 2019-11-22 Guangxiang Zhao , Xu Sun , Jingjing Xu , Zhiyuan Zhang , Liangchen Luo

Multiple sequences alignment (MSA) is a traditional and challenging task for time-series analyses. The MSA problem is formulated as a discrete optimization problem and is typically solved by dynamic programming. However, the computational…

Machine Learning · Computer Science 2020-06-30 Keisuke Kawano , Takuro Kutsuna , Satoshi Koide

In this work we present a clustering technique called \textit{multi-level conformal clustering (MLCC)}. The technique is hierarchical in nature because it can be performed at multiple significance levels which yields greater insight into…

Machine Learning · Statistics 2020-06-25 Ilia Nouretdinov , James Gammerman , Matteo Fontana , Daljit Rehal

Self-supervised temporal sequence alignment can provide rich and effective representations for a wide range of applications. However, existing methods for achieving optimal performance are mostly limited to aligning sequences of the same…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Taein Kwon , Zador Pataki , Mahdi Rad , Marc Pollefeys

We present a robust multiple manifolds structure learning (RMMSL) scheme to robustly estimate data structures under the multiple low intrinsic dimensional manifolds assumption. In the local learning stage, RMMSL efficiently estimates local…

Machine Learning · Computer Science 2012-06-22 Dian Gong , Xuemei Zhao , Gerard Medioni