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Cancer diagnosis has greatly benefited from the integration of whole-slide images (WSIs) with multiple instance learning (MIL), enabling high-resolution analysis of tissue morphology. Graph-based MIL (GNN-MIL) approaches have emerged as…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Jongwoo Kim , Bryan Wong , Huazhu Fu , Willmer Rafell Quiñones , Youngsin Ko , Mun Yong Yi

Colonoscopy is crucial for identifying adenomatous polyps and preventing colorectal cancer. However, developing robust models for polyp detection is challenging by the limited size and accessibility of existing colonoscopy datasets. While…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Yifan Xie , Jingge Wang , Tao Feng , Fei Ma , Yang Li

Inflammatory bowel disease (IBD), in particular ulcerative colitis (UC), is graded by endoscopists and this assessment is the basis for risk stratification and therapy monitoring. Presently, endoscopic characterisation is largely operator…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ziang Xu , Sharib Ali , Soumya Gupta , Simon Leedham , James E East , Jens Rittscher

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Colorectal cancer is one of the most common cancers in the world. While colonoscopy is an effective screening technique, navigating an endoscope through the colon to detect polyps is challenging. A 3D map of the observed surfaces could…

Colorectal cancer is one of the deadliest cancers today, but it can be prevented through early detection of malignant polyps in the colon, primarily via colonoscopies. While this method has saved many lives, human error remains a…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Jose Angel Nuñez , Fabian Vazquez , Diego Adame , Xiaoyan Fu , Pengfei Gu , Bin Fu

Accurate assessment of bowel cleanliness is essential for effective colonoscopy procedures. The Boston Bowel Preparation Scale (BBPS) offers a standardized scoring system but suffers from subjectivity and inter-observer variability when…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Yujia Fu , Zhiyu Dong , Tianwen Qian , Chenye Zheng , Danian Ji , Linhai Zhuo

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Differentiation of colorectal polyps is an important clinical examination. A computer-aided diagnosis system is required to assist accurate diagnosis from colonoscopy images. Most previous studies at-tempt to develop models for polyp…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Qin Wang , Hui Che , Weizhen Ding , Li Xiang , Guanbin Li , Zhen Li , Shuguang Cui

Precise and real-time detection of gastrointestinal polyps during endoscopic procedures is crucial for early diagnosis and prevention of colorectal cancer. This work presents EndoSight AI, a deep learning architecture developed and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Daniel Cavadia

Multiple Instance Learning (MIL) has demonstrated promise in Whole Slide Image (WSI) classification. However, a major challenge persists due to the high computational cost associated with processing these gigapixel images. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Medical Image Segmentation (MIS) plays a crucial role in medical therapy planning and robot navigation. Prototype learning methods in MIS focus on generating segmentation masks through pixel-to-prototype comparison. However, current…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Zhe Wang , Chang Yao

Ulcerative colitis (UC) classification, which is an important task for endoscopic diagnosis, involves two main difficulties. First, endoscopic images with the annotation about UC (positive or negative) are usually limited. Second, they show…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Shota Harada , Ryoma Bise , Hideaki Hayashi , Kiyohito Tanaka , Seiichi Uchida

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Biomedical image segmentation is a very important part in disease diagnosis. The term "colonic polyps" refers to polypoid lesions that occur on the surface of the colonic mucosa within the intestinal lumen. In clinical practice, early…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Chen Peng , Zhiqin Qian , Kunyu Wang , Qi Luo , Zhuming Bi , Wenjun Zhang

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A. Fallowfield , Hideki Ueno , Hitoshi Tsuda , David J. Harrison , Hakan Bilen , Timothy J. Kendall

Multi-label classification (MLC) of medical images aims to identify multiple diseases and holds significant clinical potential. A critical step is to learn class-specific features for accurate diagnosis and improved interpretability…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Xiaoxiao Cui , Yiran Li , Kai He , Shanzhi Jiang , Mengli Xue , Wentao Li , Junhong Leng , Zhi Liu , Lizhen Cui , Shuo Li