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Multiple instance learning (MIL) is a powerful approach to classify whole slide images (WSIs) for diagnostic pathology. A fundamental challenge of MIL on WSI classification is to discover the \textit{critical instances} that trigger the bag…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Zhikang Wang , Yue Bi , Tong Pan , Xiaoyu Wang , Chris Bain , Richard Bassed , Seiya Imoto , Jianhua Yao , Jiangning Song

Automatic detection of polyps is challenging because different polyps vary greatly, while the changes between polyps and their analogues are small. The state-of-the-art methods are based on convolutional neural networks (CNNs). However,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-26 Jianwei Xu , Ran Zhao , Yizhou Yu , Qingwei Zhang , Xianzhang Bian , Jun Wang , Zhizheng Ge , Dahong Qian

Segmenting polyps in colonoscopy images is essential for the early identification and diagnosis of colorectal cancer, a significant cause of worldwide cancer deaths. Prior deep learning based models such as Attention based variation, UNet…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Al Mohimanul Islam , Sadia Shakiba Bhuiyan , Mysun Mashira , Md. Rayhan Ahmed , Salekul Islam , Swakkhar Shatabda

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

Colonoscopic Polyp Re-Identification aims to match the same polyp from a large gallery with images from different views taken using different cameras and plays an important role in the prevention and treatment of colorectal cancer. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Suncheng Xiang , Chengfeng Zhou , Zhengjie Zhang , Shilun Cai , Dahong Qian

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Histopathological characterization of colorectal polyps is an important principle for determining the risk of colorectal cancer and future rates of surveillance for patients. This characterization is time-intensive, requires years of…

Computer Vision and Pattern Recognition · Computer Science 2017-04-14 Bruno Korbar , Andrea M. Olofson , Allen P. Miraflor , Katherine M. Nicka , Matthew A. Suriawinata , Lorenzo Torresani , Arief A. Suriawinata , Saeed Hassanpour

Automatic detection of colonic polyps is still an unsolved problem due to the large variation of polyps in terms of shape, texture, size, and color, and the existence of various polyp-like mimics during colonoscopy. In this study, we apply…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Younghak Shin , Hemin Ali Qadir , Lars Aabakken , Jacob Bergsland , Ilangko Balasingham

Validation metrics are a key prerequisite for the reliable tracking of scientific progress and for deciding on the potential clinical translation of methods. While recent initiatives aim to develop comprehensive theoretical frameworks for…

The dynamic environment of laboratories and clinics, with streams of data arriving on a daily basis, requires regular updates of trained machine learning models for consistent performance. Continual learning is supposed to help train models…

Machine Learning · Computer Science 2025-08-12 Zahra Ebrahimi , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Colonic polyps are well-recognized precursors to colorectal cancer (CRC), typically detected during colonoscopy. However, the variability in appearance, location, and size of these polyps complicates their detection and removal, leading to…

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

We study a multiclass multiple instance learning (MIL) problem where the labels only suggest whether any instance of a class exists or does not exist in a training sample or example. No further information, e.g., the number of instances of…

Machine Learning · Statistics 2019-03-15 Xi-Lin Li

In this paper, we propose and analyse a system that can automatically detect, localise and classify polyps from colonoscopy videos. The detection of frames with polyps is formulated as a few-shot anomaly classification problem, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Yu Tian , Leonardo Zorron Cheng Tao Pu , Yuyuan Liu , Gabriel Maicas , Johan W. Verjans , Alastair D. Burt , Seon Ho Shin , Rajvinder Singh , Gustavo Carneiro

Current polyp detection methods from colonoscopy videos use exclusively normal (i.e., healthy) training images, which i) ignore the importance of temporal information in consecutive video frames, and ii) lack knowledge about the polyps.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Yu Tian , Guansong Pang , Fengbei Liu , Yuyuan Liu , Chong Wang , Yuanhong Chen , Johan W Verjans , Gustavo Carneiro

Wireless Capsule Endoscopy (WCE) is a relatively new technology to record the entire GI trace, in vivo. The large amounts of frames captured during an examination cause difficulties for physicians to review all these frames. The need for…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Omid Haji Maghsoudi

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Multi-instance learning (MIL) is a form of weakly supervised learning where a single class label is assigned to a bag of instances while the instance-level labels are not available. Training classifiers to accurately determine the bag label…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Bin Li , Kevin W. Eliceiri

Deep learning models have been proposed for automatic polyp detection and precise segmentation of polyps during colonoscopy procedures. Although these state-of-the-art models achieve high performance, they often require a large number of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Tugberk Erol , Tuba Caglikantar , Duygu Sarikaya