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Related papers: Biological Sequence Clustering: A Survey

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We study the problem of clustering sequences of unlabeled point sets taken from a common metric space. Such scenarios arise naturally in applications where a system or process is observed in distinct time intervals, such as biological…

Data Structures and Algorithms · Computer Science 2017-10-17 Tamal K. Dey , Alfred Rossi , Anastasios Sidiropoulos

The paper surveys the evolution of main algorithmic techniques to compare and search biological sequences. We highlight key algorithmic ideas emerged in response to several interconnected factors: shifts of biological analytical paradigm,…

Genomics · Quantitative Biology 2018-11-15 Gregory Kucherov

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Clustering aims to group unlabeled objects based on similarity inherent among them into clusters. It is important for many tasks such as anomaly detection, database sharding, record linkage, and others. Some clustering methods are taken as…

Databases · Computer Science 2024-12-02 Binbin Gu , Saeed Kargar , Faisal Nawab

Analyses of targeted genomic sequencing data from next-generation-sequencing (NGS) technologies typically involves mapping reads to a reference sequence or clustering reads. For a number of species a reference genome is not available so the…

Genomics · Quantitative Biology 2016-02-16 Raunaq Malhotra , Daniel Elleder , Le Bao , David R Hunter , Raj Acharya , Mary Poss

Clustering is a common technique for statistical data analysis, which is used in many fields, including machine learning, data mining, pattern recognition, image analysis and bioinformatics. Clustering is the process of grouping similar…

Data Structures and Algorithms · Computer Science 2012-05-08 T. Soni Madhulatha

Clustering is a well-known unsupervised machine learning approach capable of automatically grouping discrete sets of instances with similar characteristics. Constrained clustering is a semi-supervised extension to this process that can be…

Machine Learning · Computer Science 2023-03-02 Germán González-Almagro , Daniel Peralta , Eli De Poorter , José-Ramón Cano , Salvador García

Clustering algorithms are widely utilized for many modern data science applications. This motivates the need to make outputs of clustering algorithms fair. Traditionally, new fair algorithmic variants to clustering algorithms are developed…

Machine Learning · Computer Science 2021-10-26 Anshuman Chhabra , Adish Singla , Prasant Mohapatra

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Cell clustering is crucial for uncovering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq) data by identifying cell types and marker genes. Despite its importance, benchmarks for scRNA-seq clustering methods remain…

Genomics · Quantitative Biology 2025-12-03 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Jiajia Wang , Ran Zhang , Pengfei Wang , Yuanchun Zhou

Density-based cluster mining is known to serve a broad range of applications ranging from stock trade analysis to moving object monitoring. Although methods for efficient extraction of density-based clusters have been studied in the…

Databases · Computer Science 2011-11-01 Di Yang , Elke A. Rundensteiner , Matthew O. Ward

In recent years, much of the research on clustering algorithms has primarily focused on enhancing their accuracy and efficiency, frequently at the expense of interpretability. However, as these methods are increasingly being applied in…

Machine Learning · Computer Science 2026-01-21 Lianyu Hu , Mudi Jiang , Junjie Dong , Xinying Liu , Zengyou He

Graph clustering, which aims to divide nodes in the graph into several distinct clusters, is a fundamental yet challenging task. Benefiting from the powerful representation capability of deep learning, deep graph clustering methods have…

Machine Learning · Computer Science 2023-09-13 Yue Liu , Jun Xia , Sihang Zhou , Xihong Yang , Ke Liang , Chenchen Fan , Yan Zhuang , Stan Z. Li , Xinwang Liu , Kunlun He

Clustering techniques are very attractive for extracting and identifying patterns in datasets. However, their application to very large spatial datasets presents numerous challenges such as high-dimensionality data, heterogeneity, and high…

Databases · Computer Science 2018-02-27 Malika Bendechache , Nhien-An Le-Khac , M-Tahar Kechadi

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

In recent years, the advances in single-cell RNA-seq techniques have enabled us to perform large-scale transcriptomic profiling at single-cell resolution in a high-throughput manner. Unsupervised learning such as data clustering has become…

Genomics · Quantitative Biology 2020-01-07 Shixiong Zhang , Xiangtao Li , Qiuzhen Lin , Ka-Chun Wong

A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimension ($N_{_{D}}>3$). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clustering…

Data Analysis, Statistics and Probability · Physics 2017-10-16 Kevin McIlhany , Stephen Wiggins

We present a technique for clustering categorical data by generating many dissimilarity matrices and averaging over them. We begin by demonstrating our technique on low dimensional categorical data and comparing it to several other…

Machine Learning · Statistics 2017-09-20 Saeid Amiri , Bertrand Clarke , Jennifer Clarke

Data-based classification is fundamental to most branches of science. While recent years have brought enormous progress in various areas of statistical computing and clustering, some general challenges in clustering remain: model selection,…

Artificial Intelligence · Computer Science 2007-06-13 Jens Oehlschlägel