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Unsupervised Domain Adaptation (UDA) aims to enhance the generalization of the learned model to other domains. The domain-invariant knowledge is transferred from the model trained on labeled source domain, e.g., video game, to unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Mu Chen , Zhedong Zheng , Yi Yang , Tat-Seng Chua

Significant differences in protein structures hinder the generalization of existing drug-target interaction (DTI) models, which often rely heavily on pre-learned binding principles or detailed annotations. In contrast, BioBridge designs an…

Machine Learning · Computer Science 2025-03-28 Xiaoqing Lian , Jie Zhu , Tianxu Lv , Shiyun Nie , Hang Fan , Guosheng Wu , Yunjun Ge , Lihua Li , Xiangxiang Zeng , Xiang Pan

Trajectory data has become a key resource for automated map in-ference due to its low cost, broad coverage, and continuous availability. However, uneven trajectory density often leads to frag-mented roads in sparse areas and redundant…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Yudong Shen , Wenyu Wu , Jiali Mao , Yixiao Tong , Guoping Liu , Chaoya Wang

Unsupervised domain adaptation (UDA) is a pivotal form in machine learning to extend the in-domain model to the distinctive target domains where the data distributions differ. Most prior works focus on capturing the inter-domain…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Zhiqing Xiao , Haobo Wang , Ying Jin , Lei Feng , Gang Chen , Fei Huang , Junbo Zhao

We propose SparseContrast, a new framework that merges dynamic sparse attention with contrastive learning for medical imaging, with a focus on chest X-ray disease detection in low-data settings. Traditional contrastive learning methods rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Paarth Prasad , Ruchika Malhotra

Visual attention has been extensively studied for learning fine-grained features in both facial expression recognition (FER) and Action Unit (AU) detection. A broad range of previous research has explored how to use attention modules to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Xiaotian Li , Zhihua Li , Huiyuan Yang , Geran Zhao , Lijun Yin

The characterization of drug-protein interactions is crucial in the high-throughput screening for drug discovery. The deep learning-based approaches have attracted attention because they can predict drug-protein interactions without…

Machine Learning · Computer Science 2020-12-22 QHwan Kim , Joon-Hyuk Ko , Sunghoon Kim , Nojun Park , Wonho Jhe

In-silico prediction of repurposable drugs is an effective drug discovery strategy that supplements de-nevo drug discovery from scratch. Reduced development time, less cost and absence of severe side effects are significant advantages of…

Machine Learning · Computer Science 2021-02-23 Sk Mazharul Islam , Sk Md Mosaddek Hossain , Sumanta Ray

The quadratic cost of attention limits the scalability of long-context LLMs, especially under limited hardware memory budgets. While attention is often sparse, existing static sparse methods cannot adapt to task- or input-dependent…

Computation and Language · Computer Science 2026-05-29 Siheng Xiong , Joe Zou , Faramarz Fekri , Yae Jee Cho

Dysarthric speech detection (DSD) systems aim to detect characteristics of the neuromotor disorder from speech. Such systems are particularly susceptible to domain mismatch where the training and testing data come from the source and target…

Audio and Speech Processing · Electrical Eng. & Systems 2021-07-26 Disong Wang , Liqun Deng , Yu Ting Yeung , Xiao Chen , Xunying Liu , Helen Meng

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Inspired by the human cognitive system, attention is a mechanism that imitates the human cognitive awareness about specific information, amplifying critical details to focus more on the essential aspects of data. Deep learning has employed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Mohammed Hassanin , Saeed Anwar , Ibrahim Radwan , Fahad S Khan , Ajmal Mian

The remarkable success of contrastive-learning-based multimodal models has been greatly driven by training on ever-larger datasets with expensive compute consumption. Sample selection as an alternative efficient paradigm plays an important…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zihua Zhao , Feng Hong , Mengxi Chen , Pengyi Chen , Benyuan Liu , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Deep learning has shown remarkable performance in medical image segmentation. However, despite its promise, deep learning has many challenges in practice due to its inability to effectively transition to unseen domains, caused by the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Dewei Hu , Hao Li , Han Liu , Jiacheng Wang , Xing Yao , Daiwei Lu , Ipek Oguz

Effective long-term predictions have been increasingly demanded in urban-wise data mining systems. Many practical applications, such as accident prevention and resource pre-allocation, require an extended period for preparation. However,…

Information Retrieval · Computer Science 2020-06-17 Haoxing Lin , Rufan Bai , Weijia Jia , Xinyu Yang , Yongjian You

Vision-language models (VLMs), e.g., CLIP, have shown remarkable potential in zero-shot image classification. However, adapting these models to new domains remains challenging, especially in unsupervised settings where labeled data is…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Eman Ali , Sathira Silva , Muhammad Haris Khan

Speaker recognition models face challenges in multi-lingual settings due to the entanglement of linguistic information within speaker embeddings. The overlap between vocal traits such as accent, vocal anatomy, and a language's phonetic…

Sound · Computer Science 2025-06-04 Aditya Srinivas Menon , Raj Prakash Gohil , Kumud Tripathi , Pankaj Wasnik

Semantic segmentation of histopathology images under class imbalance is typically addressed through frequency-based loss reweighting, which implicitly assumes that rare classes are difficult. However, true difficulty also arises from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Lakmali Nadeesha Kumari , Sen-Ching Samson Cheung

Although traffic sign detection has been studied for years and great progress has been made with the rise of deep learning technique, there are still many problems remaining to be addressed. For complicated real-world traffic scenes, there…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Yuan Yuan , Zhitong Xiong , Qi Wang

Drug discovery projects entail cycles of design, synthesis, and testing that yield a series of chemically related small molecules whose properties, such as binding affinity to a given target protein, are progressively tailored to a…

Machine Learning · Computer Science 2020-02-10 Paul Maragakis , Hunter Nisonoff , Brian Cole , David E. Shaw
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