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We propose a prognostic stratum matching framework that addresses the deficiencies of Randomized trial data subgroup analysis and transforms ObservAtional Data to be used as if they were randomized, thus paving the road for precision…

Applications · Statistics 2023-11-06 Dimitris Bertsimas , Angelos G. Koulouras , Georgios Antonios Margonis

Personalized medicine has gained much popularity recently as a way of providing better healthcare by tailoring treatments to suit individuals. Our research, motivated by the UK INTERVAL blood donation trial, focuses on estimating the…

Methodology · Statistics 2023-02-24 Yuejia Xu , Angela M. Wood , David J. Roberts , Brian D. M. Tom

The rates of respiratory prescriptions vary by GP surgery across Scotland, suggesting there are sizeable health inequalities in respiratory ill health across the country. The aim of this paper is to estimate the magnitude, spatial pattern…

Applications · Statistics 2017-04-24 Duncan Lee

This work proposes a two-step method to enhance disease risk estimation in small areas by integrating spatiotemporal cluster detection within a Bayesian hierarchical spatiotemporal model. First, we introduce an efficient…

Methodology · Statistics 2026-04-14 G. Santafé , A. Adin , M. D. Ugarte

Indirect standardization is widely used in disease mapping to control for confounding, but relies on restrictive assumptions that may bias estimates if violated. Using data on suicide-related emergency calls, this study highlights such…

Methodology · Statistics 2025-07-17 J. Martín-Pozuelo , A. López-Quílez , X. Barber , M. Marco

Regression discontinuity (RD) is a widely used quasi-experimental design for causal inference. In the standard RD, the assignment to treatment is determined by a continuous pretreatment variable (i.e., running variable) falling above or…

Methodology · Statistics 2020-06-23 Fan Li , Andrea Mercatanti , Taneli Makinen , Andrea Silvestrini

There is a growing need for flexible general frameworks that integrate individual-level data with external summary information for improved statistical inference. External information relevant for a risk prediction model may come in…

Methodology · Statistics 2023-04-11 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Policy evaluation in empirical microeconomics has been focusing on estimating the average treatment effect and more recently the heterogeneous treatment effects, often relying on the unconfoundedness assumption. We propose a method based on…

Econometrics · Economics 2023-06-06 Wei Tian

Data-driven epidemic simulation helps better policymaking. Compared with macro-scale simulations driven by statistical data, individual-level GPS data can afford finer and spatialized results. However, the big GPS data, usually collected…

Computers and Society · Computer Science 2022-03-01 Guixu Lin , Defan Feng , Peiran Li , Yicheng Zhao , Haoran Zhang , Xuan Song

In statistics, forecast uncertainty is often quantified using a specified statistical model, though such approaches may be vulnerable to model misspecification, selection bias, and limited finite-sample validity. While bootstrapping can…

Methodology · Statistics 2026-03-12 Han Lin Shang

Ordinal outcomes are common in clinical settings where they often represent increasing levels of disease progression or different levels of functional impairment. Such outcomes can characterize differences in meaningful patient health…

Existing inferential methods for small area data involve a trade-off between maintaining area-level frequentist coverage rates and improving inferential precision via the incorporation of indirect information. In this article, we propose a…

Methodology · Statistics 2022-04-19 Elizabeth Bersson , Peter D. Hoff

We study a simple model of epidemics where an infected node transmits the infection to its neighbors independently with probability $p$. This is also known as the independent cascade or Susceptible-Infected-Recovered (SIR) model with fixed…

Data Structures and Algorithms · Computer Science 2021-10-19 Yeganeh Alimohammadi , Christian Borgs , Amin Saberi

Medical investigations focusing on patient survival often generate not only a failure time for each patient but also a sequence of measurements on patient health at annual or semi-annual check-ups while the patient remains alive. Such a…

Methodology · Statistics 2016-01-18 Peter McCullagh , Walter Dempsey

The dramatic growth of big datasets presents a new challenge to data storage and analysis. Data reduction, or subsampling, that extracts useful information from datasets is a crucial step in big data analysis. We propose an orthogonal…

Methodology · Statistics 2021-06-01 Lin Wang , Jake Elmstedt , Weng Kee Wong , Hongquan Xu

Quantifying uncertainty in clinical predictions is critical for high-stakes diagnosis tasks. Conformal prediction offers a principled approach by providing prediction sets with theoretical coverage guarantees. However, in practice, patient…

Machine Learning · Computer Science 2026-05-01 Arjun Chatterjee , Sayeed Sajjad Razin , John Wu , Siddhartha Laghuvarapu , Jathurshan Pradeepkumar , Jimeng Sun

Estimation of the long-term health effects of air pollution is a challenging task, especially when modelling small-area disease incidence data in an ecological study design. The challenge comes from the unobserved underlying spatial…

Methodology · Statistics 2013-05-24 Duncan Lee , Alastair Rushworth , Sujit K. Sahu

This study proposes an accurate method to estimate human body orientation using a millimeter-wave radar system. Body displacement is measured from the phase of the radar echo, which is analyzed to obtain features associated with the…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Wenxu Sun , Shunsuke Iwata , Yuji Tanaka , Takuya Sakamoto

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Survival regression is widely used to model time-to-events data, to explore how covariates may influence the occurrence of events. Modern datasets often encompass a vast number of covariates across many subjects, with only a subset of the…

Methodology · Statistics 2024-09-18 Abhishek Mandal , Abhisek Chakraborty
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