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Depression is one of the most common mental illness problems, and the symptoms shown by patients are not consistent, making it difficult to diagnose in the process of clinical practice and pathological research. Although researchers hope…

Computers and Society · Computer Science 2024-10-08 Xiaohang Xu , Hao Peng , Lichao Sun , Md Zakirul Alam Bhuiyan , Lianzhong Liu , Lifang He

We study Federated Causal Inference, an approach to estimate treatment effects from decentralized data across centers. We compare three classes of Average Treatment Effect (ATE) estimators derived from the Plug-in G-Formula, ranging from…

Machine Learning · Statistics 2025-03-26 Rémi Khellaf , Aurélien Bellet , Julie Josse

Connectivity matrices derived from diffusion MRI (dMRI) provide an interpretable and generalizable way of understanding the human brain connectome. However, dMRI suffers from inter-site and between-scanner variation, which impedes analysis…

The emerging paradigm of federated learning (FL) strives to enable collaborative training of deep models on the network edge without centrally aggregating raw data and hence improving data privacy. In most cases, the assumption of…

Machine Learning · Computer Science 2021-05-12 Xiaoxiao Li , Meirui Jiang , Xiaofei Zhang , Michael Kamp , Qi Dou

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Federated Learning (FL) enables collaborative model training across decentralized edge devices while preserving data privacy. However, statistical heterogeneity among clients, often manifested as non-IID label distributions, poses…

Machine Learning · Computer Science 2026-01-06 Sameer Rahil , Zain Abdullah Ahmad , Talha Asif

Federated techniques such as federated learning and federated analysis have emerged as a powerful paradigm for enabling multi-center research on sensitive clinical data while preserving patient privacy. In this study, we introduce a…

Machine Learning · Computer Science 2026-05-12 Evelyn Trautmann , Joël Federer-Gsponer , Markus C. Elze , José-Tomás Prieto

Although data-driven methods usually have noticeable performance on disease diagnosis and treatment, they are suspected of leakage of privacy due to collecting data for model training. Recently, federated learning provides a secure and…

Artificial Intelligence · Computer Science 2023-06-27 Yawei Zhao , Qinghe Liu , Xinwang Liu , Kunlun He

The ability to combine data across scanners and studies is vital for neuroimaging, to increase both statistical power and the representation of biological variability. However, combining datasets across sites leads to two challenges: first,…

Machine Learning · Computer Science 2022-06-01 Nicola K Dinsdale , Mark Jenkinson , Ana IL Namburete

In mobile and IoT systems, Federated Learning (FL) is increasingly important for effectively using data while maintaining user privacy. One key challenge in FL is managing statistical heterogeneity, such as non-i.i.d. data, arising from…

Machine Learning · Computer Science 2024-05-17 Kunda Yan , Sen Cui , Abudukelimu Wuerkaixi , Jingfeng Zhang , Bo Han , Gang Niu , Masashi Sugiyama , Changshui Zhang

Functional data is a powerful tool for capturing and analyzing complex patterns and relationships in a variety of fields, allowing for more precise modeling, visualization, and decision-making. For example, in healthcare, functional data…

Methodology · Statistics 2023-04-26 Xiyuan Gao , Jiayi Wang , Guanyu Hu , Jianguo Sun

We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

Machine Learning · Computer Science 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

Many major works in social science employ matching to make causal conclusions, but different matches on the same data may produce different treatment effect estimates, even when they achieve similar balance or minimize the same loss…

Applications · Statistics 2023-03-23 Marco Morucci , Cynthia Rudin

A major data pre-processing step for large, multi-site studies is to handle site effects by harmonizing data, generating a dataset that enables more powerful analyses and more robust algorithms. There is a wide variety of data harmonization…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Tom Osika , Ebrahim Ebrahim , Martin Styner , Marc Niethammer , Thomas Sawyer , Andinet Enquobahrie

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

Machine Learning · Statistics 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Federated learning has faced performance and network communication challenges, especially in the environments where the data is not independent and identically distributed (IID) across the clients. To address the former challenge, we…

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Cross-client data heterogeneity in federated learning induces biases that impede unbiased consensus condensation and the complementary fusion of generalization- and personalization-oriented knowledge. While existing approaches mitigate…

Machine Learning · Computer Science 2025-08-26 Ming Yang , Dongrun Li , Xin Wang , Xiaoyang Yu , Xiaoming Wu , Shibo He

In the medical field, multi-center collaborations are often sought to yield more generalizable findings by leveraging the heterogeneity of patient and clinical data. However, recent privacy regulations hinder the possibility to share data,…

Integrating Electronic Health Records (EHR) and the application of machine learning present opportunities for enhancing the accuracy and accessibility of data-driven diabetes prediction. In particular, developing data-driven machine…

Computational Engineering, Finance, and Science · Computer Science 2024-08-23 Guojun Tang , Jason E. Black , Tyler S. Williamson , Steve H. Drew