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Extracting social determinants of health (SDoH) from unstructured medical notes depends heavily on labor-intensive annotations, which are typically task-specific, hampering reusability and limiting sharing. In this study we introduced…

Computation and Language · Computer Science 2024-07-25 Bernardo Consoli , Xizhi Wu , Song Wang , Xinyu Zhao , Yanshan Wang , Justin Rousseau , Tom Hartvigsen , Li Shen , Huanmei Wu , Yifan Peng , Qi Long , Tianlong Chen , Ying Ding

Diabetes is a chronic disease with a significant global health burden, requiring multi-stakeholder collaboration for optimal management. Large language models (LLMs) have shown promise in various healthcare scenarios, but their…

Computation and Language · Computer Science 2025-03-14 Lai Wei , Zhen Ying , Muyang He , Yutong Chen , Qian Yang , Yanzhe Hong , Jiaping Lu , Kaipeng Zheng , Shaoting Zhang , Xiaoying Li , Weiran Huang , Ying Chen

Substance use disorder (SUD) poses a major concern due to its detrimental effects on health and society. SUD identification and treatment depend on a variety of factors such as severity, co-determinants (e.g., withdrawal symptoms), and…

Computation and Language · Computer Science 2024-03-20 Maria Mahbub , Gregory M. Dams , Sudarshan Srinivasan , Caitlin Rizy , Ioana Danciu , Jodie Trafton , Kathryn Knight

While Machine Learning (ML) and Deep Learning (DL) models have been widely used for diabetes prediction, the use of Large Language Models (LLMs) for structured numerical data is still not well explored. In this study, we test the…

Computation and Language · Computer Science 2025-06-19 Shadman Sakib , Oishy Fatema Akhand , Ajwad Abrar

Social determinants of health (SDOH) -- the conditions in which people live, grow, and age -- play a crucial role in a person's health and well-being. There is a large, compelling body of evidence in population health studies showing that a…

Machine Learning · Computer Science 2023-08-15 Ming Ying Yang , Gloria Hyunjung Kwak , Tom Pollard , Leo Anthony Celi , Marzyeh Ghassemi

We present DM-Bench, the first benchmark designed to evaluate large language model (LLM) performance across real-world decision-making tasks faced by individuals managing diabetes in their daily lives. Unlike prior health benchmarks that…

Machine Learning · Computer Science 2025-10-06 Maria Ana Cardei , Josephine Lamp , Mark Derdzinski , Karan Bhatia

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

Objective: The 2022 n2c2 NLP Challenge posed identification of social determinants of health (SDOH) in clinical narratives. We present three systems that we developed for the Challenge and discuss the distinctive task formulation used in…

Computation and Language · Computer Science 2023-01-30 Manabu Torii , Ian M. Finn , Son Doan , Paul Wang , Elly W. Yang , Daniel S. Zisook

Patient life circumstances, including social determinants of health (SDOH), shape both health outcomes and care access, contributing to persistent disparities across gender, race, and socioeconomic status. Liver transplantation exemplifies…

Objective: The n2c2/UW SDOH Challenge explores the extraction of social determinant of health (SDOH) information from clinical notes. The objectives include the advancement of natural language processing (NLP) information extraction…

Computation and Language · Computer Science 2023-02-15 Kevin Lybarger , Meliha Yetisgen , Özlem Uzuner

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Heart Failure (HF) affects millions of Americans and leads to high readmission rates, posing significant healthcare challenges. While Social Determinants of Health (SDOH) such as socioeconomic status and housing stability play critical…

Machine Learning · Computer Science 2025-09-29 Mingchen Shao , Youjeong Kang , Xiao Hu , Hyunjung Gloria Kwak , Carl Yang , Jiaying Lu

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

The ability to predict drug overdose risk from a patient's medical records is crucial for timely intervention and prevention. Traditional machine learning models have shown promise in analyzing longitudinal medical records for this task.…

Artificial Intelligence · Computer Science 2025-04-17 Md Sultan Al Nahian , Chris Delcher , Daniel Harris , Peter Akpunonu , Ramakanth Kavuluru

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

Machine Learning · Computer Science 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec

Background: Understanding social determinants of health (SDoH) factors contributing to suicide incidents is crucial for early intervention and prevention. However, data-driven approaches to this goal face challenges such as long-tailed…

Computation and Language · Computer Science 2025-08-08 Song Wang , Yishu Wei , Haotian Ma , Max Lovitt , Kelly Deng , Yuan Meng , Zihan Xu , Jingze Zhang , Yunyu Xiao , Ying Ding , Xuhai Xu , Joydeep Ghosh , Yifan Peng

Social and behavioral determinants of health (SBDoH) have important roles in shaping people's health. In clinical research studies, especially comparative effectiveness studies, failure to adjust for SBDoH factors will potentially cause…

Computation and Language · Computer Science 2021-08-12 Zehao Yu , Xi Yang , Chong Dang , Songzi Wu , Prakash Adekkanattu , Jyotishman Pathak , Thomas J. George , William R. Hogan , Yi Guo , Jiang Bian , Yonghui Wu