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Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Arbel Hizmi , Artemii Bakulin , Shai Bagon , Nir Yosef

The recent trend in multiple object tracking (MOT) is heading towards leveraging deep learning to boost the tracking performance. In this paper, we propose a novel solution named TransSTAM, which leverages Transformer to effectively model…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Peng Dai , Yiqiang Feng , Renliang Weng , Changshui Zhang

Hyperspectral image (HSI) denoising is a crucial preprocessing procedure for the subsequent HSI applications. Unfortunately, though witnessing the development of deep learning in HSI denoising area, existing convolution-based methods face…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Miaoyu Li , Ying Fu , Yulun Zhang

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

High-resolution spatial transcriptomics (HR-ST) technologies offer unprecedented insights into tissue architecture but lack standardized frameworks for histological annotation. We present ST2HE, a cross-platform generative framework that…

Quantitative Methods · Quantitative Biology 2025-10-16 Zhentao Liu , Arun Das , Wen Meng , Yu-Chiao Chiu , Shou-Jiang Gao , Yufei Huang

In the era of information explosion, spatio-temporal data mining serves as a critical part of urban management. Considering the various fields demanding attention, e.g., traffic state, human activity, and social event, predicting multiple…

Artificial Intelligence · Computer Science 2023-09-19 Zijian Zhang , Xiangyu Zhao , Qidong Liu , Chunxu Zhang , Qian Ma , Wanyu Wang , Hongwei Zhao , Yiqi Wang , Zitao Liu

Machine learning applications on signals such as computer vision or biomedical data often face significant challenges due to the variability that exists across hardware devices or session recordings. This variability poses a Domain…

Machine Learning · Computer Science 2024-07-22 Théo Gnassounou , Antoine Collas , Rémi Flamary , Karim Lounici , Alexandre Gramfort

Spatial transcriptomics enables simultaneous measurement of gene expression and tissue morphology, offering unprecedented insights into cellular organization and disease mechanisms. However, the field lacks comprehensive benchmarks for…

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

Spatial-temporal graph learning has emerged as a promising solution for modeling structured spatial-temporal data and learning region representations for various urban sensing tasks such as crime forecasting and traffic flow prediction.…

Machine Learning · Computer Science 2023-06-21 Qianru Zhang , Chao Huang , Lianghao Xia , Zheng Wang , Siuming Yiu , Ruihua Han

Understanding user intent is essential for situational and context-aware decision-making. Motivated by a real-world scenario, this work addresses intent predictions of smart device users in the vicinity of vehicles by modeling sequential…

Spatio-Temporal (ST) Foundation Models (STFMs) promise cross-dataset generalization, yet joint ST pretraining is computationally expensive and grapples with the heterogeneity of domain-specific spatial patterns. Substantially extending our…

Machine Learning · Computer Science 2026-01-21 Siru Zhong , Junjie Qiu , Yangyu Wu , Yiqiu Liu , Yuanpeng He , Zhongwen Rao , Bin Yang , Chenjuan Guo , Hao Xu , Yuxuan Liang

Spatial transcriptomics measures the expression of thousands of genes in a tissue sample while preserving its spatial structure. This class of technologies has enabled the investigation of the spatial variation of gene expressions and their…

Methodology · Statistics 2025-10-23 Andrea Sottosanti , Davide Risso , Francesco Denti

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Recent advances in multi-modal AI have demonstrated promising potential for generating the currently expensive spatial transcriptomics (ST) data directly from routine histology images, offering a means to reduce the high cost and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Juming Xiong , Chongyu Qu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Daguang Xu , Yucheng Tang , Yuankai Huo

Spatial variable genes (SVGs) reveal critical information about tissue architecture, cellular interactions, and disease microenvironments. As spatial transcriptomics (ST) technologies proliferate, accurately identifying SVGs across diverse…

Applications · Statistics 2025-10-21 Jiawen Chen , Jinwei Zhang , Dongshen Peng , Yutong Song , Aitong Ruan , Yun Li , Didong Li

Multilingual speech translation (ST) and machine translation (MT) in the medical domain enhances patient care by enabling efficient communication across language barriers, alleviating specialized workforce shortages, and facilitating…

Transformer has been widely used for self-supervised pre-training in Natural Language Processing (NLP) and achieved great success. However, it has not been fully explored in visual self-supervised learning. Meanwhile, previous methods only…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Zhaowen Li , Zhiyang Chen , Fan Yang , Wei Li , Yousong Zhu , Chaoyang Zhao , Rui Deng , Liwei Wu , Rui Zhao , Ming Tang , Jinqiao Wang

Spatial Transcriptomics (ST) is a technology that measures gene expression profiles within tissue sections while retaining spatial context. It reveals localized gene expression patterns and tissue heterogeneity, both of which are essential…

Quantitative Methods · Quantitative Biology 2026-03-24 Wei Zhang , Jiajun Chu , Xinci Liu , Chen Tong , Xinyue Li
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