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A central question in neuroscience is how self-organizing dynamic interactions in the brain emerge on their relatively static structural backbone. Due to the complexity of spatial and temporal dependencies between different brain areas,…

Neurons and Cognition · Quantitative Biology 2020-10-15 Simon Wein , Wilhelm Malloni , Ana Maria Tomé , Sebastian M. Frank , Gina-Isabelle Henze , Stefan Wüst , Mark W. Greenlee , Elmar W. Lang

In healthcare, the integration of multimodal data is pivotal for developing comprehensive diagnostic and predictive models. However, managing missing data remains a significant challenge in real-world applications. We introduce MARIA…

Machine Learning · Computer Science 2026-03-13 Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

The early detection of pancreatic neoplasm is a major clinical dilemma, and it is predominantly so because tumors are likely to occur with minimal contrast margins and a large spread anatomy-wide variation amongst patients on a CT scan.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Janani Annur Thiruvengadam , Kiran Mayee Nabigaru , Anusha Kovi

Understanding the interaction patterns among simultaneous recordings of spike trains from multiple neuronal units is a key topic in neuroscience. However, an optimal approach of assessing these interactions has not been established, as…

Neurons and Cognition · Quantitative Biology 2020-12-17 Gorana Mijatovic , Yuri Antonacci , Tatjana Loncar-Turukalo , Ludovico Minati , Luca Faes

Slow Feature Analysis (SFA) extracts features representing the underlying causes of changes within a temporally coherent high-dimensional raw sensory input signal. Our novel incremental version of SFA (IncSFA) combines incremental Principal…

Artificial Intelligence · Computer Science 2012-10-11 Varun Raj Kompella , Matthew Luciw , Juergen Schmidhuber

Biological spiking neurons with intrinsic dynamics underlie the powerful representation and learning capabilities of the brain for processing multimodal information in complex environments. Despite recent tremendous progress in spiking…

Neural and Evolutionary Computing · Computer Science 2021-07-15 Mingkun Xu , Yujie Wu , Lei Deng , Faqiang Liu , Guoqi Li , Jing Pei

Third-generation artificial neural networks, Spiking Neural Networks (SNNs), can be efficiently implemented on hardware. Their implementation on neuromorphic chips opens a broad range of applications, such as machine learning-based…

Neural and Evolutionary Computing · Computer Science 2023-11-07 Elisa Nguyen , Meike Nauta , Gwenn Englebienne , Christin Seifert

The increasing need for intelligent sensors in a wide range of everyday objects requires the existence of low power information processing systems which can operate autonomously in their environment. In particular, merging and processing…

Neural and Evolutionary Computing · Computer Science 2019-03-12 Johannes C. Thiele , Olivier Bichler , Antoine Dupret , Sergio Solinas , Giacomo Indiveri

Single-cell data integration can provide a comprehensive molecular view of cells, and many algorithms have been developed to remove unwanted technical or biological variations and integrate heterogeneous single-cell datasets. Despite their…

Quantitative Methods · Quantitative Biology 2024-03-04 Rong Ma , Eric D. Sun , David Donoho , James Zou

We introduce the Conditional Self-Attention Imputation (CSAI) model, a novel recurrent neural network architecture designed to address the challenges of complex missing data patterns in multivariate time series derived from hospital…

Machine Learning · Computer Science 2026-01-07 Linglong Qian , Joseph Arul Raj , Hugh Logan Ellis , Ao Zhang , Yuezhou Zhang , Tao Wang , Richard JB Dobson , Zina Ibrahim

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

Machine Learning · Computer Science 2023-04-26 Payam Dibaeinia , Saurabh Sinha

While in recent years a number of new statistical approaches have been proposed to model group differences with a different assumption on the nature of the measurement invariance of the instruments, the tools for detecting local…

Methodology · Statistics 2022-02-04 Artur Pokropek , Ernest Pokropek

Early detection of anxiety is crucial for reducing the suffering of individuals with mental disorders and improving treatment outcomes. Utilizing an mHealth platform for anxiety screening can be particularly practical in improving screening…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Haimiao Mo , Yuchen Li , Shanlin Yang , Wei Zhang , Shuai Ding

Software vulnerability detection can be formulated as a binary classification problem that determines whether a given code snippet contains security defects. Existing multimodal methods typically fuse Natural Code Sequence (NCS)…

Software Engineering · Computer Science 2026-04-24 Yun Bian , Yi Chen , HaiQuan Wang , ShiHao Li , Zhe Cui

Recent years have witnessed the great success of blind image quality assessment (BIQA) in various task-specific scenarios, which present invariable distortion types and evaluation criteria. However, due to the rigid structure and learning…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Rui Ma , Qingbo Wu , King Ngi Ngan , Hongliang Li , Fanman Meng , Linfeng Xu

Brain-computer interfaces (BCI) in electroencephalography (EEG)-based motor imagery classification offer promising solutions in neurorehabilitation and assistive technologies by enabling communication between the brain and external devices.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Ummay Maria Muna , Md. Mehedi Hasan Shawon , Md Jobayer , Sumaiya Akter , Saifur Rahman Sabuj

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

In this paper, we present a novel framework for enhancing model interpretability by integrating heatmaps produced separately by ResNet and a restructured 2D Transformer with globally weighted input saliency. We address the critical problem…

Machine Learning · Computer Science 2025-07-02 Jiztom Kavalakkatt Francis , Matthew J Darr

Spiking Neural Network (SNN) is considered more biologically realistic and power-efficient as it imitates the fundamental mechanism of the human brain. Recently, backpropagation (BP) based SNN learning algorithms that utilize deep learning…

Neural and Evolutionary Computing · Computer Science 2022-10-11 Chengting Yu , Yangkai Du , Mufeng Chen , Aili Wang , Gaoang Wang , Erping Li

Simulation-based inference (SBI) is emerging as a new statistical paradigm for addressing complex scientific inference problems. By leveraging the representational power of deep neural networks, SBI can extract the most informative…

Instrumentation and Methods for Astrophysics · Physics 2025-10-17 Huifang Lyu , James Alvey , Noemi Anau Montel , Mauro Pieroni , Christoph Weniger