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We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Large Language Models (LLMs) demonstrate remarkable translation capabilities in high-resource language tasks, yet their performance in low-resource languages is hindered by insufficient multilingual data during pre-training. To address…

Computation and Language · Computer Science 2024-10-15 Yinquan Lu , Wenhao Zhu , Lei Li , Yu Qiao , Fei Yuan

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities in vision-language understanding tasks. While these models often produce linguistically coherent output, they often suffer from hallucinations, generating…

Computation and Language · Computer Science 2025-12-09 Sujoy Nath , Arkaprabha Basu , Sharanya Dasgupta , Swagatam Das

Although large vision-language models (LVLMs) have demonstrated remarkable capabilities, they are prone to hallucinations in multi-image tasks. We attribute this issue to limitations in existing attention mechanisms and insufficient…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Xiaochen Yang , Hao Fang , Jiawei Kong , Yaoxin Mao , Bin Chen , Shu-Tao Xia

Large language models (LLMs) are highly capable but face latency challenges in real-time applications, such as conducting online hallucination detection. To overcome this issue, we propose a novel framework that leverages a small language…

Computation and Language · Computer Science 2024-08-26 Mengya Hu , Rui Xu , Deren Lei , Yaxi Li , Mingyu Wang , Emily Ching , Eslam Kamal , Alex Deng

In this work, we introduce LLaDA-V, a purely diffusion-based Multimodal Large Language Model (MLLM) that integrates visual instruction tuning with masked diffusion models, representing a departure from the autoregressive paradigms dominant…

Machine Learning · Computer Science 2025-06-05 Zebin You , Shen Nie , Xiaolu Zhang , Jun Hu , Jun Zhou , Zhiwu Lu , Ji-Rong Wen , Chongxuan Li

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

Hallucinations in large language models (LLMs), plausible but factually inaccurate text, are often viewed as undesirable. However, recent work suggests that such outputs may hold creative potential. In this paper, we investigate whether…

Computation and Language · Computer Science 2025-08-25 Shuzhou Yuan , Zhan Qu , Ashish Yashwanth Kangen , Michael Färber

Large Vision-Language Models (LVLMs) have shown impressive performance in various tasks. However, LVLMs suffer from hallucination, which hinders their adoption in the real world. Existing studies emphasized that the strong language priors…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Zongyu Wu , Yuwei Niu , Hongcheng Gao , Minhua Lin , Zhiwei Zhang , Zhifang Zhang , Qi Shi , Yilong Wang , Sike Fu , Junjie Xu , Junjie Ao , Enyan Dai , Lei Feng , Xiang Zhang , Suhang Wang

Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

Recent advancements in massively multilingual machine translation systems have significantly enhanced translation accuracy; however, even the best performing systems still generate hallucinations, severely impacting user trust. Detecting…

Computation and Language · Computer Science 2024-10-22 Kenza Benkirane , Laura Gongas , Shahar Pelles , Naomi Fuchs , Joshua Darmon , Pontus Stenetorp , David Ifeoluwa Adelani , Eduardo Sánchez

Autoregressive Large Language Models (LLMs) have achieved impressive performance in language tasks but face two significant bottlenecks: (1) quadratic complexity in the attention module as the number of tokens increases, and (2) limited…

Computation and Language · Computer Science 2024-07-26 Haoran You , Yichao Fu , Zheng Wang , Amir Yazdanbakhsh , Yingyan Celine Lin

Multimodal large language models (MLLMs) have achieved remarkable success across diverse vision-language tasks, yet they remain highly susceptible to hallucinations, producing content that is fluent but inconsistent with visual evidence.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Youxu Shi , Suorong Yang , Dong Liu

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

Lately, researchers in artificial intelligence have been really interested in how language and vision come together, giving rise to the development of multimodal models that aim to seamlessly integrate textual and visual information.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Rajat Chawla , Arkajit Datta , Tushar Verma , Adarsh Jha , Anmol Gautam , Ayush Vatsal , Sukrit Chaterjee , Mukunda NS , Ishaan Bhola

In recent years, the rapid increase in online video content has underscored the limitations of static Video Question Answering (VideoQA) models trained on fixed datasets, as they struggle to adapt to new questions or tasks posed by newly…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Chen Cai , Zheng Wang , Jianjun Gao , Wenyang Liu , Ye Lu , Runzhong Zhang , Kim-Hui Yap

Multimodal Vision Language Models (VLMs) have emerged as a transformative topic at the intersection of computer vision and natural language processing, enabling machines to perceive and reason about the world through both visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Zongxia Li , Xiyang Wu , Hongyang Du , Fuxiao Liu , Huy Nghiem , Guangyao Shi

Despite the outstanding performance in multimodal tasks, Large Vision-Language Models (LVLMs) have been plagued by the issue of hallucination, i.e., generating content that is inconsistent with the corresponding visual inputs. While…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Bei Yan , Jie Zhang , Zheng Yuan , Shiguang Shan , Xilin Chen
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