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Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Domain adaptation, which bridges the distributions across different modalities, plays a crucial role in multimodal medical image analysis. In endoscopic imaging, combining pre-operative data with intra-operative imaging is important for…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Junyang Wu , Fangfang Xie , Jiayuan Sun , Yun Gu , Guang-Zhong Yang

Segmentation of brain structures from MRI is crucial for evaluating brain morphology, yet existing CNN and transformer-based methods struggle to delineate complex structures accurately. While current diffusion models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qilong Xing , Zikai Song , Yuteng Ye , Yuke Chen , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-10 Aasim Bin Saleem , Amr Ahmed , Ardhendu Behera , Hafeezullah Amin , Iman Yi Liao , Mahmoud Khattab , Pan Jia Wern , Haslina Makmur

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Object detection is fundamental to various real-world applications, such as security monitoring and surveillance video analysis. Despite their advancements, state-of-the-art object detectors are still vulnerable to adversarial patch…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jin Ma , Mohammed Aldeen , Christopher Salas , Feng Luo , Mashrur Chowdhury , Mert Pesé , Long Cheng

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Image generation is a prevailing technique for clinical data augmentation for advancing diagnostic accuracy and reducing healthcare disparities. Diffusion Model (DM) has become a leading method in generating synthetic medical images, but it…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Ruichen Zhang , Yuguang Yao , Zhen Tan , Zhiming Li , Pan Wang , Huan Liu , Jingtong Hu , Sijia Liu , Tianlong Chen

We propose DiRL, a Diversity-inducing Representation Learning technique for histopathology imaging. Self-supervised learning techniques, such as contrastive and non-contrastive approaches, have been shown to learn rich and effective…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Saarthak Kapse , Srijan Das , Jingwei Zhang , Rajarsi R. Gupta , Joel Saltz , Dimitris Samaras , Prateek Prasanna

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

Deepfakes pose significant security and privacy threats through malicious facial manipulations. While robust watermarking can aid in authenticity verification and source tracking, existing methods often lack the sufficient robustness…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Chen Sun , Haiyang Sun , Zhiqing Guo , Yunfeng Diao , Liejun Wang , Dan Ma , Gaobo Yang , Keqin Li

The integration of deep learning technologies in medical imaging aims to enhance the efficiency and accuracy of cancer diagnosis, particularly for pancreatic and breast cancers, which present significant diagnostic challenges due to their…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Minhee Jang , Juheon Son , Thanaporn Viriyasaranon , Junho Kim , Jang-Hwan Choi

Accurately detecting and classifying damage in analogue media such as paintings, photographs, textiles, mosaics, and frescoes is essential for cultural heritage preservation. While machine learning models excel in correcting global…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Daniela Ivanova , Marco Aversa , Paul Henderson , John Williamson

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Unsupervised anomaly detection (UAD) in medical imaging is crucial for identifying pathological abnormalities without requiring extensive labeled data. However, existing diffusion-based UAD models rely solely on imaging features, limiting…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Harim Kim , Yuhan Wang , Minkyu Ahn , Heeyoul Choi , Yuyin Zhou , Charmgil Hong

Anomaly detection is a fundamental task in machine learning and data mining, with significant applications in cybersecurity, industrial fault diagnosis, and clinical disease monitoring. Traditional methods, such as statistical modeling and…

Machine Learning · Computer Science 2025-05-09 Yi Chen

While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Daniel Bug , Steffen Schneider , Anne Grote , Eva Oswald , Friedrich Feuerhake , Julia Schüler , Dorit Merhof

Reconstruction-based approaches have achieved remarkable outcomes in anomaly detection. The exceptional image reconstruction capabilities of recently popular diffusion models have sparked research efforts to utilize them for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Haoyang He , Jiangning Zhang , Hongxu Chen , Xuhai Chen , Zhishan Li , Xu Chen , Yabiao Wang , Chengjie Wang , Lei Xie

In Recent Years, Digital Technologies Have Made Significant Strides In Augmenting-Human-Health, Cognition, And Perception, Particularly Within The Field Of Computational-Pathology. This Paper Presents A Novel Approach To Enhancing The…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xiaoqian Hu
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