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Background: In epidemiology, causal inference and prediction modeling methodologies have been historically distinct. Directed Acyclic Graphs (DAGs) are used to model a priori causal assumptions and inform variable selection strategies for…

Methodology · Statistics 2020-07-03 Marco Piccininni , Stefan Konigorski , Jessica L Rohmann , Tobias Kurth

Directed acyclic graphs (DAGs) are commonly used to model causal relationships among random variables. In general, learning the DAG structure is both computationally and statistically challenging. Moreover, without additional information,…

Machine Learning · Statistics 2024-03-26 Ali Shojaie , Wenyu Chen

Directed acyclic graphs (DAGs) constitute a central modeling tool to enable principled reasoning about cause-effect interactions in complex systems. However, since the causal structure underlying a group of variables is often unknown and…

Machine Learning · Statistics 2026-05-25 Gonzalo Mateos , Samuel Rey , Hamed Ajorlou , Mariano Tepper

Causal inference with observational data critically relies on untestable and extra-statistical assumptions that have (sometimes) testable implications. Well-known sets of assumptions that are sufficient to justify the causal interpretation…

Methodology · Statistics 2024-02-20 Pablo Geraldo Bastías

Assuming a directed acyclic graph (DAG) that represents prior knowledge of causal relationships between variables is a common starting point for cause-effect estimation. Existing literature typically invokes hypothetical domain expert…

Machine Learning · Statistics 2025-03-11 Kirtan Padh , Zhufeng Li , Cecilia Casolo , Niki Kilbertus

This paper considers inference of causal structure in a class of graphical models called "conditional DAGs". These are directed acyclic graph (DAG) models with two kinds of variables, primary and secondary. The secondary variables are used…

Methodology · Statistics 2014-11-12 Chris J. Oates , Jim Q. Smith , Sach Mukherjee

We consider the problem of learning the underlying causal structure among a set of variables, which are assumed to follow a Bayesian network or, more specifically, a linear recursive structural equation model (SEM) with the associated…

Statistics Theory · Mathematics 2025-08-05 Anamitra Chaudhuri , Anirban Bhattacharya , Yang Ni

Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal…

Methodology · Statistics 2024-08-14 Carlo Berzuini , Davide Luciani , Hiren C. Patel

The feed-forward relationship naturally observed in time-dependent processes and in a diverse number of real systems -such as some food-webs and electronic and neural wiring- can be described in terms of so-called directed acyclic graphs…

Physics and Society · Physics 2015-05-19 Joaquín Goñi , Bernat Corominas-Murtra , Ricard V. Solé , Carlos Rodríguez-Caso

Background: There is increasing interest in approaches for analyzing the effect of exposure mixtures on health. A key issue is how to simultaneously analyze often highly collinear components of the mixture, which can create problems such as…

Methodology · Statistics 2020-07-06 Thomas F. Webster , Marc G. Weisskopf

Causal discovery, the learning of causality in a data mining scenario, has been of strong scientific and theoretical interest as a starting point to identify "what causes what?" Contingent on assumptions and a proper learning algorithm, it…

Methodology · Statistics 2022-05-23 Gabriel Ruiz , Oscar Hernan Madrid Padilla , Qing Zhou

In this article, we propose a new hypothesis testing method for directed acyclic graph (DAG). While there is a rich class of DAG estimation methods, there is a relative paucity of DAG inference solutions. Moreover, the existing methods…

Machine Learning · Statistics 2023-05-25 Chengchun Shi , Yunzhe Zhou , Lexin Li

The use of directed acyclic graphs (DAGs) to represent conditional independence relations among random variables has proved fruitful in a variety of ways. Recursive structural equation models are one kind of DAG model. However,…

Artificial Intelligence · Computer Science 2013-02-21 Peter L. Spirtes

Directed acyclic graphical (DAG) models are a powerful tool for representing causal relationships among jointly distributed random variables, especially concerning data from across different experimental settings. However, it is not always…

Machine Learning · Statistics 2026-04-03 Francisco Madaleno , Pratik Misra , Alex Markham

There have been reports of correlation between estimates of prevalence and test accuracy across studies included in diagnostic meta-analyses. It has been hypothesized that this unexpected association arises because of certain biases…

Methodology · Statistics 2025-08-15 Yang Lu , Robert Platt , Nandini Dendukuri

Directed acyclic graphs (DAGs) are frequently used in epidemiology as a method to encode causal inference assumptions. We propose the DAGWOOD framework to bring many of those encoded assumptions to the forefront. DAGWOOD combines a root DAG…

Methodology · Statistics 2021-11-25 Noah A Haber , Mollie E Wood , Sarah Wieten , Alexander Breskin

Directed Acyclic Graphs (DAGs) are central to uncovering causal structure in complex systems, yet learning a single DAG from data is often challenging: model uncertainty, finite samples, and a combinatorially large search space frequently…

Methodology · Statistics 2026-05-19 Yunan Wu , Yue Wang , Chunlin Li , Chenglong Ye

Directed acyclic graphs (DAGs) are a class of graphs commonly used in practice, with examples that include electronic circuits, Bayesian networks, and neural architectures. While many effective encoders exist for DAGs, it remains…

Machine Learning · Computer Science 2025-05-30 Michael Sun , Orion Foo , Gang Liu , Wojciech Matusik , Jie Chen

Directed acyclic graph (DAG) learning is a central task in structure discovery and causal inference. Although the field has witnessed remarkable advances over the past few years, it remains statistically and computationally challenging to…

Machine Learning · Statistics 2026-02-09 Ryan Thompson , Edwin V. Bonilla , Robert Kohn

Causal DAGs(Directed Acyclic Graphs) are usually considered in a 2D plane. Edges indicate causal effects' directions and imply their corresponding time-passings. Due to the natural restriction of statistical models, effect estimation is…

Machine Learning · Computer Science 2023-09-26 Jia Li , Xiang Li , Xiaowei Jia , Michael Steinbach , Vipin Kumar
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