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Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Topic models have been the prominent tools for automatic topic discovery from text corpora. Despite their effectiveness, topic models suffer from several limitations including the inability of modeling word ordering information in…

Computation and Language · Computer Science 2022-02-10 Yu Meng , Yunyi Zhang , Jiaxin Huang , Yu Zhang , Jiawei Han

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

In recent years, major advancements in natural language processing (NLP) have been driven by the emergence of large language models (LLMs), which have significantly revolutionized research and development within the field. Building upon…

Computation and Language · Computer Science 2023-05-09 Hazal Türkmen , Oğuz Dikenelli , Cenk Eraslan , Mehmet Cem Çallı , Süha Süreyya Özbek

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Psychiatric intake is a sequential, high-stakes information-gathering process in which clinicians must decide what to ask, in what order, and how to interpret incomplete or ambiguous responses under limited time. Despite growing interest in…

Computation and Language · Computer Science 2026-04-29 Guan Gui , Peter Zandi , Jacob Taylor , Ananya Joshi

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

Large Language models (LLMs) have demonstrated state-of-the-art performance in various natural language processing (NLP) tasks across multiple domains, yet they are prone to shortcut learning and factual inconsistencies. This research…

Computation and Language · Computer Science 2024-04-09 Shreyasi Mandal , Ashutosh Modi

Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

Computation and Language · Computer Science 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant…

Artificial Intelligence · Computer Science 2026-01-08 Ruiqi Deng , Geoffrey Martin , Tony Wang , Gongbo Zhang , Yi Liu , Chunhua Weng , Yanshan Wang , Justin F Rousseau , Yifan Peng

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-01 Yiming Li , Fang Li , Kirk Roberts , Licong Cui , Cui Tao , Hua Xu

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

Topic models aim to reveal latent structures within a corpus of text, typically through the use of term-frequency statistics over bag-of-words representations from documents. In recent years, conceptual entities -- interpretable,…

Computation and Language · Computer Science 2024-08-27 Manuel V. Loureiro , Steven Derby , Tri Kurniawan Wijaya

Natural language processing (NLP) tasks (text classification, named entity recognition, etc.) have seen revolutionary improvements over the last few years. This is due to language models such as BERT that achieve deep knowledge transfer by…

Computation and Language · Computer Science 2021-05-27 Lee Burke , Karl Pazdernik , Daniel Fortin , Benjamin Wilson , Rustam Goychayev , John Mattingly