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Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Numerous studies have highlighted that atypical brain development, particularly during infancy and toddlerhood, is linked to an increased likelihood of being diagnosed with a neurodevelopmental condition, such as autism. Accurate brain…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Yilan Dong , Vanessa Kyriakopoulou , Irina Grigorescu , Grainne McAlonan , Dafnis Batalle , Maria Deprez

Accurate segmentation of punctate white matter lesion (PWML) in infantile brains by an automatic algorithm can reduce the potential risk of postnatal development. How to segment PWML effectively has become one of the active topics in…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Yalong Liu , Jie Li , Ying Wang , Miaomiao Wang , Xianjun Li , Zhicheng Jiao , Jian Yang , Xingbo Gao

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Zehua Ren , Yongheng Sun , Miaomiao Wang , Yuying Feng , Xianjun Li , Chao Jin , Jian Yang , Chunfeng Lian , Fan Wang

Automated fetal head segmentation in ultrasound images is critical for accurate biometric measurements in prenatal care. While existing deep learning approaches have achieved a reasonable performance, they struggle with issues like low…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Ammar Bhilwarawala , Mainak Bandyopadhyay

We introduce here a fully automated convolutional neural network-based method for brain image processing to Detect Neurons in different brain Regions during Development (DeNeRD). Our method takes a developing mouse brain as input and i)…

Computer Vision and Pattern Recognition · Computer Science 2018-07-11 Asim Iqbal , Asfandyar Sheikh , Theofanis Karayannis

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

In this paper, we propose a dual aggregation network to adaptively aggregate different information in infant brain MRI segmentation. More precisely, we added two modules based on 3D-UNet to better model information at different levels and…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Zhihao Lei , Lin Qi , Ying Wei , Yunlong Zhou

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Prenatal ultrasound evaluates fetal growth and detects congenital abnormalities during pregnancy, but the examination of ultrasound images by radiologists requires expertise and sophisticated equipment, which would otherwise fail to improve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Yang Qi , Jiaxin Cai , Jing Lu , Runqing Xiong , Rongshang Chen , Liping Zheng , Duo Ma

Introduction: Fetal resting-state functional magnetic resonance imaging (rs-fMRI) is a rapidly evolving field that provides valuable insight into brain development before birth. Accurate segmentation of the fetal brain from the surrounding…

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Segmentation of the developing fetal brain is an important step in quantitative analyses. However, manual segmentation is a very time-consuming task which is prone to error and must be completed by highly specialized indi-viduals.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-15 Kelly Payette , Raimund Kottke , Andras Jakab