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This article proposes a novel computational modeling approach for short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations, and gives a detailed overview how it fits into the framework of existing…

Computational Engineering, Finance, and Science · Computer Science 2022-08-19 Maximilian J. Grill , Wolfgang A. Wall , Christoph Meier

Training machine learning interatomic potentials (MLIPs) on total energies of molecular clusters using differential or transfer learning is becoming a popular route to extend the accuracy of correlated wave-function theory to condensed…

Chemical Physics · Physics 2025-09-23 Mikołaj J. Gawkowski , Mingjia Li , Benjamin X. Shi , Venkat Kapil

Examination of thermal expansion of two-dimensional (2D) nanomaterials is a challenging theoretical task with either ab-initio or classical molecular dynamics simulations. In this regard, while ab-initio molecular dynamics (AIMD)…

Materials Science · Physics 2021-10-22 Bohayra Mortazavi , Ali Rajabpour , Xiaoying Zhuang , Timon Rabczuk , Alexander V. Shapeev

Understanding the structure and thermodynamics of solvated ions is essential for advancing applications in electrochemistry, water treatment, and energy storage. While ab initio molecular dynamics methods are highly accurate, they are…

Chemical Physics · Physics 2025-07-15 Ademola Soyemi , Tibor Szilvasi

In an era where symbolic mathematical equations are indispensable for modeling complex natural phenomena, scientific inquiry often involves collecting observations and translating them into mathematical expressions. Recently, deep learning…

Machine Learning · Computer Science 2024-03-18 Kazem Meidani , Parshin Shojaee , Chandan K. Reddy , Amir Barati Farimani

Machine Learned Interatomic Potentials (MLIPs) offer a powerful combination of abilities for accelerating theoretical spectroscopy calculations utilising both ensemble sampling and trajectory post-processing for inclusion of vibronic…

Chemical Physics · Physics 2025-10-23 Jacob Eller , Nicholas D. M. Hine

The sustainable production of many bulk chemicals relies on heterogeneous catalysis. The rational design or improvement of the required catalysts critically depends on insights into the underlying mechanisms at the atomic scale. In recent…

Chemical Physics · Physics 2024-11-04 Amir Omranpour , Jan Elsner , K. Nikolas Lausch , Jörg Behler

Uranium monocarbide (UC) is an advanced ceramic fuel candidate due to its superior uranium density and thermal conductivity compared to traditional fuels. To accurately model UC at reactor operating conditions, we developed a machine…

Universal machine-learned interatomic potentials (U-MLIPs) have demonstrated effectiveness across diverse atomistic systems but often require fine-tuning for task-specific accuracy. We investigate the fine-tuning of two MACE-based…

Computational Physics · Physics 2025-06-10 Xiaoqing Liu , Kehan Zeng , Yangshuai Wang , Teng Zhao

Prediction of protein-ligand interactions (PLI) plays a crucial role in drug discovery as it guides the identification and optimization of molecules that effectively bind to target proteins. Despite remarkable advances in deep…

Biomolecules · Quantitative Biology 2023-07-18 Seokhyun Moon , Sang-Yeon Hwang , Jaechang Lim , Woo Youn Kim

The prediction of protein interactions (CPIs) is crucial for the in-silico screening step in drug discovery. Recently, many end-to-end representation learning methods using deep neural networks have achieved significantly better performance…

Quantitative Methods · Quantitative Biology 2020-11-30 Jingtao Wang , Xi Li , Hua Zhang

Machine-learned interatomic potentials (MLIPs) promise to significantly advance atomistic simulations by delivering quantum-level accuracy for large molecular systems at a fraction of the computational cost of traditional electronic…

The advent of machine learning in materials science opens the way for exciting and ambitious simulations of large systems and long time scales with the accuracy of ab-initio calculations. Recently, several pre-trained universal machine…

Materials Science · Physics 2024-06-28 Luis Casillas-Trujillo , Abhijith S. Parackal , Rickard Armiento , Björn Alling

Emerging machine learning interatomic potentials (MLIPs) offer a promising solution for large-scale accurate material simulations, but stringent tests related to the description of vibrational dynamics in molecular crystals remain scarce.…

Materials Science · Physics 2025-04-17 Burak Gurlek , Shubham Sharma , Paolo Lazzaroni , Angel Rubio , Mariana Rossi

Machine-learned interatomic potentials (MLIPs) promise to provide near density-functional theory accuracy at a fraction of the computational cost, offering a transformative route toward genuinely predictive chemistry. Yet their predictive…

Materials Science · Physics 2026-03-06 Jeff Armstrong , Adam Jackson , Alin Elena

Machine learning interatomic potentials (MLIPs) often neglect long-range interactions, such as electrostatic and dispersion forces. In this work, we introduce a straightforward and efficient method to account for long-range interactions by…

Machine Learning · Computer Science 2024-12-20 Bingqing Cheng

Machine learning components commonly appear in larger decision-making pipelines; however, the model training process typically focuses only on a loss that measures accuracy between predicted values and ground truth values. Decision-focused…

Machine Learning · Computer Science 2019-07-19 Aaron Ferber , Bryan Wilder , Bistra Dilkina , Milind Tambe

The highly anisotropic thermal conductivity in layered materials is crucial for a broad range of applications such as thermal management of electronic devices, thermal insulation, and thermoelectrics. Understanding of anisotropic thermal…

Materials Science · Physics 2022-08-23 Jialin Tang , Qi Wang , Jiongzhi Zheng , Lin Cheng , Ruiqiang Guo

We describe the development of machine-learned potentials of atmospheric gases with flexible monomers for molecular simulations. A recently suggested permutationally invariant polynomial neural network (PIP-NN) approach is utilized to…

Chemical Physics · Physics 2025-04-21 Artem Finenko

Machine learned interatomic potentials (MLIPs) are becoming a standard method for DFT-level accurate molecular dynamics simulation and large-scale studies of crystal energetics. Increasingly popular are universal pre-trained potentials,…

Materials Science · Physics 2026-02-03 Abhijith S Parackal , Rickard Armiento , Florian Trybel