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The Electronic Health Record (EHR) is an essential part of the modern medical system and impacts healthcare delivery, operations, and research. Unstructured text is attracting much attention despite structured information in the EHRs and…

Computation and Language · Computer Science 2023-06-29 Irene Li , Keen You , Yujie Qiao , Lucas Huang , Chia-Chun Hsieh , Benjamin Rosand , Jeremy Goldwasser , Dragomir Radev

Radiologists must utilize multiple modal images for tumor segmentation and diagnosis due to the limitations of medical imaging and the diversity of tumor signals. This leads to the development of multimodal learning in segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuyun Shen , Wenhao Li , Haoqing Chen , Xiaoling Wang , Fengping Zhu , Yuxin Li , Xiangfeng Wang , Bo Jin

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

Machine Learning · Computer Science 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

Large-scale clinical databases offer opportunities for medical research, but their complexity creates barriers to effective use. The Medical Information Mart for Intensive Care (MIMIC-IV), one of the world's largest open-source electronic…

Information Retrieval · Computer Science 2026-05-21 Rafi Al Attrach , Pedro Moreira , Rajna Fani , Renato Umeton , Amelia Fiske , Leo Anthony Celi

Multimodal AI has demonstrated superior performance over unimodal approaches by leveraging diverse data sources for more comprehensive analysis. However, applying this effectiveness in healthcare is challenging due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Pranav Poudel , Prashant Shrestha , Sanskar Amgain , Yash Raj Shrestha , Prashnna Gyawali , Binod Bhattarai

While existing critical care EHR datasets such as MIMIC and eICU have enabled significant advances in clinical AI research, the CRITICAL dataset opens new frontiers by providing extensive scale and diversity -- containing 1.95 billion…

Machine Learning · Computer Science 2025-09-24 Xiaolong Luo , Michael Lingzhi Li

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly…

Background and Objective: Deep learning enables tremendous progress in medical image analysis. One driving force of this progress are open-source frameworks like TensorFlow and PyTorch. However, these frameworks rarely address issues…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Alain Jungo , Olivier Scheidegger , Mauricio Reyes , Fabian Balsiger

Multimodal federated learning holds immense potential for collaboratively training models from multiple sources without sharing raw data, addressing both data scarcity and privacy concerns, two key challenges in healthcare. A major…

Machine Learning · Computer Science 2025-05-27 Pranav Poudel , Aavash Chhetri , Prashnna Gyawali , Georgios Leontidis , Binod Bhattarai

Evaluating the computational reproducibility of data analysis pipelines has become a critical issue. It is, however, a cumbersome process for analyses that involve data from large populations of subjects, due to their computational and…

Methodology · Statistics 2018-09-28 Soudabeh Barghi , Lalet Scaria , Ali Salari , Tristan Glatard

The clinical trial is a pivotal and costly process, often spanning multiple years and requiring substantial financial resources. Therefore, the development of clinical trial outcome prediction models aims to exclude drugs likely to fail and…

Machine Learning · Computer Science 2025-01-29 Wenhao Zheng , Liaoyaqi Wang , Dongshen Peng , Hongxia Xu , Yun Li , Hongtu Zhu , Tianfan Fu , Huaxiu Yao

Advances in data collection enable the capture of rich patient-generated data: from passive sensing (e.g., wearables and smartphones) to active self-reports (e.g., cross-sectional surveys and ecological momentary assessments). Although…

Disease diagnosis is a central pillar of modern healthcare, enabling early detection and timely intervention for acute conditions while guiding lifestyle adjustments and medication regimens to prevent or slow chronic disease. Self-reports…

Computation and Language · Computer Science 2025-11-10 Yuexin Wu , Shiqi Wang , Vasile Rus

Currently, a variety of pipeline tools are available for use in data engineering. Data scientists can use these tools to resolve data wrangling issues associated with data and accomplish some data engineering tasks from data ingestion…

Machine Learning · Computer Science 2024-06-21 Anthony Mbata , Yaji Sripada , Mingjun Zhong

Currently, medical vision language models are widely used in medical vision question answering tasks. However, existing models are confronted with two issues: for input, the model only relies on text instructions and lacks direct…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yanyuan Chen , Dexuan Xu , Yu Huang , Songkun Zhan , Hanpin Wang , Dongxue Chen , Xueping Wang , Meikang Qiu , Hang Li

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

Computation and Language · Computer Science 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

Many healthcare applications are inherently multimodal, involving several physiological signals. As sensors for these signals become more common, improving machine learning methods for multimodal healthcare data is crucial. Pretraining…

Machine Learning · Computer Science 2024-10-23 Ching Fang , Christopher Sandino , Behrooz Mahasseni , Juri Minxha , Hadi Pouransari , Erdrin Azemi , Ali Moin , Ellen Zippi