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Latent representations of drugs and their targets produced by contemporary graph autoencoder models have proved useful in predicting many types of node-pair interactions on large networks, including drug-drug, drug-target, and target-target…
Neuroscience research publications encompass a vast wealth of knowledge. Accurately retrieving existing information and discovering new insights from this extensive literature is essential for advancing the field. However, when knowledge is…
Knowledge Graphs (KGs) serving as semantic networks, prove highly effective in managing complex interconnected data in different domains, by offering a unified, contextualized, and structured representation with flexibility that allows for…
Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…
Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…
Learning low-dimensional embeddings of knowledge graphs is a powerful approach used to predict unobserved or missing edges between entities. However, an open challenge in this area is developing techniques that can go beyond simple edge…
Retrieval-augmented generation (RAG) enables large language models (LLMs) to dynamically access external information, which is powerful for answering questions over previously unseen documents. Nonetheless, they struggle with high-level…
With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge.…
Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…
Molecular interaction prediction plays a crucial role in forecasting unknown interactions between molecules, such as drug-target interaction (DTI) and drug-drug interaction (DDI), which are essential in the field of drug discovery and…
Knowledge Graph-based Retrieval-Augmented Generation (KG-RAG) significantly enhances the reasoning capabilities of LargeLanguage Models by leveraging structured knowledge. However, existing KG-RAG frameworks typically operate as open-loop…
Knowledge Graphs (KGs), representing facts as triples, have been widely adopted in many applications. Reasoning tasks such as link prediction and rule induction are important for the development of KGs. Knowledge Graph Embeddings (KGEs)…
Knowledge Graphs (KGs), as structured knowledge bases that organize relational information across diverse domains, provide a unified semantic foundation for cross-domain recommendation (CDR). By integrating symbolic knowledge with user-item…
Graph Retrieval-Augmented Generation (Graph RAG) effectively builds a knowledge graph (KG) to connect disparate facts across a large document corpus. However, this broad-view approach often lacks the deep structured reasoning needed for…
Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…
Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…
Entity alignment is a basic and vital technique in knowledge graph (KG) integration. Over the years, research on entity alignment has resided on the assumption that KGs are static, which neglects the nature of growth of real-world KGs. As…
Real-world knowledge graphs (KG) are mostly incomplete. The problem of recovering missing relations, called KG completion, has recently become an active research area. Knowledge graph (KG) embedding, a low-dimensional representation of…
In biomedical research, unified access to up-to-date domain-specific knowledge is crucial, as such knowledge is continuously accumulated in scientific literature and structured resources. Identifying and extracting specific information is a…
Knowledge graphs (KGs) store rich facts about the real world. In this paper, we study KG alignment, which aims to find alignment between not only entities but also relations and classes in different KGs. Alignment at the entity level can…