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Traditionally, pathological analysis and diagnosis are performed by manually eyeballing glass slide specimens under a microscope by an expert. The whole slide image is the digital specimen produced from the glass slide. Whole slide image…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Galib Muhammad Shahriar Himel

Efficient and effective assessment of acute and chronic wounds can help wound care teams in clinical practice to greatly improve wound diagnosis, optimize treatment plans, ease the workload and achieve health related quality of life to the…

Computers and Society · Computer Science 2021-10-13 D. M. Anisuzzaman , Chuanbo Wang , Behrouz Rostami , Sandeep Gopalakrishnan , Jeffrey Niezgoda , Zeyun Yu

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

The deployment of AI models in clinical practice faces a critical challenge: models achieving expert-level performance on benchmarks can fail catastrophically when confronted with real-world variations in medical imaging. Minor shifts in…

Artificial Intelligence · Computer Science 2025-07-09 Lukas Kuhn , Florian Buettner

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

We instruct an AI agent to construct two separate agentic AI platforms: one for autonomous training of predictive ML models for human-human and virus-human PPI, and the other for inducing explicit general rules governing human-human and…

Artificial Intelligence · Computer Science 2026-04-28 Hung N. Do , Jessica Z. Kubicek-Sutherland , Oscar A. Negrete , S. Gnanakaran

Digital pathology plays a crucial role in the development of artificial intelligence in the medical field. The digital pathology platform can make the pathological resources digital and networked, and realize the permanent storage of visual…

Human-Computer Interaction · Computer Science 2021-11-11 Jialun Wu , Anyu Mao , Xinrui Bao , Haichuan Zhang , Zeyu Gao , Chunbao Wang , Tieliang Gong , Chen Li

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Modern clinical decision support systems can concurrently serve multiple, independent medical imaging institutions, but their predictive performance may degrade across sites due to variations in patient populations, imaging hardware, and…

Artificial Intelligence · Computer Science 2025-12-23 Xavier Rafael-Palou , Jose Munuera , Ana Jimenez-Pastor , Richard Osuala , Karim Lekadir , Oliver Diaz

Alzheimer's disease (AD) presents a complex, multifaceted challenge to patients, caregivers, and the healthcare system, necessitating integrated and dynamic support solutions. While artificial intelligence (AI) offers promising avenues for…

Multiagent Systems · Computer Science 2025-10-13 Adib Bazgir , Amir Habibdoust , Xing Song , Yuwen Zhang

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Systematic literature reviews are essential for synthesizing scientific evidence but are costly, difficult to scale and time-intensive, creating bottlenecks for evidence-based policy. We study whether large language models can automate the…

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

Artificial Intelligence · Computer Science 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Automated pathology image analysis is central to clinical diagnosis, but clinicians still ask which slide features drive a model's decision and why. Vision-language models can produce natural language explanations, but these are often…

Artificial Intelligence · Computer Science 2026-01-06 Kewen Cao , Jianxu Chen , Yongbing Zhang , Ye Zhang , Hongxiao Wang

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj

The paper presents a detailed Agentic Artificial Intelligence (AI) model that would enable people with disabilities and neurodivergence to lead healthier lives and have more regular days. The system will use a multi-layer structure; it will…

Artificial Intelligence · Computer Science 2025-12-01 Salman Jan , Toqeer Ali Syed , Gohar Ali , Ali Akarma , Mohammad Riyaz Belgaum , Ahmad Ali

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor
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