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High quality real world datasets are essential for advancing data driven approaches in type 1 diabetes (T1D) management, including personalized therapy design, digital twin systems, and glucose prediction models. However, progress in this…

Machine Learning · Computer Science 2025-06-19 Saman Khamesian , Asiful Arefeen , Bithika M. Thompson , Maria Adela Grando , Hassan Ghasemzadeh

Background: Type 1 diabetes (T1D) has seen a rapid evolution in management technology and forms a useful case study for the future management of other chronic conditions. Further development of this management technology requires an…

Human-Computer Interaction · Computer Science 2025-07-25 Sam Gordon James , Miranda Elaine Glynis Armstrong , Aisling Ann O'Kane , Harry Emerson , Zahraa S. Abdallah

Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…

Machine Learning · Computer Science 2023-10-24 Harry Emerson , Ryan McConville , Matthew Guy

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

Artificial intelligence (AI) algorithms are a critical part of state-of-the-art digital health technology for diabetes management. Yet, access to large high-quality datasets is creating barriers that impede development of robust AI…

Artificial Intelligence · Computer Science 2025-07-21 Temiloluwa Prioleau , Baiying Lu , Yanjun Cui

Simulating glucose dynamics in individuals with type 1 diabetes (T1D) is critical for developing personalized treatments and supporting data-driven clinical decisions. Existing models often miss key physiological aspects and are difficult…

Quantitative Methods · Quantitative Biology 2026-04-16 Valentina Roquemen-Echeverri , Taisa Kushner , Peter G. Jacobs , Clara Mosquera-Lopez

Newly diagnosed Type 1 Diabetes (T1D) patients often struggle to obtain effective Blood Glucose (BG) prediction models due to the lack of sufficient BG data from Continuous Glucose Monitoring (CGM), presenting a significant "cold start"…

Machine Learning · Computer Science 2024-06-24 Chengzhe Piao , Taiyu Zhu , Yu Wang , Stephanie E Baldeweg , Paul Taylor , Pantelis Georgiou , Jiahao Sun , Jun Wang , Kezhi Li

Type 1 Diabetes (T1D) is a chronic condition where the body produces little or no insulin, a hormone required for the cells to use blood glucose (BG) for energy and to regulate BG levels in the body. Finding the right insulin dose and time…

Machine Learning · Computer Science 2024-11-28 Isabella Degen , Zahraa S. Abdallah

Individualized therapy is driven forward by medical data analysis, which provides insight into the patient's context. In particular, for Type 1 Diabetes (T1D), which is an autoimmune disease, relationships between demographics, sensor data,…

Signal Processing · Electrical Eng. & Systems 2026-04-23 Beyza Cinar , Maria Maleshkova

Objective digital data is scarce yet needed in many domains to enable research that can transform the standard of healthcare. While data from consumer-grade wearables and smartphones is more accessible, there is critical need for similar…

Computers and Society · Computer Science 2023-09-20 Temiloluwa Prioleau , Abigail Bartolome , Richard Comi , Catherine Stanger

Diabetes devices, including Continuous Glucose Monitoring (CGM), Smart Insulin Pens, and Automated Insulin Delivery systems, generate rich time-series data widely used in research and machine learning. However, inconsistent data formats…

Machine Learning · Computer Science 2026-04-15 Elliott C. Pryor , Marc D. Breton , Anas El Fathi

Diabetes remains a significant health challenge globally, contributing to severe complications like kidney disease, vision loss, and heart issues. The application of machine learning (ML) in healthcare enables efficient and accurate disease…

Machine Learning · Computer Science 2025-05-13 Mahade Hasan , Farhana Yasmin

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

Machine Learning · Computer Science 2025-11-27 Mirko Paolo Barbato , Giorgia Rigamonti , Davide Marelli , Paolo Napoletano

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

Machine Learning · Computer Science 2019-07-30 Ramin Ramazi , Christine Perndorfer , Emily Soriano , Jean-Philippe Laurenceau , Rahmatollah Beheshti

Data-driven models for glucose level forecast often do not provide meaningful insights despite accurate predictions. Yet, context understanding in medicine is crucial, in particular for diabetes management. In this paper, we introduce…

Machine Learning · Computer Science 2021-11-16 Quentin Blampey , Mehdi Rahim

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review…

Machine Learning · Computer Science 2023-05-29 Farida Mohsen , Hamada R. H. Al-Absi , Noha A. Yousri , Nady El Hajj , Zubair Shah

Type 1 diabetes (T1D) is a highly metabolically heterogeneous disease that cannot be adequately characterized by conventional biomarkers such as glycated hemoglobin (HbA1c). This study proposes an explainable deep learning framework that…

Machine Learning · Computer Science 2026-01-09 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba , Sule Yildrim Yayilgan , Sarang Shaikh

Type 2 diabetes mellitus (T2DM) is one of the most common diseases and a leading cause of death. The problem of early diagnosis of T2DM is challenging and necessary to prevent serious complications. This study proposes a novel neural…

Machine Learning · Computer Science 2023-01-20 Tayyab Nasir , Muhammad Kamran Malik

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens
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