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There have been multiple attempts to demonstrate that quantum annealing and, in particular, quantum annealing on quantum annealing machines, has the potential to outperform current classical optimization algorithms implemented on CMOS…

Quantum computing has shown significant potential to address complex optimization problems; however, its application remains confined to specific problems at limited scales. Spatial regionalization remains largely unexplored in quantum…

Emerging Technologies · Computer Science 2025-07-29 Yunhan Chang , Amr Magdy , Federico M. Spedalieri , Ibrahim Sabek

Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

Quantum computing holds transformative potential for medical applications, yet efficiently preparing quantum states from complex medical data remains a fundamental challenge. This survey provides a comprehensive examination of current…

Quantum Physics · Physics 2025-08-08 Nikhil Kumar Rajput , Riya Bansal

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

A novel class of hybrid quantum-classical algorithms based on the variational approach have recently emerged from separate proposals addressing, for example, quantum chemistry and combinatorial problems. These algorithms provide an…

Quantum Physics · Physics 2017-01-09 Gian Giacomo Guerreschi , Mikhail Smelyanskiy

Quantum computational approaches to some classic target identification and localization algorithms, especially for radar images, are investigated, and are found to raise a number of quantum statistics and quantum measurement issues with…

Quantum Physics · Physics 2021-05-05 Peter B. Weichman

Quantum computing promises polynomial and exponential speedups in many domains, such as unstructured search and prime number factoring. However, quantum programs yield probabilistic outputs from exponentially growing distributions and are…

Software Engineering · Computer Science 2024-10-29 Noah H. Oldfield , Christoph Laaber , Tao Yue , Shaukat Ali

Variational quantum algorithms (VQAs) have the potential of utilizing near-term quantum machines to gain certain computational advantages over classical methods. Nevertheless, modern VQAs suffer from cumbersome computational overhead,…

Quantum Physics · Physics 2021-06-25 Yuxuan Du , Yang Qian , Dacheng Tao

Patient stratification identifying clinically meaningful subgroups is essential for advancing personalized medicine through improved diagnostics and treatment strategies. Electronic health records (EHRs), particularly those from intensive…

Machine Learning · Computer Science 2025-06-09 Dimitrios Proios , Alban Bornet , Anthony Yazdani , Jose F Rodrigues , Douglas Teodoro

Large quantum computers promise to solve some critical problems not solvable otherwise. However, modern quantum technologies suffer various imperfections such as control errors and qubit decoherence, inhibiting their potential utility. The…

Quantum Physics · Physics 2023-01-19 Andrii Maksymov , Jason Nguyen , Yunseong Nam , Igor Markov

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

Quantum Physics · Physics 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

Controlled experiments are widely used in many applications to investigate the causal relationship between input factors and experimental outcomes. A completely randomized design is usually used to randomly assign treatment levels to…

Methodology · Statistics 2026-05-12 Yiou Li , Lulu Kang , Xiao Huang

Optimization theory has been widely studied in academia and finds a large variety of applications in industry. The different optimization models in their discrete and/or continuous settings have catered to a rich source of research…

Quantum Physics · Physics 2026-03-16 Debbie Lim , Joao F. Doriguello , Patrick Rebentrost

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

In the realm of precision medicine, effective patient stratification and disease subtyping demand innovative methodologies tailored for multi-omics data. Clustering techniques applied to multi-omics data have become instrumental in…

Machine Learning · Computer Science 2024-01-30 Bastian Pfeifer , Christel Sirocchi , Marcus D. Bloice , Markus Kreuzthaler , Martin Urschler

In both the fields of computer science and medicine there is very strong interest in developing personalized treatment policies for patients who have variable responses to treatments. In particular, I aim to find an optimal personalized…

Machine Learning · Computer Science 2014-07-01 Yousuf M. Soliman

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution. Quantum computation is a new computational paradigm which exploits quantum resources to speed up information processing tasks. Therefore, it is…

Quantum Physics · Physics 2023-02-20 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

The advent of quantum algorithms has initiated a discourse on the potential for quantum speedups for optimization problems. However, several factors still hinder a practical realization of the potential benefits. These include the lack of…