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In this paper, we obtain bounds on the probability of convergence to the optimal solution for the compact Genetic Algorithm (cGA) and the Population Based Incremental Learning (PBIL). We also give a sufficient condition for convergence of…

Neural and Evolutionary Computing · Computer Science 2010-09-14 Reza Rastegar

Conventional methods for analyzing composite endpoints in clinical trials often only focus on the time to the first occurrence of all events in the composite. Therefore, they have inherent limitations because the individual patients' first…

Methodology · Statistics 2022-11-29 Jialu Wang , Yeh-Fong Chen , Thomas Gwise

For many important problems the quantity of interest is an unknown function of the parameters, which is a random vector with known statistics. Since the dependence of the output on this random vector is unknown, the challenge is to identify…

Machine Learning · Statistics 2021-04-28 Themistoklis P. Sapsis

We present a unified framework ensuring well posedness and providing stability estimates to a class of Initial Boundary Value Problems for renewal equations comprising a variety of biological or epidemiological models. This versatility is…

Analysis of PDEs · Mathematics 2023-01-05 Rinaldo M. Colombo , Mauro Garavello , Francesca Marcellini , Elena Rossi

We analyze common types of e-variables and e-processes for composite exponential family nulls: the optimal e-variable based on the reverse information projection (RIPr), the conditional (COND) e-variable, and the universal inference (UI)…

Methodology · Statistics 2025-08-27 Yunda Hao , Peter Grünwald

Regression models are essential for a wide range of real-world applications. However, in practice, target values are not always precisely known; instead, they may be represented as intervals of acceptable values. This challenge has led to…

Machine Learning · Computer Science 2025-12-08 Tung L Nguyen , Toby Dylan Hocking

For many tasks of data analysis, we may only have the information of the explanatory variable and the evaluation of the response values are quite expensive. While it is impractical or too costly to obtain the responses of all units, a…

Computation · Statistics 2023-04-07 Wei Zheng , Ting Tian , Xueqin Wang

This paper investigates and bounds the expected solution quality of combinatorial optimization problems when feasible solutions are chosen at random. Loose general bounds are discovered, as well as families of combinatorial optimization…

Data Structures and Algorithms · Computer Science 2014-02-04 Evan A. Sultanik

The choice of the parameter value for regularized inverse problems is critical to the results and remains a topic of interest. This article explores a criterion for selecting a good parameter value by maximizing the probability of the data,…

Numerical Analysis · Mathematics 2020-02-11 Toby Sanders , Rodrigo B. Platte , Robert D. Skeel

We derive adjusted signed likelihood ratio statistics for a general class of extreme value regression models. The adjustments reduce the error in the standard normal approximation to the distribution of the signed likelihood ratio…

Statistics Theory · Mathematics 2014-05-26 Silvia L. P. Ferrari , Eliane C. Pinheiro

Optimal design of distributed decision policies can be a difficult task, illustrated by the famous Witsenhausen counterexample. In this paper we characterize the optimal control designs for the vector-valued setting assuming that it results…

Information Theory · Computer Science 2021-02-05 Maël Le Treust , Tobias Oechtering

In recent years, Machine Learning algorithms, in particular supervised learning techniques, have been shown to be very effective in solving regression problems. We compare the performance of a newly proposed regression algorithm against…

Machine Learning · Computer Science 2023-06-16 Sabina Gooljar , Kris Manohar , Patrick Hosein

We propose an estimator for the mean of random variables in separable real Banach spaces using the empirical characteristic function. Assuming that the covariance operator of the random variable is bounded in a precise sense, we show that…

Statistics Theory · Mathematics 2020-11-04 Sohail Bahmani

We consider a one-dimensional recurrent random walk in random environment (RWRE) when the environment is i.i.d. with a parametric, finitely supported distribution. Based on a single observation of the path, we provide a maximum likelihood…

Probability · Mathematics 2014-04-10 Francis Comets , Mikael Falconnet , Oleg Loukianov , Dasha Loukianova

It is well known that machine learning methods can be vulnerable to adversarially-chosen perturbations of their inputs. Despite significant progress in the area, foundational open problems remain. In this paper, we address several key…

Machine Learning · Computer Science 2024-10-30 Edgar Dobriban , Hamed Hassani , David Hong , Alexander Robey

We introduce the notion of p*-values (p*-variables), which generalizes p-values (p-variables) in several senses. The new notion has four natural interpretations: operational, probabilistic, Bayesian, and frequentist. A main example of a…

Statistics Theory · Mathematics 2022-02-24 Ruodu Wang

We study a counterfactual mean-variance optimization, where the mean and variance are defined as functionals of counterfactual distributions. The optimization problem defines the optimal resource allocation under various constraints in a…

Methodology · Statistics 2025-04-15 Kwangho Kim , Alan Mishler , José R. Zubizarreta

The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated by a single cell in which multiple mutations cooperate to…

Tissues and Organs · Quantitative Biology 2018-11-21 Philip Greulich , Benjamin D. Simons

The Negative Binomial distribution becomes highly skewed under extreme dispersion. Even at moderately large sample sizes, the sample mean exhibits a heavy right tail. The standard Normal approximation often does not provide adequate…

Methodology · Statistics 2015-03-13 David Shilane , Derek Bean

The growth rate of organisms depends both on external conditions and on internal states, such as the expression levels of various genes. We show that to achieve a criterion mean growth rate over an ensemble of conditions, the internal…

Populations and Evolution · Quantitative Biology 2007-12-31 Samuel F. Taylor , Naftali Tishby , William Bialek
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