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Intelligent agent systems based on Large Language Models (LLMs) have shown great potential in real-world applications. However, existing agent frameworks still face critical limitations in task planning and execution, restricting their…

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Engineering problem solving is central to real-world decision-making, requiring mathematical formulations that not only represent complex problems but also produce feasible solutions under data and physical constraints. Unlike mathematical…

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Large Language Models (LLMs) have shown remarkable performance on general Question Answering (QA), yet they often struggle in domain-specific scenarios where accurate and up-to-date information is required. Retrieval-Augmented Generation…

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To fully expedite AI-powered chemical research, high-quality chemical databases are the foundation. Automatic extraction of chemical information from the literature is essential for constructing reaction databases, but it is currently…

Artificial Intelligence · Computer Science 2026-03-09 Yufan Chen , Ching Ting Leung , Bowen Yu , Jianwei Sun , Yong Huang , Linyan Li , Hao Chen , Hanyu Gao

Recent advances in multimodal question answering have primarily focused on combining heterogeneous modalities or fine-tuning multimodal large language models. While these approaches have shown strong performance, they often rely on a…

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While recent advancements in Large Language Models have significantly advanced dermatological diagnosis, monolithic LLMs frequently struggle with fine-grained, large-scale multi-class diagnostic tasks and rare skin disease diagnosis owing…

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The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an efficient gene-editing system requires a deep understanding of…

Language agents have achieved considerable performance on various complex question-answering tasks by planning with external tools. Despite the incessant exploration in this field, existing language agent systems still struggle with costly,…

Computation and Language · Computer Science 2024-05-28 Shuofei Qiao , Ningyu Zhang , Runnan Fang , Yujie Luo , Wangchunshu Zhou , Yuchen Eleanor Jiang , Chengfei Lv , Huajun Chen

Large Language Models (LLMs) have demonstrated great potential in complex reasoning tasks, yet they fall short when tackling more sophisticated challenges, especially when interacting with environments through generating executable actions.…

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Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

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Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

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Recent advances in large language models have enabled AI systems to achieve expert-level performance on domain-specific scientific tasks, yet these systems remain narrow and handcrafted. We introduce SciAgent, a unified multi-agent system…

The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

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Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language interfaces. However,…

Genomics · Quantitative Biology 2026-04-08 Weicai Long , Yusen Hou , Junning Feng , Houcheng Su , Shuo Yang , Donglin Xie , Yanlin Zhang

We present WebGLM, a web-enhanced question-answering system based on the General Language Model (GLM). Its goal is to augment a pre-trained large language model (LLM) with web search and retrieval capabilities while being efficient for…

Computation and Language · Computer Science 2023-06-14 Xiao Liu , Hanyu Lai , Hao Yu , Yifan Xu , Aohan Zeng , Zhengxiao Du , Peng Zhang , Yuxiao Dong , Jie Tang

Noisy Intermediate-Scale Quantum (NISQ) devices have begun to exhibit early quantum advantages on classically intractable problems, spanning physics simulations to Gaussian boson sampling. Yet, realizing these benefits remains challenging…

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Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

Genomics · Quantitative Biology 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

Pharmaceutical patents play a vital role in biochemical industries, especially in drug discovery, providing researchers with unique early access to data, experimental results, and research insights. With the advancement of machine learning,…

Machine Learning · Computer Science 2024-10-30 Xin Wang , Yifan Zhang , Xiaojing Zhang , Longhui Yu , Xinna Lin , Jindong Jiang , Bin Ma , Kaicheng Yu

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Accurately assessing internal human states is key to understanding preferences, offering personalized services, and identifying challenges in real-world applications. Originating from psychometrics, adaptive testing has become the…

Artificial Intelligence · Computer Science 2025-06-04 Junhao Yu , Yan Zhuang , YuXuan Sun , Weibo Gao , Qi Liu , Mingyue Cheng , Zhenya Huang , Enhong Chen