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We formulate a general, high-dimensional kinetic theory describing the internal state (such as gene expression or protein levels) of cells in a stochastically evolving population. The resolution of our kinetic theory also allows one to…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Tom Chou

Accurate crowd simulation is crucial for public safety management, emergency evacuation planning, and intelligent transportation systems. However, existing methods, which typically model crowds as a collection of independent individual…

Machine Learning · Computer Science 2026-04-14 Zijin Liu , Xu Geng , Wenshuai Xu , Xiang Zhao , Yan Xia , You Song

We consider a model for Darwinian evolution in an asexual population with a large but non-constant populations size characterized by a natural birth rate, a logistic death rate modelling competition and a probability of mutation at each…

Probability · Mathematics 2015-08-28 Martina Baar , Anton Bovier , Nicolas Champagnat

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

Populations and Evolution · Quantitative Biology 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

In this article, a stochastic individual-based model describing Darwinian evolution of asexual, phenotypic trait-structured population, is studied. We consider a large population with constant population size characterised by a resampling…

Probability · Mathematics 2024-07-09 Nicolas Champagnat , Vincent Hass

We analyse metapopulation dynamics in terms of an individual-based, stochastic model of a finite metapopulation. We suggest a new approach, using the number of patches in the population as a large parameter. This approach does not require…

Populations and Evolution · Quantitative Biology 2013-03-05 A. Eriksson , F. Elias-Wolff , B. Mehlig

Trajectory-based methods are well-developed to approximate steady-state probability distributions for stochastic processes in large-system limits. The trajectories are solutions to equations of motion of Hamiltonian dynamical systems, and…

Statistical Mechanics · Physics 2021-05-26 Eric Smith , Supriya Krishnamurthy

We discuss several models of the dynamics of interacting populations. The models are constructed by nonlinear differential equations and have two sets of parameters: growth rates and coefficients of interaction between populations. We…

Adaptation and Self-Organizing Systems · Physics 2013-07-29 Nikolay K. Vitanov , Zlatinka I. Dimitrova

Isomorphism of the two-state system is heuristic in understanding the dynamical or statistical behavior of the simplest yet most quantum system that has no classical counterpart. We use the constraint phase space developed in J. Chem. Phys.…

Quantum Physics · Physics 2024-05-22 Xiangsong Cheng , Xin He , Jian Liu

The goal of this paper is to provide mathematically rigorous tools for modelling the evolution of a community of interacting individuals. We model the population by a measure space where the measure determines the abundance of individual…

Probability · Mathematics 2017-05-17 Thomas Cass , Terry Lyons

Synthetic population is an increasingly important material used in numerous areas such as urban and transportation analysis. Traditional methods such as iterative proportional fitting (IPF) is not capable of generating high-quality data…

Computers and Society · Computer Science 2025-08-14 Hai Yang , Hongying Wu , Linfei Yuan , Xiyuan Ren , Joseph Y. J. Chow , Jinqin Gao , Kaan Ozbay

The internally electrodynamic (IED) particle model was derived based on overall experimental observations, with the IED process itself being built directly on three experimental facts, a) electric charges present with all material…

General Physics · Physics 2011-04-07 J. X. Zheng-Johansson

This article presents a comprehensive study of the continuous McKendrick model, which serves as a foundational framework in population dynamics and epidemiology. The model is formulated through partial differential equations that describe…

Populations and Evolution · Quantitative Biology 2026-01-23 Dragos-Patru Covei

We present a novel method for solving population density equations (PDEs), where the populations can be subject to non-Markov noise for arbitrary distributions of jump sizes. The method combines recent developments in two different…

Biological Physics · Physics 2017-06-28 Yi Ming Lai , Marc de Kamps

Under certain conditions, the dynamics of coarse-grained models of solvated proteins can be described using a Markov state model, which tracks the evolution of populations of configurations. The transition rates among states that appear in…

Soft Condensed Matter · Physics 2022-09-26 Margarita Colberg , Jeremy Schofield

Predictive statistical mechanics is a form of inference from available data, without additional assumptions, for predicting reproducible phenomena. By applying it to systems with Hamiltonian dynamics, a problem of predicting the macroscopic…

Statistical Mechanics · Physics 2015-09-22 Domagoj Kuic

Interacting-Particle Reaction Dynamics (iPRD) simulates the spatiotemporal evolution of particles that experience interaction forces and can react with one another. The combination of interaction forces and reactions enable a wide range of…

Chemical Physics · Physics 2018-07-20 Christoph Fröhner , Frank Noé

Populations interact non-linearly and are influenced by environmental fluctuations. In order to have realistic mathematical models, one needs to take into account that the environmental fluctuations are inherently stochastic. Often,…

Probability · Mathematics 2025-07-29 Alexandru Hening , Siddharth Sabharwal

For population systems modeled by age-structured hyperbolic partial differential equations (PDEs) that are bilinear in the input and evolve with a positive-valued infinite-dimensional state, global stabilization of constant yield set points…

Optimization and Control · Mathematics 2017-04-03 Kevin Schmidt , Iasson Karafyllis , Miroslav Krstic

There exists a wide variety of works on the dynamics of large populations ranging from simple heuristic modeling to those based on advanced computer supported methods. Their interconnections, however, remain mostly vague, which…

Dynamical Systems · Mathematics 2023-04-27 Yuri Kozitsky , Krzysztof Pilorz
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