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Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge

Automated skin lesion analysis for simultaneous detection and recognition is still challenging for inter-class homogeneity and intra-class heterogeneity, leading to low generic capability of a Single Convolutional Neural Network (CNN) with…

Modern text-to-image diffusion models encode rich visual priors, but expose them only through one-way text-conditioned generation. Existing unified vision--language models derived from them recover bidirectional capability through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Eric Tillmann Bill , Enis Simsar , Alessio Tonioni , Thomas Hofmann

Existing Medical Large Vision-Language Models (Med-LVLMs), encapsulating extensive medical knowledge, demonstrate excellent capabilities in understanding medical images. However, there remain challenges in visual localization in medical…

Computation and Language · Computer Science 2025-06-03 Yucheng Zhou , Lingran Song , Jianbing Shen

Reinforcement learning (RL) has become the pivotal post-training technique for large language model (LLM). Effectively scaling reinforcement learning is now the key to unlocking advanced reasoning capabilities and ensuring safe,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-10 Zhixin Wang , Tianyi Zhou , Liming Liu , Ao Li , Jiarui Hu , Dian Yang , Yinhui Lu , Jinlong Hou , Siyuan Feng , Yuan Cheng , Yuan Qi

In the field of healthcare, precise skin lesion segmentation is crucial for the early detection and accurate diagnosis of skin diseases. Despite significant advances in deep learning for image processing, existing methods have yet to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Siyu Wang , Hua Wang , Huiyu Li , Fan Zhang

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

Robust generalization beyond training distributions remains a critical challenge for deep neural networks. This is especially pronounced in medical image analysis, where data is often scarce and covariate shifts arise from different…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Francesco Di Salvo , Sebastian Doerrich , Jonas Alle , Christian Ledig

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

With the widespread application of artificial intelligence (AI), particularly deep learning (DL) and vision large language models (VLLMs), in skin disease diagnosis, the need for interpretability becomes crucial. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Yuhao Shen , Liyuan Sun , Yan Xu , Wenbin Liu , Shuping Zhang , Shawn Afvari , Zhongyi Han , Jiaoyan Song , Yongzhi Ji , Tao Lu , Xiaonan He , Xin Gao , Juexiao Zhou

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Mirza Ahsan Ullah , Tehseen Zia

Large vision-language models (LVLMs) demonstrate strong performance in dermatology; however, evaluating diagnostic reasoning for rare conditions remains largely unexplored. Existing benchmarks focus on common diseases and assess only final…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yang Liu , Jiyao Yang , Hongjin Zhao , Xiaoyong Li , Yanzhe Ji , Xingjian Li , Runmin Jiang , Tianyang Wang , Saeed Anwar , Dongwoo Kim , Yue Yao , Zhenyue Qin , Min Xu

Spatial transcriptomics (ST) technologies can be used to align transcriptomes with histopathological morphology, presenting exciting new opportunities for biomolecular discovery. Using ST data, we construct a novel framework, GeneFlow, to…

Quantitative Methods · Quantitative Biology 2025-11-04 Mengbo Wang , Shourya Verma , Aditya Malusare , Luopin Wang , Yiyang Lu , Vaneet Aggarwal , Mario Sola , Ananth Grama , Nadia Atallah Lanman

Deep image watermarking, which refers to enabling imperceptible watermark embedding and reliable extraction in cover images, has been shown to be effective for copyright protection of image assets. However, existing methods face limitations…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Ke Liu , Xuanhan Wang , Qilong Zhang , Lianli Gao , Jingkuan Song

Visual explanation methods have an important role in the prognosis of the patients where the annotated data is limited or unavailable. There have been several attempts to use gradient-based attribution methods to localize pathology from…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Ugur Demir , Ismail Irmakci , Elif Keles , Ahmet Topcu , Ziyue Xu , Concetto Spampinato , Sachin Jambawalikar , Evrim Turkbey , Baris Turkbey , Ulas Bagci

With a large influx of dermoscopy images and a growing shortage of dermatologists, automatic dermoscopic image analysis plays an essential role in skin cancer diagnosis. In this paper, a new deep fully convolutional neural network (FCNN) is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-17 Jin Qi , Miao Le , Chunming Li , Ping Zhou

Recent advances in multimodal foundation models unifying image understanding and generation have opened exciting avenues for tackling a wide range of vision-language tasks within a single framework. Despite progress, existing unified models…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Ying Shen , Zhiyang Xu , Jiuhai Chen , Shizhe Diao , Jiaxin Zhang , Yuguang Yao , Joy Rimchala , Ismini Lourentzou , Lifu Huang

The practical deployment of medical vision-language models (Med-VLMs) necessitates seamless integration of textual data with diverse visual modalities, including 2D/3D images and videos, yet existing models typically employ separate…

Computation and Language · Computer Science 2025-04-22 Songtao Jiang , Yuan Wang , Sibo Song , Yan Zhang , Zijie Meng , Bohan Lei , Jian Wu , Jimeng Sun , Zuozhu Liu
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