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Since gyri and sulci, two basic anatomical building blocks of cortical folding patterns, were suggested to bear different functional roles, a precise mapping from brain function to gyro-sulcal patterns can provide profound insights into…

Neurons and Cognition · Quantitative Biology 2022-05-24 Li Yang , Zhibin He , Changhe Li , Junwei Han , Dajiang Zhu , Tianming Liu , Tuo Zhang

Understanding the structural and functional organization of the human brain requires a detailed examination of cortical folding patterns, among which the three-hinge gyrus (3HG) has been identified as a key structural landmark. GyralNet, a…

Neurons and Cognition · Quantitative Biology 2025-04-02 Yan Zhuang , Minheng Chen , Chao Cao , Tong Chen , Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tianming Liu , Dajiang Zhu

The human cerebral cortex is highly convoluted into convex gyri and concave sulci. It has been demonstrated that gyri and sulci are significantly different in their anatomy, connectivity, and function, besides exhibiting opposite shape…

Neurons and Cognition · Quantitative Biology 2023-02-02 Xiaowei Yu , Lu Zhang , Haixing Dai , Lin Zhao , Yanjun Lyu , Zihao Wu , Tianming Liu , Dajiang Zhu

The white-matter (micro-)structural architecture of the brain promotes synchrony among neuronal populations, giving rise to richly patterned functional connections. A fundamental problem for systems neuroscience is determining the best way…

Neurons and Cognition · Quantitative Biology 2022-11-15 Yueting Li , Qingyue Wei , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

The human cerebral cortex has many bumps and grooves called gyri and sulci. Even though there is a high inter-individual consistency for the main cortical folds, this is not the case when we examine the exact shapes and details of the…

Machine Learning · Computer Science 2024-02-01 Aymeric Gaudin , Louise Guillon , Clara Fischer , Arnaud Cachia , Denis Rivière , Jean-François Mangin , Joël Chavas

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

Machine Learning · Computer Science 2025-02-19 Parnian Jalali , Mehran Safayani

Cortical folding exhibits substantial inter-individual variability while preserving stable anatomical landmarks that enable fine-scale characterization of cortical organization. Among these, the three-hinge gyrus (3HG) serves as a key…

Neurons and Cognition · Quantitative Biology 2026-02-03 Minheng Chen , Tong Chen , Yan Zhuang , Chao Cao , Jing Zhang , Tianming Liu , Lu Zhang , Dajiang Zhu

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

Neurons and Cognition · Quantitative Biology 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Resting-state functional magnetic resonance imaging (rs-fMRI) offers a non-invasive approach to examining abnormal brain connectivity associated with brain disorders. Graph neural network (GNN) gains popularity in fMRI representation…

Quantitative Methods · Quantitative Biology 2023-08-22 Junhao Zhang , Qianqian Wang , Xiaochuan Wang , Lishan Qiao , Mingxia Liu

Catchy but rigorous deep learning architectures were tailored for image super-resolution (SR), however, these fail to generalize to non-Euclidean data such as brain connectomes. Specifically, building generative models for super-resolving a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Megi Isallari , Islem Rekik

Network representations of the nervous system have been useful for the understanding of brain phenomena such as perception, motor coordination, and memory. Although brains are composed of both neurons and glial cells, neuron-glial networks…

Neurons and Cognition · Quantitative Biology 2024-11-14 Marco Peña-Garcia , Francesco Peña-Garcia , Nelson Castro , Walter Cabrera-Febola

Brain age prediction serves as a powerful framework for assessing brain status and detecting deviations associated with neurodevelopmental and neurodegenerative disorders. However, most existing approaches emphasize whole-brain age…

Neurons and Cognition · Quantitative Biology 2026-02-10 Rongzhao He , Dalin Zhu , Ying Wang , Songhong Yue , Leilei Zhao , Yu Fu , Dan Wu , Bin Hu , Weihao Zheng

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Graph Neural Networks (GNNs) excel at learning from pairwise interactions but often overlook multi-way and hierarchical relationships. Topological Deep Learning (TDL) addresses this limitation by leveraging combinatorial topological spaces.…

Brain surface analysis is essential to neuroscience, however, the complex geometry of the brain cortex hinders computational methods for this task. The difficulty arises from a discrepancy between 3D imaging data, which is represented in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

Brain graph super-resolution (SR) is an under-explored yet highly relevant task in network neuroscience. It circumvents the need for costly and time-consuming medical imaging data collection, preparation, and processing. Current SR methods…

Machine Learning · Computer Science 2024-11-06 Pragya Singh , Islem Rekik

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Network analysis is rapidly becoming a standard tool for studying functional magnetic resonance imaging (fMRI) data. In this framework, different brain areas are mapped to the nodes of a network, whose links depict functional dependencies…

Neurons and Cognition · Quantitative Biology 2017-05-30 Rainer Kujala , Enrico Glerean , Raj Kumar Pan , Iiro P. Jääskeläinen , Mikko Sams , Jari Saramäki

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan
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