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The formation and dissociation of specific noncovalent interactions between a variety of macromolecules play a crucial role in the function of biological systems. During the last few years, three main lines of research led to a dramatic…

Biological Physics · Physics 2009-11-13 Pierre Bongrand

The effective electrostatic interaction between a pair of colloids, both of them located close to each other at an electrolyte interface, is studied by employing the full, nonlinear Poisson-Boltzmann (PB) theory within classical density…

Soft Condensed Matter · Physics 2016-08-17 Arghya Majee , Markus Bier , S. Dietrich

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

We consider an osmotic equilibrium between bulk solutions of polyelectrolyte bounded by semipermeable membranes and separated by a thin film of salt-free liquid. Although the membranes are neutral, the counter-ions of the polyelectrolyte…

Soft Condensed Matter · Physics 2012-01-19 Olga I. Vinogradova , Lyderic Bocquet , Artem N. Bogdanov , Roumen Tsekov , Vladimir Lobaskin

We present an accurate and efficient algorithm to calculate the electrostatic interaction of charged point particles with partially periodic boundary conditions that are confined along the nonperiodic direction by two metallic parallel…

Materials Science · Physics 2016-11-03 Samare Rostami , S. Alireza Ghasemi , Ehsan Nedaaee Oskoee

Modeling the electronic and optical properties of organic semiconductors remains a challenge for theory, despite the remarkable progress achieved in the last three decades. The complexity of these systems, including structural (dis)order…

Materials Science · Physics 2023-02-15 Caterina Cocchi , Michele Guerrini , Jannis Krumland , Ngoc Trung Nguyen , Ana M. Valencia

Nonlinear ionic screening theory for heterogeneously charged spheres is developed in terms of a mode-decomposition of the surface charge. A far-field analysis of the resulting electrostatic potential leads to a natural generalization of…

Soft Condensed Matter · Physics 2009-12-17 N. Boon , E. Carvajal Gallardo , S. Zheng , E. Eggen , M. Dijkstra , R. van Roij

The aim of this work is to study the electrostatic screening by single and few-layer MoS2 sheets by means of electrostatic force microscopy in combination with a non-linear Thomas-Fermi Theory to interpret the experimental results. We find…

We investigate two different types of non-Markovian coarse-grained models extracted from a linear, non-equilibrium microscopic system, featuring a tagged particle coupled to underdamped oscillators. The first model is obtained by…

Statistical Mechanics · Physics 2023-10-06 Gerhard Jung

We review some recent coarse-graining and multi-scale methods, but also put forward some new ideas for addressing such issues. We find that, if one is guided by nonequilibrium statistical mechanics and thermodynamics, it is possible to…

Soft Condensed Matter · Physics 2009-11-06 Patrick Ilg , Vlasis Mavrantzas , Hans Christian Öttinger

We estimate polarizabilities of atoms in molecules without electron density, using a Voronoi tesselation approach instead of conventional density partitioning schemes. The resulting atomic dispersion coefficients are calculated, as well as…

Chemical Physics · Physics 2015-08-31 Tristan Bereau , O. Anatole von Lilienfeld

Multiscale systems are ubiquitous in science and technology, but are notoriously challenging to simulate as short spatiotemporal scales must be appropriately linked to emergent bulk physics. When expensive high-dimensional dynamical systems…

Machine Learning · Computer Science 2025-12-30 Quercus Hernandez , Max Win , Thomas C. O'Connor , Paulo E. Arratia , Nathaniel Trask

An understanding of the hydrophobicity of complex heterogeneous molecular assemblies is crucial to characterize and predict interactions between biomolecules. As such, uncovering the subtleties of assembly processes hinges on an accurate…

Soft Condensed Matter · Physics 2015-02-20 Richard C. Remsing , John D. Weeks

In this study, we intend to solve a mutual information problem in interacting molecules of any type, such as proteins, nucleic acids, and small molecules. Using machine learning techniques, we accurately predict pairwise interactions, which…

Machine Learning · Statistics 2016-01-28 Andrew Schaumberg , Angela Yu , Tatsuhiro Koshi , Xiaochan Zong , Santoshkalyan Rayadhurgam

We formulate thermodynamically consistent coarse-graining procedures for molecular systems undergoing thermally and photo-induced transitions: starting from elementary vibronic transitions, we derive effective photo-isomerization reactions…

Statistical Mechanics · Physics 2025-10-08 Francesco Avanzini , Massimiliano Esposito , Emanuele Penocchio

The influence of a chemically or electrically heterogeneous distribution of interaction sites at a planar substrate on the number density of an adjacent fluid is studied by means of classical density functional theory (DFT). In the case of…

Soft Condensed Matter · Physics 2018-05-25 Maximilian Mußotter , Markus Bier , S. Dietrich

We propose a very simple but realistic enough model which allows to include a large number of molecules in molecular dynamics MD simulations of these bilayers, but nevertheless taking into account molecular charge distributions, flexible…

Soft Condensed Matter · Physics 2009-11-13 Z. Gamba

This article addresses reaction networks in which spatial and stochastic effects are of crucial importance. For such systems, particle-based models allow us to describe all microscopic details with high accuracy. However, they suffer from…

Polarizable particle systems, including charged colloids, polarizable ions, biomolecular assemblies, and soft nanomaterials, can exhibit contact electrostatic interactions that depart strongly from Coulomb behavior when dielectric mismatch…

Soft Condensed Matter · Physics 2026-05-13 Yanyu Duan , Zecheng Gan

The development of numerical methods capable of simulating realistic materials with strongly correlated electrons, with controllable errors, is a central challenge in quantum many-body physics. Here we describe how a hybrid between…

Strongly Correlated Electrons · Physics 2015-04-23 Alexei A. Kananenka , Emanuel Gull , Dominika Zgid