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Related papers: The embodied brain: Bridging the brain, body, and …

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Humans and animals excel in combining information from multiple sensory modalities, controlling their complex bodies, adapting to growth, failures, or using tools. These capabilities are also highly desirable in robots. They are displayed…

Robotics · Computer Science 2022-11-08 Matej Hoffmann

After Big Data and Artificial Intelligence (AI), the subject of Digital Twins has emerged as another promising technology, advocated, built, and sold by various IT companies. The approach aims to produce highly realistic models of real…

Physics and Society · Physics 2023-09-11 Dirk Helbing , Javier Argota Sánchez-Vaquerizo

Brain digital twins aim to provide faithful, individualized computational representations of brains as dynamical systems, enabling mechanistic understanding and supporting prediction of clinical interventions. Yet current approaches remain…

Computational Engineering, Finance, and Science · Computer Science 2026-04-16 Alexandre Muzy

In this paper, we will argue that if we want to understand the function of the brain (or the control in the case of robots), we must understand how the brain is embedded into the physical system, and how the organism interacts with the real…

Artificial Intelligence · Computer Science 2012-02-03 Matej Hoffmann , Rolf Pfeifer

As the real-time digital counterpart of a physical system or process, digital twins are utilized for system simulation and optimization. Neural networks are one way to build a digital twins model by using data especially when a…

Machine Learning · Computer Science 2021-12-03 Chao Sun , Victor Guang Shi

The objective of personalized medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be…

Quantitative Methods · Quantitative Biology 2024-03-22 Lucas Böttcher , Luis L. Fonseca , Reinhard C. Laubenbacher

Digital twins are transforming engineering and applied sciences by enabling real-time monitoring, simulation, and predictive analysis of physical systems and processes. However, conventional digital twins rely primarily on passive data…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Matteo Torzoni , Domenico Maisto , Andrea Manzoni , Francesco Donnarumma , Giovanni Pezzulo , Alberto Corigliano

Digital twins are virtual replicas of physical entities and are poised to transform personalized medicine through the real-time simulation and prediction of human physiology. Translating this paradigm from engineering to biomedicine…

Uncertainty is an inherent property of any complex system, especially those that integrate physical parts or operate in real environments. In this paper, we focus on the Digital Twins of adaptive systems, which are particularly complex to…

Systems and Control · Electrical Eng. & Systems 2024-02-19 Julien Deantoni , Paula Muñoz , Cláudio Gomes , Clark Verbrugge , Rakshit Mittal , Robert Heinrich , Stijn Bellis , Antonio Vallecillo

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic…

The relationship between physiological systems and modern electromechanical technologies is fast becoming intimate with high degrees of complex interaction. It can be argued that muscular function, limb movements, and touch perception serve…

Human-Computer Interaction · Computer Science 2012-03-15 Bradly Alicea

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of…

Neurons and Cognition · Quantitative Biology 2018-08-01 Nikolaus Kriegeskorte , Pamela K. Douglas

In recent years, advances in neuroscience and artificial intelligence have paved the way for unprecedented opportunities for understanding the complexity of the brain and its emulation by computational systems. Cutting-edge advancements in…

Neurons and Cognition · Quantitative Biology 2024-04-19 Hui Xiong , Congying Chu , Lingzhong Fan , Ming Song , Jiaqi Zhang , Yawei Ma , Ruonan Zheng , Junyang Zhang , Zhengyi Yang , Tianzi Jiang

Industrial process optimization and control is crucial to increase economic and ecologic efficiency. However, data sovereignty, differing goals, or the required expert knowledge for implementation impede holistic implementation. Further,…

Machine Learning · Computer Science 2024-08-28 Johannes Emmert , Ronald Mendez , Houman Mirzaalian Dastjerdi , Christopher Syben , Andreas Maier

Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

The concept of the Digital Twin, which in the context of this paper is the virtual representation of a production system or its components, can be used as a "digital playground" to master the increasing complexity of these assets. One of…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Daniel Dittler , Valentin Stegmaier , Nasser Jazdi , Michael Weyrich

We articulate the design imperatives for machine-learning based digital twins for nonlinear dynamical systems subject to external driving, which can be used to monitor the ``health'' of the target system and anticipate its future collapse.…

Adaptation and Self-Organizing Systems · Physics 2022-10-13 Ling-Wei Kong , Yang Weng , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

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