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Active metamaterials promise to enable arbitrary, temporal control over the propagation of wavefronts of light for applications such as beam steering, optical communication modulators, and holograms. This has been done in the past using…

Protein fibril accumulation at interfaces is an important step in many physiological processes and neurodegenerative diseases as well as in designing materials. Here we show, using $\beta$-lactoglobulin fibrils as a model, that semiflexible…

Biomolecules · Quantitative Biology 2015-05-20 Sophia Jordens , Emily E. Riley , Ivan Usov , Lucio Isa , Peter D. Olmsted , Raffaele Mezzenga

It is well known that today nearly one in six of the world's population has to deal with neurodegenerative disorders. While a number of medical devices have been developed for the detection, prevention, and treatments of such disorders,…

Neurons and Cognition · Quantitative Biology 2021-12-23 Swadesh Pal , Roderick Melnik

Recent electrophysiological experiments have shown that dopamine (D1) modulation of pyramidal cells in prefrontal cortex reduces spike frequency adaptation and enhances NMDA transmission. Using four models, from multicompartmental to…

Neurons and Cognition · Quantitative Biology 2017-12-12 Gabriele Scheler , Jean-Marc Fellous

Recently, the structural disorder-induced topological phase transitions in periodic systems have attracted much attention. However, in aperiodic systems such as quasicrystalline systems, the interplay between structural disorder and band…

Mesoscale and Nanoscale Physics · Physics 2024-08-08 Tan Peng , Yong-Chen Xiong , Chun-Bo Hua , Zheng-Rong Liu , Xiaolu Zhu , Wei Cao , Fang Lv , Yue Hou , Bin Zhou , Ziyu Wang , Rui Xiong

We consider the patterns of collective motion emerging when many aligning, self-propelling units move in two dimensions while interacting through a repulsive potential and are also subject to delays and random perturbations. In this…

Soft Condensed Matter · Physics 2023-11-14 Fatemeh Pakpour , Tamás Vicsek

This article reviews the unconventional effects of random disorder on magnetic quantum phase transitions, focusing on a number of new experimental and theoretical developments during the last three years. On the theory side, we address…

Strongly Correlated Electrons · Physics 2014-08-26 Thomas Vojta

Chaperonins are biological nanomachines that help newly translated proteins to fold by rescuing them from kinetically trapped misfolded states. Protein folding assistance by the chaperonin machinery is obligatory in vivo for a subset of…

Biomolecules · Quantitative Biology 2022-11-29 George Stan , George H. Lorimer , D. Thirumalai

The presence of oligomeric aggregates, which is often observed during the process of amyloid formation, has recently attracted much attention since it has been associated with neurodegenerative conditions such as Alzheimer's and Parkinson's…

Biomolecules · Quantitative Biology 2009-01-14 Stefan Auer , Filip Meersman , Christopher M. Dobson , Michele Vendruscolo

We consider a particle in one dimension submitted to amplitude and phase disorder. It can be mapped onto the complex Burgers equation, and provides a toy model for problems with interplay of interferences and disorder, such as the NSS model…

Disordered Systems and Neural Networks · Physics 2015-03-17 Alexander Dobrinevski , Pierre Le Doussal , Kay Jörg Wiese

Inspired by recent experiments on the dynamics of particles and polymers in artificial cytoskeletons and in cells, we introduce a modified Langevin equation for a particle in an environment that is a viscoelastic medium and that is brought…

Soft Condensed Matter · Physics 2016-11-08 Hans Vandebroek , Carlo Vanderzande

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

Cell Behavior · Quantitative Biology 2016-06-29 Davide Ambrosi , Anna Zanzottera

Transforming growth factor beta (TGF$\beta$) plays a central role in morphogenesis, growth, and cell differentiation. This cytokine is particularly important in cartilage where it regulates cell proliferation and extracellular matrix…

Tissues and Organs · Quantitative Biology 2015-05-27 Catherine Baugé , Olivier Cauvard , Sylvain Leclercq , Philippe Galéra , Karim Boumédiene

We consider a three dimensional, generalized version of the original SPP model for collective motion. By extending the factors influencing the ordering, we investigate the case when the movement of the self-propelled particles (SPP-s)…

Statistical Mechanics · Physics 2009-02-11 Peter Szabo , Mate Nagy , Tamas Vicsek

The microscopic description of spin-Peierls substances is discussed. Particular attention is paid to the ordered (dimerised and incommensurably modulated) phases. Important points are the adiabatic and the antiadiabatic approach, generic…

Strongly Correlated Electrons · Physics 2009-10-31 Götz S. Uhrig

Biological forces govern essential cellular and molecular processes in all living organisms. Many cellular forces, e.g. those generated in cyclic conformational changes of biological machines, have repetitive components. However, little is…

Biomolecules · Quantitative Biology 2008-09-17 P. Szymczak , Harald Janovjak

Biomembranes wrapping cells and organelles are not only the partitions that separate the insides but also dynamic fields for biological functions accompanied by membrane shape changes. In this review, we discuss the spatiotemporal patterns…

Soft Condensed Matter · Physics 2025-01-22 Hiroshi Noguchi

Most of our quantitative understanding of disorder-induced metal-insulator transitions comes from numerical studies of simple noninteracting tight-binding models, like the Anderson model in three dimensions. An important outstanding problem…

Quantum Gases · Physics 2020-10-07 Filippo Stellin , Giuliano Orso

The phase behaviour of a single large semiflexible polymer immersed in a suspension of spherical particles is studied. All interactions are simple excluded volume interactions and the diameter of the spherical particles is an order of…

Soft Condensed Matter · Physics 2009-10-30 Richard P. Sear

The recently developed refractory multi-principle element alloy (MPEA), AlMo$_{0.5}$NbTa$_{0.5}$TiZr, shows an interesting microstructure with cuboidal precipitates of a disordered phase (${\beta}$, bcc) coherently embedded in an ordered…

Materials Science · Physics 2021-11-04 Kamalnath Kadirvel , Zachary Kloenne , Jacob K Jensen , Hamish Fraser , Yunzhi Wang