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High-fidelity electron microscopy simulations required for quantitative crystal structure refinements face a fundamental challenge: while physical interactions are well-described theoretically, real-world experimental effects are…

In this paper, we present a method of embedding physics data manifolds with metric structure into lower dimensional spaces with simpler metrics, such as Euclidean and Hyperbolic spaces. We then demonstrate that it can be a powerful step in…

High Energy Physics - Phenomenology · Physics 2023-08-02 Sang Eon Park , Philip Harris , Bryan Ostdiek

Physics-driven discovery in an autonomous experiment has emerged as a dream application of machine learning in physical sciences. Here we develop and experimentally implement a deep kernel learning workflow combining the correlative…

Materials Science · Physics 2022-11-24 Kevin M. Roccapriore , Sergei V. Kalinin , Maxim Ziatdinov

Metasurfaces, typically realized as arrays of nanopillars, transform electromagnetic (EM) fields depending on their geometry and spatial arrangement. For solving the inverse problem of designing new metasurfaces that transform EM fields in…

The 3D characterization of microstructures is crucial for understanding and designing functional materials. However, the scanning electron microscope (SEM), widely used in scientific research, captures only 2D electron intensity…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shuo Chen , Yijin Li , Xi Zheng , Guofeng Zhang

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Ruiqing Sun , Delong Yang , Shaohui Zhang , Qun Hao

In this paper, we develop a deep learning approach for the accurate solution of challenging problems of near-field microscopy that leverages the powerful framework of physics-informed neural networks (PINNs) for the inversion of the complex…

Optics · Physics 2024-06-12 Yuyao Chen , Luca Dal Negro

We present an elastic simulator for domains defined as evolving implicit functions, which is efficient, robust, and differentiable with respect to both shape and material. This simulator is motivated by applications in 3D reconstruction: it…

Graphics · Computer Science 2025-04-09 Gilles Daviet , Tianchang Shen , Nicholas Sharp , David I. W. Levin

Ptychography spans from sub-angstrom to meter scales yet suffers from convergence instability and excessive data redundancy. Here we introduce self-correcting residual neural fields as a dose-efficient framework for electron, X-ray, and…

If we are ever to unravel the mysteries of brain function at its most fundamental level, we will need a precise understanding of how its component neurons connect to each other. Electron Microscopes (EM) can now provide the nanometer…

Computer Vision and Pattern Recognition · Computer Science 2016-09-28 Pascal Fua , Graham Knott

A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing…

Computer Vision and Pattern Recognition · Computer Science 2012-10-03 Tao Hu , Juan Nunez-Iglesias , Shiv Vitaladevuni , Lou Scheffer , Shan Xu , Mehdi Bolorizadeh , Harald Hess , Richard Fetter , Dmitri Chklovskii

Deep learning affords enormous opportunities to augment the armamentarium of biomedical imaging, albeit its design and implementation have potential flaws. Fundamentally, most deep learning models are driven entirely by data without…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Liyue Shen , Wei Zhao , Dante Capaldi , John Pauly , Lei Xing

Direct observation of nanoscale transformations in three dimensions (3D) is essential for understanding materials evolution under operating conditions, yet dynamic electron tomography remains limited by slow tilt series acquisition and by…

Reconstructing and simulating dynamic 3D scenes with both visual realism and physical consistency remains a fundamental challenge. Existing neural representations, such as NeRFs and 3DGS, excel in appearance reconstruction but struggle to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Dan Wang , Xinrui Cui , Serge Belongie , Ravi Ramamoorthi

We present a deep learning driven computational approach to overcome the limitations of self-interference digital holography that imposed by inferior axial imaging performances. We demonstrate a 3D deep neural network model can…

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Structured light has proven instrumental in 3D imaging, LiDAR, and holographic light projection. Metasurfaces, comprised of sub-wavelength-sized nanostructures, facilitate 180$^\circ$ field-of-view (FoV) structured light, circumventing the…

Reconstructing soft tissues from stereo endoscope videos is an essential prerequisite for many medical applications. Previous methods struggle to produce high-quality geometry and appearance due to their inadequate representations of 3D…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruyi Zha , Xuelian Cheng , Hongdong Li , Mehrtash Harandi , Zongyuan Ge

Comprehensive, synapse-resolution imaging of the brain will be crucial for understanding neuronal computations and function. In connectomics, this has been the sole purview of volume electron microscopy (EM), which entails an excruciatingly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Yicong Li , Yaron Meirovitch , Aaron T. Kuan , Jasper S. Phelps , Alexandra Pacureanu , Wei-Chung Allen Lee , Nir Shavit , Lu Mi

Decoding visual information from electroencephalography (EEG) has recently achieved promising results, primarily focusing on reconstructing two-dimensional (2D) images from brain activity. However, the reconstruction of three-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Emanuele Balloni , Emanuele Frontoni , Chiara Matti , Marina Paolanti , Roberto Pierdicca , Emiliano Santarnecchi
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